A Physiologically Based Pharmacokinetic Model of Mitoxantrone in Mice and Scale-up to Humans: a Semi-Mechanistic Model Incorporating DNA and Protein Binding

Title
A Physiologically Based Pharmacokinetic Model of Mitoxantrone in Mice and Scale-up to Humans: a Semi-Mechanistic Model Incorporating DNA and Protein Binding
Authors
Keywords
-
Journal
AAPS Journal
Volume 14, Issue 2, Pages 352-364
Publisher
American Association of Pharmaceutical Scientists (AAPS)
Online
2012-03-27
DOI
10.1208/s12248-012-9344-7

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