Bioapplications of Cell-SELEX-Generated Aptamers in Cancer Diagnostics, Therapeutics, Theranostics and Biomarker Discovery: A Comprehensive Review

Circular Bivalent Aptamers Enable in Vivo Stability and Recognition

(2017) Hailan Kuai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular Elucidation of Disease Biomarkers at the Interface of Chemistry and Biology

(2017) Liqin Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aptamers against Cells Overexpressing Glypican 3 from Expanded Genetic Systems Combined with Cell Engineering and Laboratory Evolution

(2016) Liqin Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Heterocyclic Carbene-Gold(I) Complexes Conjugated to a Leukemia-Specific DNA Aptamer for Targeted Drug Delivery

(2016) Weijia Niu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

3D Cell-SELEX: Development of RNA aptamers as molecular probes for PC-3 tumor cell line

(2016) Aline G. Souza et al.   EXPERIMENTAL CELL RESEARCH

Using modified aptamers for site specific protein–aptamer conjugations

(2016) Ruowen Wang et al.   Chemical Science

Using DNA Aptamer Probe for Immunostaining of Cancer Frozen Tissues

(2015) Ying Pu et al.   ANALYTICAL CHEMISTRY

Ortho-Stabilized18F-Azido Click Agents and their Application in PET Imaging with Single-Stranded DNA Aptamers

(2015) Lu Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Versatile Approach Towards Nucleobase-Modified Aptamers

(2015) Fabian Tolle et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Evolution of Functional Six-Nucleotide DNA

(2015) Liqin Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Live-Cell Labeling of Specific Protein Glycoforms by Proximity-Enhanced Bioorthogonal Ligation

(2015) Peter V. Robinson et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Self-assembly of DNA Nanohydrogels with Controllable Size and Stimuli-Responsive Property for Targeted Gene Regulation Therapy

(2015) Juan Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Facile Discovery of Cell-Surface Protein Targets of Cancer Cell Aptamers

(2015) Tao Bing et al.   MOLECULAR & CELLULAR PROTEOMICS

Using aptamers to elucidate esophageal cancer clinical samples

(2015) Zhenxu Liu et al.   Scientific Reports

DNA Nanoflowers for Multiplexed Cellular Imaging and Traceable Targeted Drug Delivery

(2014) Rong Hu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Selection of RNA aptamers against the M. tuberculosis EsxG protein using surface plasmon resonance-based SELEX

(2014) Nqobile A.C. Ngubane et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A strain-promoted alkyne–azide cycloaddition (SPAAC) reaction of a novel EpCAM aptamer–fluorescent conjugate for imaging of cancer cells

(2014) Nithya Subramanian et al.   CHEMICAL COMMUNICATIONS

Activatable Fluorescence/MRI Bimodal Platform for Tumor Cell Imaging via MnO2 Nanosheet–Aptamer Nanoprobe

(2014) Zilong Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Automated Modular Synthesis of Aptamer–Drug Conjugates for Targeted Drug Delivery

(2014) RuoWen Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Detection and Characterization of Cancer Cells and Pathogenic Bacteria Using Aptamer-Based Nano-Conjugates

(2014) Vinayakumar Gedi et al.   SENSORS

A Spherical Nucleic Acid Platform Based on Self-Assembled DNA Biopolymer for High-Performance Cancer Therapy

(2013) Jing Zheng et al.   ACS Nano

Gold-Coated Fe3O4Nanoroses with Five Unique Functions for Cancer Cell Targeting, Imaging, and Therapy

(2013) Chunmei Li et al.   ADVANCED FUNCTIONAL MATERIALS

Selection of DNA Aptamers against Epithelial Cell Adhesion Molecule for Cancer Cell Imaging and Circulating Tumor Cell Capture

(2013) Yanling Song et al.   ANALYTICAL CHEMISTRY

DNA Micelle Flares for Intracellular mRNA Imaging and Gene Therapy

(2013) Tao Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Noncanonical Self-Assembly of Multifunctional DNA Nanoflowers for Biomedical Applications

(2013) Guizhi Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Building a Multifunctional Aptamer-Based DNA Nanoassembly for Targeted Cancer Therapy

(2013) Cuichen Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA “Nano-Claw”: Logic-Based Autonomous Cancer Targeting and Therapy

(2013) Mingxu You et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Generation of high-affinity DNA aptamers using an expanded genetic alphabet

(2013) Michiko Kimoto et al.   NATURE BIOTECHNOLOGY

Whole Cell-SELEX Aptamers for Highly Specific Fluorescence Molecular Imaging of Carcinomas In Vivo

(2013) Hui Shi et al.   PLoS One

Self-assembled, aptamer-tethered DNA nanotrains for targeted transport of molecular drugs in cancer theranostics

(2013) G. Zhu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vitro selection with artificial expanded genetic information systems

(2013) K. Sefah et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aptamer to ErbB-2/HER2 enhances degradation of the target and inhibits tumorigenic growth

(2013) G. Mahlknecht et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vivo SELEX for Identification of Brain-penetrating Aptamers

(2013) Congsheng Cheng et al.   Molecular Therapy-Nucleic Acids

Consecutive Targetable Smart Nanoprobe for Molecular Recognition of Cytoplasmic microRNA in Metastatic Breast Cancer

(2012) Eunjung Kim et al.   ACS Nano

Assembly of Aptamer Switch Probes and Photosensitizer on Gold Nanorods for Targeted Photothermal and Photodynamic Cancer Therapy

(2012) Jian Wang et al.   ACS Nano

DNA Aptamer-Mediated Cell Targeting

(2012) Xiangling Xiong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aptamer-Based Affinity Labeling of Proteins

(2012) Jan L. Vinkenborg et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cancer biomarkers

(2012) N. Lynn Henry et al.   Molecular Oncology

A Logic-Gated Nanorobot for Targeted Transport of Molecular Payloads

(2012) S. M. Douglas et al.   SCIENCE

Biomarkers: hopes and challenges in the path from discovery to clinical practice

(2012) Nikolaos G. Frangogiannis   Translational Research

Dressed for success – applying chemistry to modulate aptamer functionality

(2012) Fabian Tolle et al.   Chemical Science

Smart Multifunctional Nanostructure for Targeted Cancer Chemotherapy and Magnetic Resonance Imaging

(2011) Tao Chen et al.   ACS Nano

Self-Assembly of a Bifunctional DNA Carrier for Drug Delivery

(2011) Kelong Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A tumor mRNA-dependent gold nanoparticle–molecular beacon carrier for controlled drug release and intracellular imaging

(2011) Guangming Qiao et al.   CHEMICAL COMMUNICATIONS

Aptamer-Based Switchable Nanovalves for Stimuli-Responsive Drug Delivery

(2011) Veli C. Özalp et al.   CHEMISTRY-A EUROPEAN JOURNAL

Activatable aptamer probe for contrast-enhanced in vivo cancer imaging based on cell membrane protein-triggered conformation alteration

(2011) H. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nucleic Acid-Gold Nanoparticle Conjugates as Mimics of microRNA

(2011) Liangliang Hao et al.   Small

Molecular diagnostic and drug delivery agents based on aptamer-nanomaterial conjugates

(2010) Jung Heon Lee et al.   ADVANCED DRUG DELIVERY REVIEWS

Review: Aptamers in microfluidic chips

(2010) Yuanhong Xu et al.   ANALYTICA CHIMICA ACTA

Isolation of RNA Aptamers Targeting HER-2-overexpressing Breast Cancer Cells Using Cell-SELEX

(2010)   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Automation in the High-throughput Selection of Random Combinatorial Libraries—Different Approaches for Select Applications

(2010) Jörn Glökler et al.   MOLECULES

Development of DNA aptamers using Cell-SELEX

(2010) Kwame Sefah et al.   Nature Protocols

What are biomarkers?

(2010) Kyle Strimbu et al.   Current Opinion in HIV and AIDS

Aptamers Generated from Cell-SELEX for Molecular Medicine: A Chemical Biology Approach

(2009) Xiaohong Fang et al.   ACCOUNTS OF CHEMICAL RESEARCH

Molecular Assembly of an Aptamer-Drug Conjugate for Targeted Drug Delivery to Tumor Cells

(2009) Yu-Fen Huang et al.   CHEMBIOCHEM

A Nucleolin-Targeted Multimodal Nanoparticle Imaging Probe for Tracking Cancer Cells Using an Aptamer

(2009) D. W. Hwang et al.   JOURNAL OF NUCLEAR MEDICINE

Identification of an aptamer targeting hnRNP A1 by tissue slide‐based SELEX

(2009) Shaohua Li et al.   JOURNAL OF PATHOLOGY

Technical and Biological Issues Relevant to Cell Typing with Aptamers

(2009) Na Li et al.   JOURNAL OF PROTEOME RESEARCH

Gene Regulation with Polyvalent siRNA−Nanoparticle Conjugates

(2009) David A. Giljohann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular recognition of acute myeloid leukemia using aptamers

(2009) K Sefah et al.   LEUKEMIA

Complex Target SELEX

(2008) Steven M. Shamah et al.   ACCOUNTS OF CHEMICAL RESEARCH

Identification of Liver Cancer-Specific Aptamers Using Whole Live Cells

(2008) Dihua Shangguan et al.   ANALYTICAL CHEMISTRY

Superparamagnetic Iron Oxide Nanoparticle-Aptamer Bioconjugates for Combined Prostate Cancer Imaging and Therapy

(2008) Andrew Z. Wang et al.   ChemMedChem

Molecular Recognition of Small-Cell Lung Cancer Cells Using Aptamers

(2008) Hui William Chen et al.   ChemMedChem

Cell-Specific Aptamer Probes for Membrane Protein Elucidation in Cancer Cells

(2008) Dihua Shangguan et al.   JOURNAL OF PROTEOME RESEARCH

Regulation of Singlet Oxygen Generation Using Single-Walled Carbon Nanotubes

(2008) Zhi Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aptamer-Facilitated Biomarker Discovery (AptaBiD)

(2008) Maxim V. Berezovski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Selective Photothermal Therapy for Mixed Cancer Cells Using Aptamer-Conjugated Nanorods

(2008) Yu-Fen Huang et al.   LANGMUIR

Molecular assembly for high-performance bivalent nucleic acid inhibitor

(2008) Y. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Precise engineering of targeted nanoparticles by using self-assembled biointegrated block copolymers

(2008) F. Gu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Improvement of Aptamer Affinity by Dimerization

(2008) Hijiri Hasegawa et al.   SENSORS

Cell Specific Aptamer–Photosensitizer Conjugates as a Molecular Tool in Photodynamic Therapy

(2007) Prabodhika Mallikaratchy et al.   ChemMedChem