Article
Psychiatry
Evyn M. Peters, Kathryn Yates, Jordan DeVylder, Rohit J. Lodhi, Ian Kelleher
Summary: There is an inverse relationship between age and positive psychotic symptoms in patients with psychotic disorders and general population samples. This study found that the decline in borderline personality traits with age may explain this inverse relationship. This finding has important implications for the prevalence of positive psychotic symptoms in both clinical and non-clinical populations.
ACTA PSYCHIATRICA SCANDINAVICA
(2022)
Article
Geriatrics & Gerontology
Aaron Choi, Anthony Martyr, Linda Clare, Jane Fossey, Zunera Khan, Joanne McDermid, Clive Ballard
Summary: Delusions and hallucinations in people with dementia living in nursing homes are associated with poorer quality of life. The effects remain significant even after controlling for other factors. Agitation, anxiety, and depression partially mediate the relationship between each psychotic symptom and quality of life.
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
(2022)
Article
Psychiatry
Abigail C. Wright, Corinne Cather, Kim T. Mueser, Amy Farabaugh, Olga Terechina, Maurizio Fava, Daphne J. Holt
Summary: This study found that subclinical hallucinations are strongly predictive of the severity of delusions in the future, especially when depression is present. However, the severity of hallucinations does not change over time and is not predicted by baseline delusional ideation.
PSYCHIATRY RESEARCH
(2022)
Article
Psychology, Clinical
Ellen S. Herbener, Martin Harrow
Summary: The study found that a small group of individuals with schizophrenia or schizoaffective disorder consistently reported passivity symptoms, while many reported them episodically, and the majority never reported them. The prevalence of passivity symptoms was similar to that of other types of delusions. When present, passivity symptoms were associated with a higher number of additional psychotic symptoms and had some impact on work functioning.
PSYCHOLOGICAL MEDICINE
(2021)
Article
Multidisciplinary Sciences
Leah M. Fleming, Ann Catherine Lemonde, David Benrimoh, James M. Gold, Jane R. Taylor, Ashok Malla, Ridha Joober, Srividya N. Iyer, Martin Lepage, Jai Shah, Philip R. Corlett
Summary: Psychotic disorders are highly heterogeneous, and understanding the relationships between symptoms is crucial for understanding their underlying mechanisms. This study used dimensionality-reduction methods to analyze two unique samples and characterize the patterns of symptom organization. The results revealed clusters of disorganization symptoms, hallucinations/delusions, and negative symptoms, with specific themes and content sometimes co-occurring and sometimes not. These findings have important implications for treatment and research on the neurocomputational and pathophysiological mechanisms underlying delusions and hallucinations.
SCIENTIFIC REPORTS
(2023)
Article
Psychiatry
Cherise Rosen, Martin Harrow, Clara Humpston, Liping Tong, Thomas H. Jobe, Helen Harrow
Summary: Delusions are complex and heterogeneous phenomena that can vary in intensity and stability. This study found that the content of delusions changes over time and that there are significant differences in thought delusions between schizophrenia and affective psychosis. Hallucinations were strongly associated with various types of delusions, suggesting a need for interventions targeting both delusions and hallucinations.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Psychology, Multidisciplinary
Boopala Arul, Daniel Lee, Sarah Marzen
Summary: The study suggests that prior probabilities are more important than observation attributes in distinguishing between real observations and delusions. As observation complexity increases, classification accuracy tends to improve, but accuracy rate decreases with increasing observational complexity if the observer's model is highly inaccurate.
FRONTIERS IN PSYCHOLOGY
(2021)
Review
Psychiatry
Laure Fivel, Marine Mondino, Jerome Brunelin, Frederic Haesebaert
Summary: The processing of basic auditory features in schizophrenia has been extensively studied, with abnormalities found in pitch perception, intensity, duration, and sound localization. However, the relationship between basic auditory processing and symptom severity remains inconclusive. Patients with schizophrenia exhibit deficits in all basic auditory features, indicating the importance of further research and potential remediation strategies.
PSYCHIATRY RESEARCH
(2023)
Article
Psychology, Multidisciplinary
Magdalena Lhotka, Anja Ischebeck, Birgit Helmlinger, Natalia Zaretskaya
Summary: Predictive coding theory proposes that subjective experience is the result of comparing sensory input with top-down predictions. This theory explains various phenomena, including visual illusions, hallucinations, and psychosis. A study tested the connection between these phenomena and found a positive association between pareidolia proneness and delusional ideations, supporting the hierarchical view of predictive processing.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Psychiatry
Pia Jorde Lovgren, Petter Laake, Kjersti Narud, Solveig Klaebo Reitan, Stal Bjorkly
Summary: This study examined 500 forensic reports of legal insanity in Norway from 2009-2018 and found that there were more symptoms recorded from the mental state examination (MSE) than from the mental state at the time of offense (MSO). Delusions and hallucinations were not associated with legal insanity for defendants with schizophrenia. This suggests that a diagnosis of schizophrenia is more important than the symptoms recorded during the offense for determining legal insanity.
Article
Psychology, Clinical
Amy Hardy, Ciaran O'Driscoll, Craig Steel, Mark van der Gaag, David van den Berg
Summary: This study examined the interactions between trauma-related psychological mechanisms and psychotic symptoms using network theory. The results found that trauma-related beliefs had the largest influence in the network, along with hypervigilance, in the pathways from flashbacks to delusions and auditory hallucinations. Further research should explore the role of multiple mediators in trauma-related psychosis.
PSYCHOLOGICAL MEDICINE
(2021)
Article
Clinical Neurology
Amy T. Peters, Xinguo Ren, Katie L. Bessette, Nevita George, Leah R. Kling, Brandon Thies, Amy E. West, Scott A. Langenecker, Ghanshyam N. Pandey
Summary: The study found that inflammatory markers were associated with depressive symptoms and emotion processing in adolescents, with elevated IL-6 being common in depressed adolescents and potentially serving as a specific target for modulating depressive symptoms and emotion processing.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Clinical Neurology
Veera K. Malkki, Tom H. Rosenstrom, Markus M. Jokela, Suoma E. Saarni
Summary: This study examined the impact of depression symptoms on functioning improvement during psychotherapy. The findings showed that changes in depressed mood or hopelessness, sleep problems, fatigue, and lack of interest or pleasure were associated with improved functioning during psychotherapy, while baseline measures of depression symptoms were not related to changes in functioning.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Clinical Neurology
Yexian Zeng, Fan Zhang, Haiyan Liu, Weicheng Li, Yuping Ning, Yanling Zhou
Summary: This study aimed to explore whether the relationship between depressive symptom severity and social-occupational functioning in MDD patients is mediated by psychotic symptom severity and neurocognitive functioning. The results suggest that depressive symptom severity mainly affects the socio-occupational functioning of MDD patients through the mediating effects of psychotic symptoms and neurocognitive functioning.
JOURNAL OF AFFECTIVE DISORDERS
(2023)
Article
Psychiatry
Ellaheh Gohari, Raeanne C. Moore, Colin A. Depp, Robert A. Ackerman, Amy E. Pinkham, Philip D. Harvey
Summary: Schizophrenia participants generate self-reports of their competencies that differ from objective information. Home and being alone are associated with better self-reported functioning, while psychotic symptoms are associated with overestimation.
PSYCHIATRY RESEARCH
(2022)
Article
Behavioral Sciences
Steven M. Silverstein, Michael P. Harms, Cameron S. Carter, James M. Gold, Brian P. Keane, Angus MacDonald, J. Daniel Ragland, Deanna M. Barch
Article
Psychiatry
Steven M. Silverstein, Corinna M. Elliott, Jamie D. Feusner, Brian P. Keane, Deepthi Mikkilineni, Natasha Hansen, Andrea Hartmann, Sabine Wilhelm
PSYCHIATRY RESEARCH
(2015)
Article
Psychiatry
Brian P. Keane, Steven M. Silverstein, Yushi Wang, Matthew W. Roche, Thomas V. Papathomas
SCHIZOPHRENIA RESEARCH
(2016)
Article
Neuroimaging
Tina Gupta, Steven M. Silverstein, Jessica A. Bernard, Brian P. Keane, Thomas V. Papathomas, Andrea Pelletier-Baldelli, Derek J. Dean, Raeana E. Newberry, Ivanka Ristanovic, Vijay A. Mittal
NEUROIMAGE-CLINICAL
(2016)
Article
Psychiatry
Brian P. Keane, Yujia Peng, Docia Demmin, Steve M. Silverstein, Hongjing Lu
PSYCHIATRY RESEARCH
(2018)
Article
Behavioral Sciences
Brian P. Keane, Jamie Joseph, Steven M. Silverstein
Article
Behavioral Sciences
Brian P. Keane, Gennady Erlikhman, Sabine Kastner, Danielle Paterno, Steven M. Silverstein
Article
Psychiatry
Nikoleta Nikitova, Brian P. Keane, Docia Demmin, Steven M. Silverstein, Peter J. Uhlhaas
SCHIZOPHRENIA RESEARCH
(2019)
Article
Psychiatry
Brian P. Keane, Danielle Paterno, Laura P. Crespo, Sabine Kastner, Steven M. Silverstein
PSYCHIATRY RESEARCH
(2019)
Article
Psychology, Clinical
Brian P. Keane, Danielle Paterno, Sabine Kastner, Bart Krekelberg, Steven M. Silverstein
JOURNAL OF ABNORMAL PSYCHOLOGY
(2019)
Article
Psychology, Experimental
Brian P. Keane
Article
Psychology, Clinical
Brian P. Keane, Danielle Paterno, Sabine Kastner, Steven M. Silverstein
JOURNAL OF ABNORMAL PSYCHOLOGY
(2016)
Article
Psychology, Clinical
Vijay A. Mittal, Tina Gupta, Brian P. Keane, Steven M. Silverstein
JOURNAL OF ABNORMAL PSYCHOLOGY
(2015)
Article
Psychology, Mathematical
Brian P. Keane, Sabine Kastner, Danielle Paterno, Steven M. Silverstein
PSYCHONOMIC BULLETIN & REVIEW
(2015)