A Deep Learning Approach for Predicting Antidepressant Response in Major Depression Using Clinical and Genetic Biomarkers

GWAS-based machine learning approach to predict duloxetine response in major depressive disorder

(2018) Malgorzata Maciukiewicz et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Predicting healthcare trajectories from medical records: A deep learning approach

(2017) Trang Pham et al.   JOURNAL OF BIOMEDICAL INFORMATICS

An Essential Role for the Tetraspanin LHFPL4 in the Cell-Type-Specific Targeting and Clustering of Synaptic GABA A Receptors

(2017) Elizabeth C. Davenport et al.   Cell Reports

Effects of circadian clock genes and health-related behavior on metabolic syndrome in a Taiwanese population: Evidence from association and interaction analysis

(2017) Eugene Lin et al.   PLoS One

Genetic predictors of antipsychotic response to lurasidone identified in a genome wide association study and by schizophrenia risk genes

(2017) Jiang Li et al.   SCHIZOPHRENIA RESEARCH

Transforming growth factor-β signaling pathway-associated genes SMAD2 and TGFBR2 are implicated in metabolic syndrome in a Taiwanese population

(2017) Eugene Lin et al.   Scientific Reports

Identification of 11p14.1-p15.3 deletion probably associated with short stature, relative macrocephaly, and delayed closure of the fontanelles

(2016) Sumito Dateki et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Gene expression inference with deep learning

(2016) Yifei Chen et al.   BIOINFORMATICS

Combining clinical variables to optimize prediction of antidepressant treatment outcomes

(2016) Raquel Iniesta et al.   JOURNAL OF PSYCHIATRIC RESEARCH

A study of single nucleotide polymorphisms of GRIN2B in schizophrenia from Chinese Han population

(2016) Zhenming Guo et al.   NEUROSCIENCE LETTERS

Genome-wide microarray analysis of gene expression profiling in major depression and antidepressant therapy

(2016) Eugene Lin et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Genome-wide investigation of schizophrenia associated plasma Ndel1 enzyme activity

(2016) Ary Gadelha et al.   SCHIZOPHRENIA RESEARCH

Association between the variability of the ABCA13 gene and the risk of major depressive disorder and schizophrenia in the Han Chinese population

(2016) Jianhua Chen et al.   WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY

Association and interaction of APOA5, BUD13, CETP, LIPA and health-related behavior with metabolic syndrome in a Taiwanese population

(2016) Eugene Lin et al.   Scientific Reports

New suggestive genetic loci and biological pathways for attention function in adult attention-deficit/hyperactivity disorder

(2015) Silvia Alemany et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

The combined effect of genetic polymorphisms and clinical parameters on treatment outcome in treatment-resistant depression

(2015) Alexander Kautzky et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Machine learning approaches for integrating clinical and imaging features in late-life depression classification and response prediction

(2015) Meenal J. Patel et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

Genome-wide association studies in pharmacogenomics of antidepressants

(2015) Eugene Lin et al.   PHARMACOGENOMICS

Synaptic P-Rex1 signaling regulates hippocampal long-term depression and autism-like social behavior

(2015) Jun Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Suicidal behavior in the context of disrupted rhythmicity in bipolar disorder—Data from an association study of suicide attempts with clock genes

(2015) Joanna Pawlak et al.   PSYCHIATRY RESEARCH

Whole-Genome Sequencing Suggests Schizophrenia Risk Mechanisms in Humans with 22q11.2 Deletion Syndrome

(2015) Daniele Merico et al.   G3-Genes Genomes Genetics

The International SSRI Pharmacogenomics Consortium (ISPC): a genome-wide association study of antidepressant treatment response

(2015) J M Biernacka et al.   Translational Psychiatry

Genome-Wide Association Study for Autism Spectrum Disorder in Taiwanese Han Population

(2015) Po-Hsiu Kuo et al.   PLoS One

Genome-wide association study of bipolar disorder in Canadian and UK populations corroborates disease loci including SYNE1 and CSMD1

(2014) Wei Xu et al.   BMC Medical Genetics

Bipolar disorder with comorbid binge eating history: A genome-wide association study implicates APOB

(2014) Stacey J. Winham et al.   JOURNAL OF AFFECTIVE DISORDERS

Exploring the associations between genetic variants in genes encoding for subunits of calcium channel and subtypes of bipolar disorder

(2014) Wen-Chi Jan et al.   JOURNAL OF AFFECTIVE DISORDERS

Clock gene variants differentiate mood disorders

(2014) Monika Paulina Dmitrzak-Weglarz et al.   MOLECULAR BIOLOGY REPORTS

A Clinical Risk Stratification Tool for Predicting Treatment Resistance in Major Depressive Disorder

(2013) Roy H. Perlis   BIOLOGICAL PSYCHIATRY

Representation Learning: A Review and New Perspectives

(2013) Y. Bengio et al.   IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE

A Support Vector Machine Approach to Assess Drug Efficacy of Interferon-α and Ribavirin Combination Therapy

(2012) Eugene Lin et al.   Molecular Diagnosis & Therapy

Investigating association of four gene regions (GABRB3, MAOB, PAH, and SLC6A4) with five symptoms in schizophrenia

(2012) Jingchun Sun et al.   PSYCHIATRY RESEARCH

Personalized health care: From theory to practice

(2011) Ralph Snyderman   Biotechnology Journal

Stimulated Gene Expression Profiles as a Blood Marker of Major Depressive Disorder

(2010) Sabine Spijker et al.   BIOLOGICAL PSYCHIATRY

Genome-Wide Association Scan of Trait Depression

(2010) Antonio Terracciano et al.   BIOLOGICAL PSYCHIATRY

The Path to Personalized Medicine

(2010) Margaret A. Hamburg et al.   NEW ENGLAND JOURNAL OF MEDICINE

CYP1A2genetic polymorphisms are associated with treatment response to the antidepressant paroxetine

(2010) Keh-Ming Lin et al.   PHARMACOGENOMICS

Duplication of the SLIT3 Locus on 5q35.1 Predisposes to Major Depressive Disorder

(2010) Joseph T. Glessner et al.   PLoS One

A comparison of classification methods for predicting Chronic Fatigue Syndrome based on genetic data

(2009) Lung-Cheng Huang et al.   Journal of Translational Medicine

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

BNIP-3: A novel candidate for an intrinsic depression-related factor found in NG108-15 cells treated with Hochu-ekki-to, a traditional oriental medicine, or typical antidepressants

(2008) Michihisa Tohda et al.   NEUROSCIENCE RESEARCH

Pharmacogenomics with antidepressants in the STAR*D study

(2008) Eugene Lin et al.   PHARMACOGENOMICS

A Bayesian approach to gene–gene and gene–environment interactions in chronic fatigue syndrome

(2008) Eugene Lin et al.   PHARMACOGENOMICS

PUBLIC HEALTH: A Case Study of Personalized Medicine

(2008) S. H. Katsanis et al.   SCIENCE