Evidence of link between quorum sensing and sugar metabolism inEscherichia colirevealed via cocrystal structures of LsrK and HPr

Engineered probiotic Escherichia coli can eliminate and prevent Pseudomonas aeruginosa gut infection in animal models

(2017) In Young Hwang et al.   Nature Communications

Mathematical model of LsrR-binding and derepression in Escherichia coli K12

(2017) Steven M. Graff et al.   Journal of Bioinformatics and Computational Biology

Increasing the soluble expression and crystallization of theEscherichia coliquorum-sensing protein LsrK

(2017) Jung-Hye Ha et al.   Acta Crystallographica Section F-Structural Biology Communications

Synchronized cycles of bacterial lysis for in vivo delivery

(2016) M. Omar Din et al.   NATURE

Dali server update

(2016) Liisa Holm et al.   NUCLEIC ACIDS RESEARCH

Mechanisms of bacterial persistence during stress and antibiotic exposure

(2016) Alexander Harms et al.   SCIENCE

Chemotaxis towards autoinducer 2 mediates autoaggregation in Escherichia coli

(2016) Leanid Laganenka et al.   Nature Communications

Synthetic biology expands chemical control of microorganisms

(2015) Tyler J Ford et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Living in the matrix: assembly and control of Vibrio cholerae biofilms

(2015) Jennifer K. Teschler et al.   NATURE REVIEWS MICROBIOLOGY

The Bacterial Phosphoenolpyruvate:Carbohydrate Phosphotransferase System: Regulation by Protein Phosphorylation and Phosphorylation-Dependent Protein-Protein Interactions

(2014) Josef Deutscher et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Deciphering key features in protein structures with the new ENDscript server

(2014) Xavier Robert et al.   NUCLEIC ACIDS RESEARCH

Advancements in the Development of HIF-1α-Activated Protein Switches for Use in Enzyme Prodrug Therapy

(2014) R. Clay Wright et al.   PLoS One

Mechanistic Insights into the LsrK Kinase Required for Autoinducer-2 Quorum Sensing Activation

(2013) Jie Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Crystal Structures of the LsrR Proteins Complexed with Phospho-AI-2 and Two Signal-Interrupting Analogues Reveal Distinct Mechanisms for Ligand Recognition

(2013) Jung-Hye Ha et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

HPr antagonizes the anti- 70 activity of Rsd in Escherichia coli

(2013) Y.-H. Park et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Towards automated crystallographic structure refinement withphenix.refine

(2012) Pavel V. Afonine et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structure and Function of Human Xylulokinase, an Enzyme with Important Roles in Carbohydrate Metabolism

(2012) Richard D. Bunker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphoenolpyruvate phosphotransferase system regulates detection and processing of the quorum sensing signal autoinducer-2

(2012) Catarina S. Pereira et al.   MOLECULAR MICROBIOLOGY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Engineering microbes to sense and eradicate Pseudomonas aeruginosa, a human pathogen

(2011) N. Saeidi et al.   Molecular Systems Biology

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Solution Structure of the 128 kDa Enzyme I Dimer fromEscherichia coliand Its 146 kDa Complex with HPr Using Residual Dipolar Couplings and Small- and Wide-Angle X-ray Scattering

(2010) Charles D. Schwieters et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthetic Analogs Tailor Native AI-2 Signaling Across Bacterial Species

(2010) Varnika Roy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Autonomous induction of recombinant proteins by minimally rewiring native quorum sensing regulon of E. coli

(2010) Chen-Yu Tsao et al.   METABOLIC ENGINEERING

Synthetic biology: applications come of age

(2010) Ahmad S. Khalil et al.   NATURE REVIEWS GENETICS

LsrR-binding site recognition and regulatory characteristics in Escherichia coli AI-2 quorum sensing

(2009) Ting Xue et al.   CELL RESEARCH

Screen for Leukotoxin Mutants in Aggregatibacter actinomycetemcomitans: Genes of the Phosphotransferase System Are Required for Leukotoxin Biosynthesis

(2008) M. P. Isaza et al.   INFECTION AND IMMUNITY