Article
Microbiology
Edyta B. Hendiger, Marcin Padzik, Ines Sifaoui, Maria Reyes-Batlle, Atteneri Lopez-Arencibia, Diana Zyskowska, Marta Grodzik, Anna Pietruczuk-Padzik, Jacek Hendiger, Gabriela Oledzka, Lidia Chomicz, Jose E. Pinero, Jacob Lorenzo-Morales
Summary: Acanthamoeba keratitis is a severe corneal infection that can be effectively reduced by incorporating silver nanoparticles into contact lens solutions without increasing cytotoxicity.
Article
Microbiology
Yu-Jen Wang, Sung-Chou Li, Wei-Chen Lin, Fu-Chin Huang
Summary: This study reveals the abundant anaerobic Gram-positive rods present in severe keratitis isolate and characterizes the association between Acanthamoeba and ocular flora in AK progression. Further analysis shows that Blautia producta is positively correlated with the disease course, while Bacteroides ovatus is abundant in early-stage keratitis isolates.
Article
Microbiology
Marcin Padzik, Lidia Chomicz, Julita Bluszcz, Karolina Maleszewska, Jaroslaw Grobelny, David Bruce Conn, Edyta B. Hendiger
Summary: Acanthamoeba spp. can cause Acanthamoeba keratitis, particularly in contact lens wearers. It has been found that silver nanoparticles combined with tannic acid-modified contact lens solutions can enhance their anti-adhesion activity with low cytotoxicity.
Article
Microbiology
Allison Campolo, Brian Patterson, Esther Lara, Paul Shannon, Monica Crary
Summary: Acanthamoeba keratitis is a challenging infection of the cornea, and understanding the behavior of Acanthamoebae during contact lens use and disinfection can provide insights into their colonization and the efficacy of contact lens care solutions. In this study, Acanthamoeba behavior during and after disinfection with different contact lens care solutions was examined. The results showed that all contact lens care solutions significantly impacted Acanthamoeba motility, with the solution containing PHMB showing the most effectiveness. Post-disinfection, Acanthamoebae were observed to regain motility and travel considerable distances, posing a potential risk to ocular health.
Article
Microbiology
Anna C. Randag, Lieke de Kroon, Henny Otten, Cindy Arias Claro-Handgraaf, Barbara Schimmer, Titia Kortbeek, Jeroen van Rooij, Foekje F. Stelma
Summary: This study investigates the effectiveness of contact lens solutions available on the Dutch market against Acanthamoeba castellanii and Acanthamoeba polyphaga. The results show that only a few solutions provide sufficient effectiveness against trophozoites, but none against cysts. These findings underline the importance of proper hygiene when handling contact lenses.
Review
Ophthalmology
Lauren Jeang, Sonal S. Tuli
Summary: This review examines the current literature and practice patterns of antimicrobial therapy for contact lens-related microbial keratitis (CLMK). The use of topical antimicrobials is the mainstay of treatment for corneal ulcers, but bacterial, fungal, and acanthamoeba ulcers present different challenges due to resistance and the lack of effective topical medications. Novel therapies and diagnostic procedures offer hope for improved treatment outcomes. Contact lens-associated microbial keratitis is a significant health issue that can cause vision loss.
CURRENT OPINION IN OPHTHALMOLOGY
(2022)
Article
Ophthalmology
Fiona Stapleton, Chris H. L. Lim, Suhyun Kweon, Donald Tan, Jodhbir S. Mehta
Summary: Cosmetic contact lens related corneal infections in Asia account for a significant proportion of overall cases, predominantly affecting young females who wear hydrogel lenses.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2021)
Article
Ophthalmology
Nicole A. Carnt, Ryan E. K. Man, Eva K. Fenwick, Ecosse L. Lamoureux, Lisa J. Keay
Summary: This study found that AK has a significant and substantial impact on all three domains of VRQOL, regardless of sociodemographic factors. Patients with AK who experienced poor outcomes, British White race (compared to other races) and female, had lower VRQOL scores across all domains. Lower income patients with AK scored worse on Reading and Mobility domains, while those with lower education had poorer Emotional scores.
Article
Ophthalmology
Nicole Carnt, Darwin C. Minassian, John K. G. Dart
Summary: This study aims to identify the risk factors for Acanthamoeba keratitis (AK) in daily disposable (DD) contact lens users compared to daily wear (DW) reusable lens users and specific risks for DD users. It is important because CL use is the main cause of microbial keratitis in many major economies, with AK accounting for approximately 50% of sight loss cases. Determining these AK risks informs practitioner advice and consumer behavior.
Article
Microbiology
Cindy McAnally, Rhonda Walters, Allison Campolo, Valerie Harris, Jamie King, Megan Thomas, Manal M. Gabriel, Paul Shannon, Monica Crary
Summary: This study compared the efficacy of nine major MPSs on the global market against four different microorganism species and four common contact lenses. The majority of MPSs demonstrated significantly higher disinfection efficacies without contact lenses, with OPTI-FREE products showing the highest disinfection efficacy when paired with any contact lens.
Article
Ophthalmology
Marta Vianya-Estopa, Nery Garcia-Porta, David P. Pinero, Luisa Simo Mannion, Eldre W. Beukes, James S. Wolffsohn, Peter M. Allen
Summary: The study found that most contact lens wearers in Spain followed hand hygiene regulations during the COVID-19 pandemic, but there were still areas for improvement such as the 20-second handwashing rule and using shared towels. Factors needing attention included lens case cleaning and renewal, avoiding water exposure, and knowing when to cease lens wear. Continued education by eye care practitioners is essential to ensure safe contact lens wear during the pandemic.
CONTACT LENS & ANTERIOR EYE
(2021)
Article
Ophthalmology
Marta Vianya-Estopa, James S. Wolffsohn, Eldre Beukes, Mike Trott, Lee Smith, Peter M. Allen
Summary: During the COVID-19 pandemic, majority of contact lens wearers followed hygiene recommendations, but some reduced the frequency of lens usage. High compliance was observed in handwashing practices, however, soft reusable lens wearers exhibited lower compliance in lens wear and care compared to daily disposable lens wearers.
CONTACT LENS & ANTERIOR EYE
(2021)
Article
Ophthalmology
Angelica C. Scanzera, Elmer Y. Tu, Charlotte E. Joslin
Summary: The study aimed to explore whether orthokeratology may increase the frequency of Acanthamoeba keratitis compared with other lens modalities. Findings showed that the proportion of orthokeratology cases among AK minors exceeded the expected proportion based on market penetrance, suggesting a potential increased risk of AK in orthokeratology users.
EYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICE
(2021)
Review
Medicine, General & Internal
Philip Maier, Paola Kammrath Betancor, Thomas Reinhard
Summary: Wearing contact lenses, especially soft ones, carries a risk of microbial keratitis if proper hygiene is not maintained. Although this condition rarely causes permanent vision damage, meticulous care is still necessary for contact lens use.
DEUTSCHES ARZTEBLATT INTERNATIONAL
(2022)
Article
Ophthalmology
Memoona Arshad, Nicole Carnt, Jacqueline Tan, Fiona Stapleton
Summary: The study found that placing a no-water sticker on the contact lens case significantly reduced overall water exposure behaviors and storage case endotoxin levels in contact lens wearers. However, there were no significant changes in individual water-contact behaviors or overall storage case contamination.
Article
Oncology
Zeze T. H. Atwa, Wafaa Y. Abdel Wahed
PEDIATRIC BLOOD & CANCER
(2019)
Article
Parasitology
Eman M. H. Meabed, Dalia N. Abdelhafez, Yasser F. Abdelaliem
Article
Neurosciences
Hala A. Shaheen, Wafaa Y. Abdel Wahed, Sharbat T. Hasaneen
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2019)
Article
Biotechnology & Applied Microbiology
Sylvana N. Gaber, Eman Elsayed Mahmoud Hemeda, Hebat-Allah Sayed Elsayeh, Wafaa Y. Abdel Wahed, Mahmoud A. F. Khalil, Enas G. Ibrahim
JOURNAL OF PURE AND APPLIED MICROBIOLOGY
(2020)
Article
Pediatrics
Noha A. Hassuna, Ebtesam Elgezawy, Suzan O. Mousa, Reem A. AbdelAziz, Reham A. Ibrahem, Wafaa Yousif Abdel Wahed, Khalid A. Nasif, Enas M. Hefzy
Summary: The study found that soluble Mannose Receptor, Presepsin, and Monocyte Chemoattractant Protein-1 can be used as markers to differentiate between sepsis and SIRS in critically ill children. In septic cases, soluble Mannose Receptor and Procalcitonin have positive correlations with factors such as disease severity.
Article
Rheumatology
Soha Senara, Hisham Salah, Wafaa Abdel Wahed, Ahmed Yehia
Summary: The aim of this study was to screen for the new development of fibromyalgia syndrome (FMS) and anxiety in rheumatic diseases (RDs) patients and control who recovered from coronavirus disease 2019 (COVID-19). The results showed that FMS and anxiety were significantly higher in cases than control. Severity of COVID-19, diabetes, and anxiety were significant predictors of FMS development.
EGYPTIAN RHEUMATOLOGIST
(2023)
Article
Psychiatry
Hala A. Shaheen, Assem F. Elessawy, Wafaa Abdel-Wahed, Asmaa N. Mohamed, Radwa A. Elhefny
Summary: Depression is common and neurocognitive dysfunction is a significant complication of idiopathic pulmonary fibrosis (IPF). Patients with IPF often experience depressive symptoms, with a significant association between depression and hypoxia. Cognitive examination results showed significant differences in MMSE between IPF patients and healthy controls, and MMSE and TMTB scores were significantly associated with pulmonary arterial hypertension.
MINERVA PSYCHIATRY
(2021)
Article
Rheumatology
Hanan M. Fathi, Wafaa Y. Abdel Wahed, Ahmad A. Gomaa, Essam A. Hassan, Hanaa M. Eid, Fadwa Abdel Reheem, Soha H. Senara
EGYPTIAN RHEUMATOLOGY AND REHABILITATION
(2020)
Article
Public, Environmental & Occupational Health
Wafaa Y. Abdel Wahed, Eman Ahmed, Safaa K. Hassan, Enas G. Ibrahim, Hanaa M. Eid
JOURNAL OF PUBLIC HEALTH-HEIDELBERG
(2020)
Article
Health Policy & Services
Wafaa Yousif Abdel Wahed, Enas Mamdouh Hefzy, Mona Ibrahim Ahmed, Nashwa Sayed Hamed
JOURNAL OF COMMUNITY HEALTH
(2020)
Article
Public, Environmental & Occupational Health
Naglaa A. El-Sherbiny, Eman H. Ibrahim, Wafaa Y. Abdel-Wahed
JOURNAL OF THE EGYPTIAN PUBLIC HEALTH ASSOCIATION
(2020)
Article
Public, Environmental & Occupational Health
Enas G. Ibrahim, Wafaa Y. Abdel Wahed, Hanaa M. Eid, Wessam S. Deeb
JOURNAL OF THE EGYPTIAN PUBLIC HEALTH ASSOCIATION
(2019)
Meeting Abstract
Respiratory System
Radwa Elhefny, Assem Elessawy, Hala Shaheen, Asmaa Mohamed
EUROPEAN RESPIRATORY JOURNAL
(2018)
Meeting Abstract
Rheumatology
S. H. Senara, W. Y. Abdel Wahed, S. E. Mabrouk
ANNALS OF THE RHEUMATIC DISEASES
(2018)
Article
Pharmacology & Pharmacy
Eman I. Ahmed, Wafaa Y. Abdel Wahed, Essam A. Hassan, Tarek I. Ahmed
CURRENT DRUG SAFETY
(2018)
Article
Public, Environmental & Occupational Health
Rodrigo C. Menezes, Isabella B. B. Ferreira, Luciana Sobral, Stefania L. Garcia, Hugo N. Pustilnik, Mariana Araujo-Pereira, Bruno B. Andrade
Summary: This study aimed to identify the clinical features associated with viral pathogens responsible for severe lower respiratory tract infections (LRTI) in children. The study found that different viral agents have distinct associations with clinical features in children.
JOURNAL OF INFECTION AND PUBLIC HEALTH
(2024)
Article
Public, Environmental & Occupational Health
Ambrina Khatoon, Syed F. Hussain, Syed M. Shahid, Santosh Kumar Sidhwani, Salman Ahmed Khan, Omer Ahmed Shaikh, Abdulqadir J. Nashwan
Summary: Despite the increasing incidence of Staphylococcus aureus infection and dissemination in Pakistan, research on the epidemiology of different Staphylococcus aureus clones has been limited. This study used multilocus sequence typing (MLST) to analyze the epidemiology of Staphylococcus aureus in the area, finding high diversity of locally circulating clones defined by their geographic epidemiology.
JOURNAL OF INFECTION AND PUBLIC HEALTH
(2024)
Review
Public, Environmental & Occupational Health
Amir Khorram-Manesh, Krzysztof Goniewicz, Frederick M. Burkle Jr
Summary: This article discusses the management approach for globalized diseases in a globalized world. Through literature review and analysis, key focuses including data-driven decision-making, robust technology infrastructure, global cooperation, and ongoing public health education are identified. The weaknesses of current pandemic management systems are revealed, and recommendations for strengthening future pandemic management are provided.
JOURNAL OF INFECTION AND PUBLIC HEALTH
(2024)
Article
Public, Environmental & Occupational Health
Mst S. Munira, Yuta Okada, Hiroshi Nishiura
Summary: This study estimates the life expectancy at birth in Japan at the end of 2022 using death datasets from Aichi and Fukui prefectures. The results suggest that the impact of the pandemic on life expectancy was relatively small by the end of 2022.
JOURNAL OF INFECTION AND PUBLIC HEALTH
(2024)