Catalytic approaches to assemble cyclobutane motifs in natural product synthesis

Recent Applications of Rh- and Pd-Catalyzed C(sp3 )-H Functionalization in Natural Product Total Synthesis

(2017) Patrick B. Brady et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthetic Study of Phainanoids. Highly Diastereoselective Construction of the 4,5-Spirocycle via Palladium-Catalyzed Intramolecular Alkenylation

(2017) Jiaxin Xie et al.   ORGANIC LETTERS

A Mixed-Ligand Chiral Rhodium(II) Catalyst Enables the Enantioselective Total Synthesis of Piperarborenine B

(2016) Robert A. Panish et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Advances in the Synthesis of Cyclobutanes by Olefin [2 + 2] Photocycloaddition Reactions

(2016) Saner Poplata et al.   CHEMICAL REVIEWS

Enantioselective Construction of Cyclobutanes: A New and Concise Approach to the Total Synthesis of (+)-Piperarborenine B

(2016) Jiang-Lin Hu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Collaborative Total Synthesis: Routes to (±)-Hippolachnin A Enabled by Quadricyclane Cycloaddition and Late-Stage C–H Oxidation

(2016) Monica E. McCallum et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Total Synthesis of (+)-Psiguadial B

(2016) Lauren M. Chapman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Emergence of diversity and stereochemical outcomes in the biosynthetic pathways of cyclobutane-centered marine alkaloid dimers

(2016) Mehdi A. Beniddir et al.   NATURAL PRODUCT REPORTS

Trends in applying C–H oxidation to the total synthesis of natural products

(2016) Yuanyou Qiu et al.   NATURAL PRODUCT REPORTS

Attractive natural products with strained cyclopropane and/or cyclobutane ring systems

(2016) Yao-Yue Fan et al.   Science China-Chemistry

Cyclobutane and Cyclobutene Synthesis: Catalytic Enantioselective [2+2] Cycloadditions

(2015) Yao Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Scopariusicides, Novel Unsymmetrical Cyclobutanes: Structural Elucidation and Concise Synthesis by a Combination of Intermolecular [2 + 2] Cycloaddition and C–H Functionalization

(2015) Min Zhou et al.   ORGANIC LETTERS

Total Synthesis of (±)-Hippolachnin A

(2014) Stefan A. Ruider et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Boc Amines to Oxazolidinones via Pd(II)/Bis-sulfoxide/Brønsted Acid Co-Catalyzed Allylic C–H Oxidation

(2014) Thomas J. Osberger et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Terminal Olefins to Chromans, Isochromans, and Pyrans via Allylic C–H Oxidation

(2014) Stephen E. Ammann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phainanoids A–F, A New Class of Potent Immunosuppressive Triterpenoids with an Unprecedented Carbon Skeleton from Phyllanthus hainanensis

(2014) Yao-Yue Fan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Naturally occurring bioactive Cyclobutane-containing (CBC) alkaloids in fungi, fungal endophytes, and plants

(2014) Valery M. Dembitsky   PHYTOMEDICINE

Antifungal Drug Development: Challenges, Unmet Clinical Needs, and New Approaches

(2014) T. Roemer et al.   Cold Spring Harbor Perspectives in Medicine

Hippolachnin A, a New Antifungal Polyketide from the South China Sea Sponge Hippospongia lachne

(2013) Shu-Juan Piao et al.   ORGANIC LETTERS

Total Synthesis and Structural Revision of the Piperarborenines: When Photochemistry Meets CH Activation

(2012) Frédéric Frébault et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Sequential C sp 3H Arylation and Olefination: Total Synthesis of the Proposed Structure of Pipercyclobutanamide A

(2012) Will R. Gutekunst et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereoselective Preparation of Cyclobutanes with Four Different Substituents: Total Synthesis and Structural Revision of Pipercyclobutanamide A and Piperchabamide G

(2012) Renhe Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

CH Activation: A Complementary Tool in the Total Synthesis of Complex Natural Products

(2012) David Y.-K. Chen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Antifungal Drug Discovery: Something Old and Something New

(2012) Arielle Butts et al.   PLoS Pathogens

Total Synthesis and Structural Revision of the Piperarborenines via Sequential Cyclobutane C–H Arylation

(2011) Will R. Gutekunst et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Versatile and Stereoselective Synthesis of Functionalized Cyclobutenes

(2010) Frédéric Frébault et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Auxiliary-Assisted Palladium-Catalyzed Arylation and Alkylation of sp2and sp3Carbon−Hydrogen Bonds

(2010) Dmitry Shabashov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Psiguadials A and B, Two Novel Meroterpenoids with Unusual Skeletons from the Leaves ofPsidium guajava

(2010) Meng Shao et al.   ORGANIC LETTERS

Hepatoprotective amide constituents from the fruit of Piper chaba: Structural requirements, mode of action, and new amides

(2009) Hisashi Matsuda et al.   BIOORGANIC & MEDICINAL CHEMISTRY