Article
Clinical Neurology
Ari R. Joffe
Summary: I argue that death is irreversible and not merely permanent because even though a state could be reversed, the decision has been made not to attempt this reversal. Four reasons are given to support this argument, including the inability to return from death and the implications on culpability. Four objections are considered and rejected, and the author concludes that irreversible loss of circulation is the criterion for biological death.
Article
Computer Science, Interdisciplinary Applications
Xianzheng Huang, Hongmei Zhang
Summary: Hypotheses testing procedures based on quadratic inference functions are proposed to test differences in structure and strength of associations between nodes in two Gaussian Bayesian networks. Bootstrap procedures are used to estimate p-values and investigate the operating characteristics of these testing procedures in simulation experiments. Additionally, the proposed methods are applied to flow cytometry data from a designed experiment, and data of bile acids from an observational study in the Alzheimer's Disease Neuroimaging Initiative.
COMPUTATIONAL STATISTICS & DATA ANALYSIS
(2021)
Article
Engineering, Biomedical
Zhenhao Zhao, Chufeng Li, Yiwen Zhang, Chao Li, Yongchao Chu, Xuwen Li, Peixin Liu, Hongyi Chen, Yu Wang, Boyu Su, Qinjun Chen, Tao Sun, Chen Jiang
Summary: The poor outcomes of triple-negative breast cancer brain metastases are due to the lack of effective therapies. Immunotherapy has limitations for TNBC brain metastases due to non-immunogenicity of tumors and strong immunosuppressive environment. This study proposed a cocktail-like therapeutic strategy of microenvironment regulation-chemotherapy-immune synergistic sensitization and developed reduction-sensitive immune microenvironment regulation nano-materials (SIL@T). SIL@T showed dual immunomodulatory functions and provided a promising immune synergistic therapy strategy for breast cancer brain metastases.
BIOACTIVE MATERIALS
(2023)
Article
Multidisciplinary Sciences
Valen E. Johnson, Sandipan Pramanik, Rachael Shudde
Summary: Bayes factors provide a direct measure of the support that data give to competing hypotheses. Using Bayes factor functions, hypothesis tests can be easily summarized without relying on arbitrary P-value thresholds for statistical significance.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Review
Automation & Control Systems
Sabine Mondie, Alexey Egorov, Marco A. Gomez
Summary: The paper provides an overview of stability conditions for time-delay systems using the Lyapunov matrix. It presents detailed results and proofs for systems with multiple delays. The state of the art, ongoing research, and potential extensions to other classes of delay systems are discussed.
ANNUAL REVIEWS IN CONTROL
(2022)
Review
Anesthesiology
Joel Neves Briard, Roy Nitulescu, Emile Lemoine, Polina Titova, Lauralyn McIntyre, Shane W. English, Greg Knoll, Sam D. Shemie, Claudio Martin, Alexis F. Turgeon, Francois Lauzier, Dean A. Fergusson, Michael Chasse
Summary: The purpose of this study was to synthesize the sensitivity and specificity of commonly used ancillary tests for death determination by neurologic criteria. The results showed that there is significant heterogeneity in the diagnostic accuracy of ancillary tests, and most estimates have high statistical uncertainty. High-quality studies are needed to validate the accuracy of ancillary tests for death determination by neurologic criteria.
CANADIAN JOURNAL OF ANESTHESIA-JOURNAL CANADIEN D ANESTHESIE
(2023)
Article
Computer Science, Interdisciplinary Applications
Koosha Khorramian, Fadi Oudah
Summary: Reducing the cost of calculation without compromising the accuracy of the solution can be achieved using surrogate models like active learning Kriging (AK) reliability methods. This study aims to enhance the accuracy and efficiency of AK reliability analysis by developing new learning functions, stopping criteria, and a method for selecting the next candidate for updating the design of experiments (DoE) in the learning process.
STRUCTURAL AND MULTIDISCIPLINARY OPTIMIZATION
(2023)
Article
Mathematics
Benoit Collins, Tobias Mai, Akihiro Miyagawa, Felix Parraud, Sheng Yin
Summary: This paper investigates the convergence of the spectral distribution of noncommutative rational functions in independent random matrix models using free probability. It answers an open question by Roland Speicher and demonstrates that the approximation of self-adjoint noncommutative rational functions by generic matrices can be upgraded in terms of distribution convergence.
MATHEMATISCHE ANNALEN
(2022)
Article
Cell Biology
Rajarshi Chakrabarti, Tak Shun Fung, Taewook Kang, Pieti W. Elonkirjo, Anu Suomalainen, Edward J. Usherwood, Henry N. Higgs
Summary: Chakrabarti, Fung et al. demonstrate that actin polymerization dependent on the Arp2/3 complex is necessary for the rapid increase of glycolysis under conditions that compromise mitochondrial function. They also suggest that acute damage-induced actin (ADA) is linked to the glycolytic activation upon mitochondrial damage.
JOURNAL OF CELL BIOLOGY
(2022)
Article
Psychology, Multidisciplinary
Mathilde Chevignard, Amanda Guerra, Rafika Fliss, Lucie Salah, Emmanuelle Pineau, Pauline Notteghem, Jeanne Roche, Caroline Huon, Agata Krasny Pacini, Didier Le Gall, Nathalie Fournet, Jean-Luc Roulin, Arnaud Roy
Summary: Executive functioning is severely affected following moderate-to-severe childhood TBI and should be assessed using a combination of developmentally appropriate neuropsychological tests and behavioral ratings to gain a comprehensive understanding of children's executive functions.
FRONTIERS IN PSYCHOLOGY
(2023)
Article
Mathematics, Applied
Jakob Reiffenstein
Summary: This article presents the characterization of Herglotz-Nevanlinna functions and the matrix version of the Hermite-Biehler Theorem. These results are of great significance in studying the properties of functions.
JOURNAL OF MATHEMATICAL ANALYSIS AND APPLICATIONS
(2022)
Article
Engineering, Marine
Oleksandr Kanifolskyi, Valerio Ruggiero
Summary: The need for research arises when there is a discrepancy between theoretical and practical data. Different classification societies have different rules regarding yacht navigation areas and wave heights. In practice, it is important to study the ship's wave height limits, the wave height at which wetness occurs, the relationship between design accelerations and technical characteristics, the distance between emergency and rescue ships, and the minimum time required for assistance.
JOURNAL OF MARINE SCIENCE AND ENGINEERING
(2022)
Article
Construction & Building Technology
Shilang Xu, Qinghua Li, Yao Wu, Lixin Dong, Yao Lyu, Hans W. Reinhardt, Christopher K. Y. Leung, Gonzalo Ruiz, Shailendra Kumar, Shaowei Hu
Summary: This recommendation specifies standard testing methods for determining the double-K criterion for Mode I crack propagation in concrete, including geometry for specimens, fabrication of specimens, testing machine, load transmission system, and supports, measuring instruments, determination of initial cracking load P-ini, determination of measured maximum load P-max and initial compliance c(i), calculation methods for wedge-splitting test and three-point bending beam test, as well as the testing results and testing report forms. By using these methods, the measured fracture parameters of double-K criterion can describe the onset of cracking, unstable cracking, and failure in concrete structures.
MATERIALS AND STRUCTURES
(2021)
Article
Soil Science
Mirjam S. Breure, Elise Van Eynde, Bas Kempen, Rob N. J. Comans, Ellis Hoffland
Summary: This study explored the extraction mechanisms of different soil testing methods, derived transfer functions between P and K variables, and evaluated their application in predicting soil fertility and maize yield using the QUEFTS model. The study found that the transfer functions performed well in tropical soils, with minor effects on yield predictions.
Article
Computer Science, Artificial Intelligence
Marc Goerigk, Romain Guillaume, Adam Kasperski, Pawel Zielinski
Summary: This paper investigates an optimization problem with uncertain objective function coefficients. The uncertainty is described by a discrete scenario set. The concept of belief function is used to define admissible probability distributions over the scenario set. The generalized Hurwicz criterion is applied to compute a solution. The complexity of the problem is explored and exact and approximation methods are proposed.
INTERNATIONAL JOURNAL OF APPROXIMATE REASONING
(2023)