Review
Psychiatry
Lukas Bergner, Hubertus Himmerich, Kenneth C. Kirkby, Holger Steinberg
Summary: The most common eating disorders are anorexia nervosa, bulimia nervosa, and binge eating disorder. German psychiatric textbooks have described and discussed disordered eating behaviors for the past 200 years, with an emphasis on symptom clusters and differential diagnoses of eating disorders.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Psychiatry
N. Burcu Ozbaran, Zeynep Irem Erbasan, Hazal Yagmur Yilancioglu, Didem Cek, Beguem Yulug Tas, Sibel Helin Tokmak, Tezan Bildik
Summary: This study aims to introduce the subunit service model developed for the multidisciplinary diagnosis and management of eating disorders in the outpatient setting and to evaluate the clinical follow-up of patients.
FRONTIERS IN PSYCHIATRY
(2023)
Article
Psychology, Clinical
Ann F. Haynos, Shirley B. Wang, Sarah Lipson, Carol B. Peterson, James E. Mitchell, Katherine A. Halmi, W. Stewart Agras, Scott J. Crow
Summary: This study compared machine learning (ML) with traditional regression for predicting eating disorder (ED) outcomes, finding that ML models had higher accuracy in predicting all outcomes over 2 years. Important predictors included baseline ED, psychiatric, and demographic characteristics.
PSYCHOLOGICAL MEDICINE
(2021)
Article
Psychiatry
Liron Litmanovich-Cohen, Amit Yaroslavsky, Liron Roni Halevy-Yosef, Tal Shilton, Adi Enoch-Levy, Daniel Stein
Summary: A study of 61 hospitalized ED patients indicates that participating in a post-hospitalization daycare program may improve the 1-year follow-up outcomes for patients, with more achievers of remission. However, patients who do not complete daycare treatment can also maintain a normal BMI one year later. There were no significant differences between the two groups in terms of social functioning, depression, anxiety, and other aspects.
FRONTIERS IN PSYCHIATRY
(2021)
Article
Psychology, Multidisciplinary
Samantha J. Withnell, Abbigail Kinnear, Philip Masson, Lindsay P. Bodell
Summary: This study examined the differences in clinical presentation and treatment outcome between patients with OSFED or threshold EDs. The findings suggest that individuals with OSFED showed largely similar ED psychopathology and similar decreases in symptoms across treatment as individuals diagnosed with threshold EDs.
FRONTIERS IN PSYCHOLOGY
(2022)
Review
Nutrition & Dietetics
Michael J. Butler, Alexis A. Perrini, Lisa A. Eckel
Summary: Alterations in the gut microbiome and immune system may play a role in maintaining and exacerbating eating behavior dysregulation in disorders like anorexia and bulimia, and could potentially serve as biomarkers for increased risk of developing these eating disorders. Research focuses on studying gut dysbiosis, peripheral inflammation, and neuroinflammation in each disorder, as well as exploring data from preclinical rodent models to better understand the biological mechanisms underlying eating disorders. This knowledge is crucial for developing novel and effective treatments for these often difficult-to-treat eating disorders.
Article
Nutrition & Dietetics
Georg Halbeisen, Karsten Braks, Thomas J. Huber, Georgios Paslakis
Summary: This study found that in the same treatment setting, male patients with anorexia showed significant improvements in symptoms, while male patients with BED experienced greater weight loss during treatment. For other eating disorders, the treatment outcomes between men and women were generally similar.
Article
Psychiatry
Tomisin Iwajomo, Susan J. Bondy, Claire de Oliveira, Patricia Colton, Kathryn Trottier, Paul Kurdyak
Summary: Individuals diagnosed with eating disorders in hospital settings have a five to seven times higher mortality rate compared to the overall population, with males experiencing higher mortality rates than females across all age groups.
BRITISH JOURNAL OF PSYCHIATRY
(2021)
Article
Clinical Neurology
Claire E. Cusack, Irina A. Vanzhula, Cheri A. Levinson
Summary: This study used network analysis to examine the structure of symptoms and somatic concerns in individuals with eating disorders (EDs). The results showed that heightened sensitivity to somatic concerns played a central role in the symptom network and may contribute to the maintenance of ED symptoms. The findings have implications for the assessment and treatment of EDs.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Review
Medicine, General & Internal
Kacper Nijakowski, Jakub Jankowski, Dawid Gruszczynski, Anna Surdacka
Summary: This systematic review found a relationship between eating disorders, particularly bulimia nervosa, and dental erosion. Individuals with bulimia nervosa were over 10 times more likely to experience tooth erosion, and self-induced vomiting increased the odds of tooth erosion by over 16 times.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Clinical Neurology
Abigail Calder, Seline Mock, Nicole Friedli, Patrick Pasi, Gregor Hasler
Summary: Eating disorders are serious illnesses with high mortality rates and comorbidity with other mental health problems. Psychedelic-assisted therapy has shown potential in treating comorbidities of eating disorders, such as mood disorders, PTSD, and substance use disorders. This review summarizes preliminary data on the efficacy of psychedelic-assisted therapy in anorexia nervosa, bulimia nervosa, and binge eating disorder, and discusses potential therapeutic mechanisms. It suggests that psychedelic-assisted therapy may be effective in treating anorexia nervosa and bulimia nervosa, while data on binge eating disorder is limited. The therapy may improve body image beliefs, normalize reward processing, promote cognitive flexibility, and facilitate trauma processing, as well as addressing common therapeutic factors. Safety concerns and future research recommendations are also discussed.
EUROPEAN NEUROPSYCHOPHARMACOLOGY
(2023)
Article
Psychiatry
Andreas Birgegard, Emma Forsen Mantilla, Lisa Dinkler, Elin Hedlund, Androula Savva, Henrik Larsson, Cynthia M. Bulik
Summary: The validity of diagnoses in the Swedish National Patient Register (NPR) is crucial for supporting research and policy recommendations. A comparison with the integrated National Quality Registers (QR) showed that the ED diagnoses in NPR have acceptable validity, providing valuable data for research purposes.
JOURNAL OF PSYCHIATRIC RESEARCH
(2022)
Review
Psychology, Clinical
Katja Kurnik Mesaric, Ziga Damjanac, Tjas Debeljak, Jana Kodric
Summary: This study conducted a systematic literature review to investigate the role of psychoeducation in the treatment of eating disorders in children and adolescents. The results indicated that psychoeducation is an effective intervention, leading to weight gain, a decrease in eating disorder symptoms, and a reduction in caregiver burden. However, more randomized controlled trials are needed to determine the effectiveness of psychoeducation in the treatment of eating disorders.
EUROPEAN EATING DISORDERS REVIEW
(2023)
Article
Agriculture, Dairy & Animal Science
Ana Myriam Lavin-Perez, Cristina Martin-Sanchez, Beatriz Martinez-Nunez, Luis Lucio Lobato-Rincon, Santos Villafaina, Israel Gonzalez-Garcia, Ana Mata-Cantero, Montserrat Graell, Eugenio Merellano-Navarro, Daniel Collado-Mateo
Summary: This study aims to evaluate the effects of dog-assisted therapy on adolescents with eating disorders, with significant improvements expected based on the known benefits of animal-assisted therapies in different populations.
Article
Psychology, Multidisciplinary
Bente Sommerfeldt, Finn Skarderud, Ingela Lundin Kvalem, Kjersti S. Gulliksen, Arne Holte
Summary: Pregnancy is a vulnerable period for women with a history of eating disorders. Our study found that almost all participants experienced worsening or relapse of their disorder during pregnancy.
FRONTIERS IN PSYCHOLOGY
(2022)
Review
Psychology, Developmental
Marie Lyngdrup Kjeldbjerg, Loa Clausen
Summary: The objective of this study was to estimate the prevalence of binge-eating disorder (BED) and subclinical BED in children and adolescents. The results showed that the prevalence of BED in children and adolescents was 1.32% and the prevalence of subclinical BED was 3.0%. The study found that BED is as common in this age group as anorexia nervosa and bulimia nervosa.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Article
Psychology, Clinical
Benjamin Mac Donald, Cynthia M. Bulik, Janne T. Larsen, Anders H. Carlsen, Loa Clausen, Liselotte Petersen
Summary: This study explored the utilization patterns of involuntary treatment (IT) events in patients with anorexia nervosa (AN), and identified factors associated with subsequent IT utilization and restraint. The study found that IT utilization peaked in the initial few years following the index admission, and a small percentage of patients accounted for a majority of the IT events. Factors such as female sex, lower age, and previous admissions with psychiatric disorders were associated with increased IT rates and restraint. It is important to explore alternative approaches to treatment that can reduce the need for IT in these patients.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychiatry
Loa Clausen, Birgitte D. Semark, Janne Helverskov, Cynthia M. Bulik, Liselotte V. Petersen
Summary: Pharmacotherapy is frequently used in the treatment of anorexia nervosa (AN) despite the lack of recommended medications. This study examines the nationwide use of pharmacotherapy in AN patients both before and after their first diagnosis. The results highlight the extensive use of medication in AN patients, particularly in the categories of alimentary and psychopharmacological medication.
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2023)
Article
Psychiatry
Pernille Byrial, Lene Nyboe, Per Hove Thomsen, Loa Clausen
Summary: This study aimed to compare fine and gross motor function in adolescents with schizophrenia and controls using age-adjusted tests over a 2-year period. The results showed significant differences in most motor function measures between schizophrenia patients and controls. This study highlights the importance of assessing motor function in adolescents with schizophrenia.
EARLY INTERVENTION IN PSYCHIATRY
(2023)
Article
Psychiatry
Bo Skytte Kaa, Johanne Mathilde Nymark Bunemann, Loa Clausen
Summary: This study describes a new stepped-care outpatient treatment for anorexia nervosa, which combines group and individual therapy with a focus on normalizing eating and weight. The treatment showed significant improvements in outcome measures at 6 and 12 months, with higher BMI and greater BMI increase compared to other specialized treatments.
NORDIC JOURNAL OF PSYCHIATRY
(2023)
Article
Rehabilitation
Pernille Byrial, Loa Clausen, Lene Nyboe
Summary: This study compared the ability of MABC-2 and BOT-2 to assess adolescent motor performance and distinguish between those with and without schizophrenia. The results showed that both tests were effective in distinguishing adolescents with schizophrenia from the control group, but BOT-2 provided more detailed information. There was a strong association between the two tests and moderate agreement in identifying risk or scoring below average. Only sex had an influence on MABC-2 scores.
PHYSIOTHERAPY RESEARCH INTERNATIONAL
(2023)
Article
Microbiology
Yong Fan, Rene Klinkby Stoving, Samar Berreira Ibraim, Tuulia Hyotylainen, Florence Thirion, Tulika Arora, Liwei Lyu, Evelina Stankevic, Tue Haldor Hansen, Pierre Dechelotte, Tim Sinioja, Oddny Ragnarsdottir, Nicolas Pons, Nathalie Galleron, Benoit Quinquis, Florence Levenez, Hugo Roume, Gwen Falony, Sara Vieira-Silva, Jeroen Raes, Loa Clausen, Gry Kjaersdam Telleus, Fredrik Backhed, Matej Oresic, S. Dusko Ehrlich, Oluf Pedersen
Summary: This study investigated the role of gut microbiota in the pathogenesis of anorexia nervosa (AN) by analyzing metagenomics and metabolomics data from AN patients and healthy females. The results showed that AN patients exhibited alterations in gut microbiota composition and function, as well as increased levels of metabolites associated with reduced food intake. Microbiota transplantation experiments further confirmed the contribution of gut microbiota to AN behavior.
NATURE MICROBIOLOGY
(2023)
Article
Emergency Medicine
Marie Louise Thise Rasmussen, Kirsten Lomborg, Kasper Karmark Iversen, Hanne Konradsen
Summary: This study explored the extent of patients' involvement in discharge planning in acute care and how patient involvement in decisions regarding discharge planning is managed in clinical practice. The study found that two out of three patients did not experience being involved in decisions regarding emergency department discharge, and the organizational structure in clinical practice limited patient involvement. It is important to uncover opportunities and initiatives to increase patient involvement in decisions in the future.
EMERGENCY MEDICINE INTERNATIONAL
(2023)
Article
Psychology, Clinical
Benjamin Mac Donald, Sanna A. Gustafsson, Cynthia M. Bulik, Loa Clausen
Summary: This study explored the experiences and perspectives of patients with multiple involuntary treatment events in order to understand involuntary treatment and potentially inform treatment. The results showed that patients with anorexia nervosa and multiple involuntary treatment events experience a life of coercion, both internally from the illness itself and externally from involuntary treatment. Involuntary treatment can aid in the internal battle against anorexia nervosa and perspectives on involuntary treatment can change over time. However, it can also have negative effects on patients, such as feelings of being hunted or assaulted. Clinicians should be aware of these potential negative effects and only use involuntary treatment in life-threatening situations.
JOURNAL OF EATING DISORDERS
(2023)
Article
Nursing
Annesofie L. Jensen, Liv Marit Valen Schougaard, Tinne Laurberg, Troels Krarup Hansen, Kirsten Lomborg
Summary: We conducted interviews with 36 patients with type 1 diabetes who used DiabetesFlex Care and found that the system changed their perspectives on living with diabetes, encouraging more involvement in their own care and improving conversations with healthcare professionals. The ability to choose appointment formats and cancel unnecessary appointments was also appreciated. DiabetesFlex Care is a flexible and inclusive health service that enables patients to take more responsibility for their own diabetes management and supports user involvement and self-management.
SCANDINAVIAN JOURNAL OF CARING SCIENCES
(2023)
Article
Endocrinology & Metabolism
Mette Soeby, Sigrid Bjerge Gribsholt, Loa Clausen, Bjorn Richelsen
Summary: Researchers found that patients with anorexia nervosa (AN) had a 46% increased risk of any fracture up to 40 years after diagnosis. While there was no overall increased risk in males, both males and females with AN had a particularly high risk of site-specific fractures in the spine and femur. Fracture risk decreased in recent decades, possibly due to the diagnosis and intervention of less severe cases of AN.
JOURNAL OF BONE AND MINERAL RESEARCH
(2023)
Article
Nursing
Marie Louise Thise Rasmussen, Kirsten Lomborg, Hanne Konradsen
Summary: Background: Patients in the emergency department are less involved in making decisions than they would like to be, and more research is needed on the healthcare professional's perspective of involving patients in decisions. Aim: To explore the challenges faced by healthcare professionals in involving patients in discharge decisions in the emergency department. Method: Five focus group interviews were conducted with nurses and physicians, and data were analyzed using content analysis. Findings: Healthcare professionals experienced a lack of choice to offer patients, due to the need to prioritize department routines and manage diverse patient characteristics. They also wanted to protect patients from limited options. Conclusion: Healthcare professionals perceived patient involvement as incompatible with professionalism, and new initiatives are needed to improve communication with patients for decision-making regarding discharge.
INTERNATIONAL EMERGENCY NURSING
(2023)
Article
Orthopedics
Hanne Mainz, Lone Frandsen, Peter Fauno, Kirsten Lomborg, Martin Lind
Summary: The study aimed to investigate the impact of exposure to a patient decision aid (PDA) on the proportion of patients selecting non-surgical or surgical treatments after ACL injuries, and whether exposure to a PDA affected the proportion of patients switching from non-surgical to surgical treatment within the first year. A consecutive case series was conducted, comparing the proportions of surgery and non-surgery before and after patients' exposure to a PDA. The results showed that exposure to the PDA did not significantly alter the proportions of treatment selection or switching within the first year.
JOURNAL OF EXPERIMENTAL ORTHOPAEDICS
(2023)
Article
Multidisciplinary Sciences
L. E. Joensen, P. Lindgreen, K. Olesen, M. Nygaard, D. Hessler, H. U. Andersen, J. O. Christensen, U. L. Kielgast, K. Norgaard, U. Pedersen-Bjergaard, I. Willaing
Summary: The aim of this study was to validate the Type 1 Diabetes Distress Scale (T1-DDS) in a large sample of adults with Type 1 diabetes (T1D) in Denmark. The results showed that the T1-DDS has good content and acceptable construct validity, and can assess the level of diabetes distress among adults with T1D.
Article
Psychiatry
Caroline Bruun Abild, Annesofie Lunde Jensen, Rikke Bjerre Lassen, Esben Thyssen Vestergaard, Jens Meldgaard Bruun, Kurt Kristensen, Rene Klinkby Stoving, Loa Clausen
Summary: This paper explores the perspectives of patients with type 1 diabetes on the Diabetes Eating Problem Survey Revised (DEPS-R), a screening questionnaire for disordered eating and eating disorders. The study finds that DEPS-R is clinically relevant and accepted by adolescents with type 1 diabetes, and suggests potential updates for certain items in the questionnaire.
EATING AND WEIGHT DISORDERS-STUDIES ON ANOREXIA BULIMIA AND OBESITY
(2023)