Article
Environmental Sciences
Ji Zhao, De-yun Bu, Na Zhang, Da-nian Tian, Li-ya Ma, Hui-fang Yang
Summary: The study showed that functionalized mesoporous silica has cytotoxicity to human umbilical vein endothelial cells, but the toxicity is lower compared to unmodified mesoporous silica. Oxidative damage and cell membrane damage may be two mechanisms of cytotoxicity. Mesoporous silica has an effect on the cardiovascular system by inducing high expression of certain factors in HUVECs.
ENVIRONMENTAL TOXICOLOGY
(2021)
Article
Chemistry, Physical
Chunyu Zhang, Guozhu Liu, Quanfu Long, Chan Wu, Li Wang
Summary: This study demonstrates the promising performance of oxygen-doped porous carbon materials for the electrochemical two-electron oxygen reduction reaction (2e(-) ORR). The authors prepared oxygen-functionalized porous carbon materials using different methods and investigated their activity and selectivity in the reaction. The catalyst modified with hydrogen peroxide solution hydrothermal treatment showed the highest catalytic activity and selectivity, as well as good stability.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Pharmacology & Pharmacy
Islam M. Adel, Mohamed F. ElMeligy, Mohammed S. Amer, Nermeen A. Elkasabgy
Summary: This research aimed to evaluate the efficacy of sustained delivery of rosuvastatin for healing bone tissue damage using silica nanoparticles entrapped in alginate hydrogel. The results showed that the formulated nanoparticles had high drug content and sustained release up to 4 weeks. The fabricated hydrogel further delayed drug release and promoted new bone tissue formation in vivo.
INTERNATIONAL JOURNAL OF PHARMACEUTICS-X
(2023)
Article
Biotechnology & Applied Microbiology
Sayed Behnam Abdulahy, Mona Esmaeili Bidhendi, Mohammad Reza Vaezi, Mehrdad Moosazadeh Moghaddam
Summary: Zoledronic acid (ZA) is a drug that stimulates the growth and differentiation of osteoblast cells, promoting bone formation and preventing bone loss. Halloysite Nanotubes (HNTs) have attracted attention for their drug carrying and controlled release capabilities. This study developed a Gelatin-based scaffold with HNTs that effectively released ZA, enhanced mechanical properties, and promoted osteogenic differentiation.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Engineering, Multidisciplinary
Yajun Chen, Hanglan Qin, Alfred Mensaha, Qingqing Wang, Fenglin Huang, Qufu Wei
Summary: Designing multifunctional medical adhesives with strong adhesiveness under water is challenging, but a combination of hydrogel matrix and nanocrystal fillers has shown potential. This hydrogel adhesive mechanism relies on absorption of interfacial water and hydration process of nanocrystals for strong cohesion, with further improvement through noncovalent and covalent bonds.
COMPOSITES PART B-ENGINEERING
(2021)
Article
Biochemistry & Molecular Biology
Julia C. C. Steinbach, Fabio Fait, Hermann A. A. Mayer, Andreas Kandelbauer
Summary: This study focuses on the synthesis and properties of hybrid organic/inorganic nanocomposites. A quantitative model with high robustness and predictive power was established, demonstrating the complex nonlinear behaviors and partly synergistic interactions between process factors in determining the material properties.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Materials Science, Multidisciplinary
Raluca-Stefania Danila, Roxana-Maria Amarandi, Maria Ignat, Aurel Pui
Summary: In this study, α-glucosidase was successfully coupled to an amino-functionalized magnesium ferrite and hydroxyapatite mesoporous nanocomposite (MgFe2O4@HaP@APTES). Results showed that both enzyme activity and magnetic properties were preserved after coupling, suggesting the suitability of this nanocomposite system for inclusion into bioanalytical platforms for enzyme inhibitor screening.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Chemistry, Physical
Chaokun Yang, Yanglin Chen, Xin Wang, Jianmin Sun
Summary: This study proposes a catalyst made by combining polymeric ionic liquid (PIL) with mesoporous silica (mSiO(2)) to promote the cycloaddition reaction between carbon dioxide (CO2) and epoxides. The catalyst exhibits excellent catalytic activity and recyclability, making it a promising solution for the effective fixation and utilization of CO2.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Nanoscience & Nanotechnology
Bing Li, Miryam Criado-Gonzalez, Alexandre Adam, Joelle Bizeau, Christophe Melart, Alain Carvalho, Sylvie Begin, Dominique Begin, Loic Jierry, Damien Mertz
Summary: This article introduces the development of nanocomposite supramolecular hydrogels and discusses their potential applications in antitumor and tissue engineering. Through the enzyme-assisted self-assembly method, smart thermoresponsive nanocomposite supramolecular hydrogels can be designed.
ACS APPLIED NANO MATERIALS
(2022)
Article
Engineering, Chemical
John-Timothy Anyanwu, Yiren Wang, Ralph T. Yang
Summary: The water concentration significantly influences amine loading and grafting rate on SBA-15 mesoporous silica, with water being more effective than alcohol. Beyond a certain threshold, increasing aminosilane content does not result in higher amine loading. The mere presence of water during grafting accelerates the complete grafting of amines to supports in a short period of time.
CHEMICAL ENGINEERING SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Su-Hwan Kim, Kwangsoo Shin, Byung-Gee Kim, Nathaniel S. S. Hwang, Taeghwan Hyeon
Summary: The combination of mesoporous silica nanoparticles (MSNs) and tyrosinase enables immediate adhesion and long-term sustainability of biological tissues, making it a promising strategy for tissue adhesives in clinical settings.
CHEMICAL COMMUNICATIONS
(2022)
Article
Polymer Science
Xiao Chen, Mengfan Zhang, Di Zhu, Jing Zhang, Kai Shi, Hongjun Yang, Shaojin Gu, Pu Xiao, Yingshan Zhou
Summary: Carboxylated PVA nanocomposite hydrogels were fabricated by synthesizing carboxylated PVA with acrylate groups and UV-irradiating the mixture of PVAGMACOOH solution and nano-scale hydroxyapatite (HAP). The hydrogel exhibited excellent compressive and tensile strength, as well as enhanced cytocompatibility and cell adhesion, making it a potential candidate for biomedical applications.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Alexandra Semenova, Luke W. Giles, Mark Louis P. Vidallon, Bart Follink, Paul L. Brown, Rico F. Tabor
Summary: The increasing demand for copper resources and the accompanying pollution have created an urgent need for effective materials for copper binding and extraction. This study investigates the interaction between copper ions and PEI-silica nanocomposite particles and precursor PEI microgels. The results show that PEI-silica composites have enhanced copper binding capacity compared to the parent microgels, and the presence of silica nanoparticles increases the number of copper-binding sites in the PEI network. The PEI-silica composites can be easily recycled by washing in nitric acid, allowing for multiple cycles of efficient copper removal and extraction.
Article
Chemistry, Multidisciplinary
Lanying Guo, Jiantao Ping, Jinglei Qin, Mu Yang, Xi Wu, Mei You, Fangtian You, Hongshang Peng
Summary: The study found that oily drugs can be efficiently loaded into both types of HMSNs, while HMSNs are not good carriers for hydrophobic drugs especially planar drugs. HMSNs have high loading efficiency for oppositely charged hydrophilic drugs, which alters the zeta potential of drug-loaded HMSNs.
Article
Chemistry, Physical
Yufeng Li, Yangyang Yan, Jie Wang, Lidong Li, Fu Tang
Summary: In this study, rod-like silver nanoparticles were successfully prepared in mesoporous silica nanoparticles by a simple method, with tunable optical properties. The resulting gelatin-mixed hydrogel exhibited efficient antibacterial properties due to excellent photothermal performance.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)