Total syntheses of pyrroloazocine indole alkaloids: challenges and reaction discovery

Highly Enantioselective Copper- and Iron-Catalyzed Intramolecular Cyclopropanation of Indoles

(2017) Huan Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of (±)-Grandilodine B

(2017) Chunyu Wang et al.   ORGANIC LETTERS

Total Syntheses of (+)-Grandilodine C and (+)-Lapidilectine B and Determination of their Absolute Stereochemistry

(2016) Masaya Nakajima et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Concise Total Synthesis of Lundurines A–C Enabled by Gold Catalysis and a Homodienyl Retro-Ene/Ene Isomerization

(2016) Mariia S. Kirillova et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Studies of a Diazo Cyclopropanation Strategy for the Total Synthesis of (−)-Lundurine A

(2015) Hong-Xiu Huang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric Total Synthesis of (−)-Lundurine B and Determination of Its Absolute Stereochemistry

(2015) Masaya Nakajima et al.   Chemistry-An Asian Journal

Kinetic or Dynamic Control on a Bifurcating Potential Energy Surface? An Experimental and DFT Study of Gold-Catalyzed Ring Expansion and Spirocyclization of 2-Propargyl-β-tetrahydrocarbolines

(2015) Lei Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric synthesis and biological activities of natural product (+)-balasubramide and its derivatives

(2015) Jun Li et al.   NATURAL PRODUCT RESEARCH

A general route to the synthesis of indoloazocines using allyl bromides prepared from Morita–Baylis–Hillman adducts

(2015) Garima Pandey et al.   TETRAHEDRON LETTERS

Directed synthesis of 2-spiroindolines from indole derivatives by formic acid-induced N-acyliminium ion-conjugated diene spirocyclization

(2015) Hideki Abe et al.   TETRAHEDRON LETTERS

Diverse Applications of Nitrones for the Synthesis of Heterocyclic Compounds

(2015) Laura L. Anderson   Asian Journal of Organic Chemistry

Enantioselective Michael/aza-Michael/Cyclization Organocascade to Tetracyclic Spiroindolines: Concise Total Synthesis of Kopsinine and Aspidofractine

(2014) Xiaoyu Wu et al.   ADVANCED SYNTHESIS & CATALYSIS

Total Synthesis of (−)-Lundurine A and Determination of its Absolute Configuration

(2014) Shuaijiang Jin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Corrigendum: A Concise and Versatile Synthesis of Alkaloids fromKopsia tenuis: Total Synthesis of (±)-Lundurine A and B

(2014) Shigeru Arai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Concise and Versatile Synthesis of Alkaloids fromKopsia tenuis: Total Synthesis of (±)-Lundurine A and B

(2014) Shigeru Arai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Azocinoindole Synthesis by a Gold(I)-Catalyzed Ring Expansion of 2-Propargyl-β-Tetrahydrocarboline

(2014) Lei Zhang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Total Synthesis of (±)-Lundurine B

(2014) Masaki Hoshi et al.   ORGANIC LETTERS

Synthesis of pseudo-indoxyl derivatives via sequential Cu-catalyzed SNAr and Smalley cyclization

(2013) Yogesh Goriya et al.   CHEMICAL COMMUNICATIONS

CuO/SiO2 as a simple, effective and recoverable catalyst for alkylation of indole derivatives with diazo compounds

(2013) José M. Fraile et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of the indoloazocine derivatives from a chiral indol amide-stabilized sulfur ylide

(2013) Maira Juárez-Calderón et al.   TETRAHEDRON LETTERS

Transition-metal-free approach to synthesis of indolines from N-(ortho-chloromethyl)aryl amides and iodonium ylides

(2013) Hui Huang et al.   TETRAHEDRON LETTERS

Synthesis of Azocino[5,4-b]indolesviaGold-Catalyzed Intramolecular Alkyne Hydroarylation

(2012) Vsevolod A. Peshkov et al.   ADVANCED SYNTHESIS & CATALYSIS

Total Synthesis of (−)-Kopsinine by an Asymmetric One-Pot [N+2+3] Cyclization

(2012) Shingo Harada et al.   Chemistry-An Asian Journal

Conformational, steric and electronic effects on the site- and chemoselectivity of the metal-catalyzed reaction of N-bis(trimethylsilyl)methyl, N-(2-indolyl)methyl α-diazoamides

(2012) Bao Zhang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthetic Studies toward Lapidilectine-Type Kopsia Alkaloids

(2012) Erica E. Schultz et al.   ORGANIC LETTERS

Enantioselective Cyclopropanation of Indoles: Construction of All-Carbon Quaternary Stereocenters

(2012) Gülsüm Özüduru et al.   ORGANIC LETTERS

Grandilodines A−C, Biologically Active Indole Alkaloids fromKopsia grandifolia

(2011) Wai-Sum Yap et al.   JOURNAL OF NATURAL PRODUCTS

Collective synthesis of natural products by means of organocascade catalysis

(2011) Spencer B. Jones et al.   NATURE

Photochemical and thermal cyclizations of 4-(2-azidophenyl)-3,4-dihydropyrimidin-2-ones for the synthesis of 4-methylenepyrimidino[5,4-b]indol-2-ones

(2010) Yu-wei Ren et al.   TETRAHEDRON LETTERS

Highly Efficient Asymmetric Epoxidation of Electron-Deficient α,β-Enones and Related Applications to Organic Synthesis

(2009) Changwu Zheng et al.   ADVANCED SYNTHESIS & CATALYSIS

Stereoselective Synthesis of (+)-Aspidofractinine

(2009) David Gagnon et al.   JOURNAL OF ORGANIC CHEMISTRY

Efficient Approach to Androstene-Fused Arylpyrazolines as Potent Antiproliferative Agents. Experimental and Theoretical Studies of Substituent Effects on BF3-Catalyzed Intramolecular [3 + 2] Cycloadditions of Olefinic Phenylhydrazones

(2009) Éva Frank et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient Synthesis of the Indoloazocine Framework via Intramolecular Alkyne Carbocyclization

(2009) Pavel A. Donets et al.   ORGANIC LETTERS

Synthesis of the tetracyclic core skeleton of the lundurines by a gold-catalyzed cyclization

(2009) Catalina Ferrer et al.   TETRAHEDRON

Metal-catalyzed reaction of N-(2-indolyl)methyl, N-bis(trimethylsilyl)methyl diazoamides: an entry into the β-carboline ring system

(2008) Bao Zhang et al.   CHEMICAL COMMUNICATIONS

Synthesis of methyl 4,6-O-benzylidene-2,3-dideoxy-5-thio-β-dl-threo-hex-2-enopyranoside via hetero-Diels–Alder reaction and unusual stabilities of 1,5-anhydro-4,6-O-benzylidene 2,3-dideoxy-5-thio-dl-threo-hex-2-enitol

(2008) Yuhya Watanabe et al.   TETRAHEDRON

An interrupted Ugi reaction enables the preparation of substituted indoxyls and aminoindoles

(2008) John S. Schneekloth et al.   TETRAHEDRON

Synthesis of spirocyclopentene-indolines by intramolecular alkylidine insertion reactions

(2008) Christopher J. Whipp et al.   TETRAHEDRON LETTERS