Human Clade 2.3.4.4 A/H5N6 Influenza Virus Lacks Mammalian Adaptation Markers and Does Not Transmit via the Airborne Route between Ferrets

Tropism and innate host responses of influenza A/H5N6 virus: an analysis ofex vivoandin vitrocultures of the human respiratory tract

(2017) Kenrie P. Y. Hui et al.   EUROPEAN RESPIRATORY JOURNAL

Genetic characterisation of novel, highly pathogenic avian influenza (HPAI) H5N6 viruses isolated in birds, South Korea, November 2016

(2017) Young-Jae Si et al.   Eurosurveillance

Genesis, Evolution and Prevalence of H5N6 Avian Influenza Viruses in China

(2016) Yuhai Bi et al.   Cell Host & Microbe

Human infection with a novel, highly pathogenic avian influenza A (H5N6) virus: Virological and clinical findings

(2016) Ming Pan et al.   JOURNAL OF INFECTION

Multiple Natural Substitutions in Avian Influenza A Virus PB2 Facilitate Efficient Replication in Human Cells

(2016) Benjamin Mänz et al.   JOURNAL OF VIROLOGY

Amino Acid Substitutions That Affect Receptor Binding and Stability of the Hemagglutinin of Influenza A/H7N9 Virus

(2016) Eefje J. A. Schrauwen et al.   JOURNAL OF VIROLOGY

Highly Pathogenic Avian Influenza H5N6 Viruses Exhibit Enhanced Affinity for Human Type Sialic Acid Receptor and In-Contact Transmission in Model Ferrets

(2016) Honglei Sun et al.   JOURNAL OF VIROLOGY

Molecular Characterizations of Surface Proteins Hemagglutinin and Neuraminidase from Recent H5Nx Avian Influenza Viruses

(2016) Hua Yang et al.   JOURNAL OF VIROLOGY

Genesis and Dissemination of Highly Pathogenic H5N6 Avian Influenza Viruses

(2016) Lei Yang et al.   JOURNAL OF VIROLOGY

Molecular requirements for a pandemic influenza virus: An acid-stable hemagglutinin protein

(2016) Marion Russier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role for migratory wild birds in the global spread of avian influenza H5N8

(2016)   SCIENCE

Continuing Reassortant of H5N6 Subtype Highly Pathogenic Avian Influenza Virus in Guangdong

(2016) Runyu Yuan et al.   Frontiers in Microbiology

Pathogenesis and Transmission of Novel Highly Pathogenic Avian Influenza H5N2 and H5N8 Viruses in Ferrets and Mice

(2015) Joanna A. Pulit-Penaloza et al.   JOURNAL OF VIROLOGY

Human Infection with a Novel Avian Influenza A(H5N6) Virus

(2015) Zi-Feng Yang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Development of high-yield influenza A virus vaccine viruses

(2015) Jihui Ping et al.   Nature Communications

Low Virulence and Lack of Airborne Transmission of the Dutch Highly Pathogenic Avian Influenza Virus H5N8 in Ferrets

(2015) Mathilde Richard et al.   PLoS One

Identification, Characterization, and Natural Selection of Mutations Driving Airborne Transmission of A/H5N1 Virus

(2014) Martin Linster et al.   CELL

Amino Acid Substitutions in Polymerase Basic Protein 2 Gene Contribute to the Pathogenicity of the Novel A/H7N9 Influenza Virus in Mammalian Hosts

(2014) C. K. P. Mok et al.   JOURNAL OF VIROLOGY

Pathobiological features of a novel, highly pathogenic avian influenza A(H5N8) virus

(2014) Young-Il Kim et al.   Emerging Microbes & Infections

The pH of Activation of the Hemagglutinin Protein Regulates H5N1 Influenza Virus Replication and Pathogenesis in Mice

(2013) H. Zaraket et al.   JOURNAL OF VIROLOGY

Increased Acid Stability of the Hemagglutinin Protein Enhances H5N1 Influenza Virus Growth in the Upper Respiratory Tract but Is Insufficient for Transmission in Ferrets

(2013) H. Zaraket et al.   JOURNAL OF VIROLOGY

Adaptive mutations in the H5N1 polymerase complex

(2013) Gülsah Gabriel et al.   VIRUS RESEARCH

Influenza HA Subtypes Demonstrate Divergent Phenotypes for Cleavage Activation and pH of Fusion: Implications for Host Range and Adaptation

(2013) Summer E. Galloway et al.   PLoS Pathogens

The Multibasic Cleavage Site in H5N1 Virus Is Critical for Systemic Spread along the Olfactory and Hematogenous Routes in Ferrets

(2012) E. J. A. Schrauwen et al.   JOURNAL OF VIROLOGY

Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets

(2012) Masaki Imai et al.   NATURE

Comparison of Temporal and Spatial Dynamics of Seasonal H3N2, Pandemic H1N1 and Highly Pathogenic Avian Influenza H5N1 Virus Infections in Ferrets

(2012) Judith M. A. van den Brand et al.   PLoS One

Modification of the Ferret Model for Pneumonia From Seasonal Human Influenza A Virus Infection

(2012) J. M. A. van den Brand et al.   VETERINARY PATHOLOGY

Pathogenesis of Influenza A/H5N1 Virus Infection in Ferrets Differs between Intranasal and Intratracheal Routes of Inoculation

(2011) Rogier Bodewes et al.   AMERICAN JOURNAL OF PATHOLOGY

Acquisition of Human-Type Receptor Binding Specificity by New H5N1 Influenza Virus Sublineages during Their Emergence in Birds in Egypt

(2011) Yohei Watanabe et al.   PLoS Pathogens

Transmission of Influenza Virus in a Mammalian Host Is Increased by PB2 Amino Acids 627K or 627E/701N

(2009) John Steel et al.   PLoS Pathogens

Analysis of a point mutation in H5N1 avian influenza virus hemagglutinin in relation to virus entry into live mammalian cells

(2008) Yan Su et al.   ARCHIVES OF VIROLOGY

Interaction of Polymerase Subunit PB2 and NP with Importin α1 Is a Determinant of Host Range of Influenza A Virus

(2008) Gülsah Gabriel et al.   PLoS Pathogens