Article
Public, Environmental & Occupational Health
Mursal A. Mohamud, David J. T. Campbell, James Wick, Alexander A. Leung, Gabriel E. Fabreau, Marcello Tonelli, Paul E. Ronksley
Summary: This study aimed to describe the trends in multimorbidity and the differential contribution of individual chronic conditions to multimorbidity among hospitalized populations in the United States. The study found that there was an increase in multimorbidity among all racial/ethnic groups from 1993 to 2012, with the largest increases seen in White, Black, and Native American populations. Additionally, metabolic diseases, particularly diabetes and obesity, had an increasing contribution to multimorbidity, especially among Hispanic patients.
INTERNATIONAL JOURNAL FOR EQUITY IN HEALTH
(2023)
Article
Multidisciplinary Sciences
Anshul Saxena, Venkataraghavan Ramamoorthy, Muni Rubens, Peter McGranaghan, Emir Veledar, Khurram Nasir
Summary: During the past decade, various reforms have been implemented in the US to improve primary care. This study used national data to assess the quality of primary care and found a decrease in preventable hospitalizations, except for diabetes short-term complications and lower-extremity amputations, which showed an increase in hospitalizations.
SCIENTIFIC REPORTS
(2022)
Article
Medicine, General & Internal
Muni Rubens, Venkataraghavan Ramamoorthy, Anshul Saxena, Peter McGranaghan, Elise McCormack-Granja
Summary: This study examined trends in diabetes-related hospitalizations from 2010 to 2019 and found that the overall population-adjusted diabetes hospitalizations significantly increased during this time period. The analysis also revealed that hospitalizations increased for a certain age group and for males within a specific age group. Furthermore, the total hospitalization charge for diabetes-related cases also showed a notable increase. These findings highlight the importance of screening, preventing, and managing diabetes at a younger age.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Microbiology
Kaitlin Benedict, Ian Hennessee, Jeremy A. W. Gold, Dallas J. Smith, Samantha Williams, Mitsuru Toda
Summary: This study analyzed blastomycosis-associated hospitalizations in the United States from 2010 to 2020. The results showed a relatively low hospitalization rate with no apparent temporal trend, but higher rates among individuals aged 65 and older and males. The in-hospital death rate increased during this period and was associated with age, chronic obstructive pulmonary disease, and malignancy.
Article
Clinical Neurology
Quanhe Yang, Xin Tong, Sallyann Coleman King, Benjamin S. Olivari, Robert K. Merritt
Summary: Hospitalizations for stroke among Medicare fee-for-service beneficiaries aged >= 65 significantly decreased during the initial weeks of the COVID-19 pandemic (March 1-June 6) with a reduction of 22.3%-12.1%. Reductions were similar across different age, sex, and race/ethnicity groups. Variability in stroke hospitalization reductions was observed among different states.
Article
Public, Environmental & Occupational Health
Maeve E. Wallace
Summary: The rate of pregnancy-associated homicides in 2020 increased significantly, particularly among adolescents and non-Hispanic Black women. Most incidents involved firearms. Pregnant and postpartum women had a 35% higher risk of homicide compared to their nonpregnant counterparts.
AMERICAN JOURNAL OF PUBLIC HEALTH
(2022)
Article
Immunology
Eileen Lee, Benjamin Bates, Nathaniel Kuhrt, Kathleen M. Andersen, Aayush Visaria, Rachel Patel, Soko Setoguchi
Summary: This study examined the utilization patterns of anticoagulation (AC) among hospitalized COVID-19 patients and found that 64% received AC and 24% received therapeutic AC. The use of therapeutic AC decreased over time, especially after December 2021. Factors associated with therapeutic AC included age, sex, race, obesity, length of stay, and invasive ventilation.
JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Environmental Sciences
Kate R. Weinberger, Xiao Wu, Shengzhi Sun, Keith R. Spangler, Amruta Nori-Sarma, Joel Schwartz, Weeberb Requia, Benjamin M. Sabath, Danielle Braun, Antonella Zanobetti, Francesca Dominici, Gregory A. Wellenius
Summary: Heat alerts were not found to be associated with lower mortality, but were linked to higher rates of hospitalization due to fluid and electrolyte disorders and heat stroke, potentially indicating that heat alerts prompt individuals to seek medical care.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Allergy
Anna Chen Arroyo, Lacey B. Robinson, Rebecca E. Cash, Mohammad Kamal Faridi, Kohei Hasegawa, Carlos A. Camargo
Summary: The study reveals an increasing trend in emergency department visits and hospitalizations for anaphylaxis among older adults in the United States. Drug-related triggers contribute significantly to this rise, posing a growing risk in this vulnerable population. Older age and drug-related triggers are identified as risk factors for anaphylaxis-related death.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2021)
Article
Medicine, General & Internal
Orly Termeie, Lawrence Fiedler, Lisa Martinez, Jennifer Foster, Parvathi Perumareddi, Robert S. Levine, Charles H. Hennekens
Summary: This study compared the trends in mortality from alcoholic cirrhosis in the United States between 1999 and 2019 using data from the CDC. The results showed a significant increase in the mortality rate of alcoholic cirrhosis, which may be attributed to heavy alcohol consumption and the obesity epidemic. Further research and intervention are needed to address these alarming trends.
AMERICAN JOURNAL OF MEDICINE
(2022)
Article
Obstetrics & Gynecology
Chelsea N. Fortin, Charley Jiang, Martina T. Caldwell, Sawsan As-Sanie, Vanessa Dalton, Erica E. Marsh
Summary: The study found that emergency department visits for leiomyomas are increasing while admission rates are decreasing. Factors associated with admission include age, presenting complaints, income level, and type of insurance.
OBSTETRICS AND GYNECOLOGY
(2021)
Article
Microbiology
Patrick Saunders-Hastings, Cindy Ke Zhou, Shayan Hobbi, Eva Boyd, Patricia Lloyd, Nader Alawar, Timothy Burrell, Jeff Beers, Tainya C. C. Clarke, Aaron Z. Z. Hettinger, Hui-Lee Wong, Azadeh Shoaibi
Summary: This study provides an overview of the demographics, clinical characteristics, treatments, and outcomes of hospitalized COVID-19 patients in the U.S. during the pre-vaccine phase. The majority of patients were over 30 years old and had comorbidities such as cardiovascular/respiratory diseases and diabetes. Anticoagulants were commonly used, and the administration of remdesivir increased over time. Patients showed higher disease severity after 14 days of admission compared to before admission. The median length of hospital stay was 4-6 days, and most patients were discharged alive.
Article
Critical Care Medicine
Shehabaldin Alqalyoobi, Shu-Yi Liao, Waqas Qureshi, Ogugua Ndili Obi
Summary: Hospitalization rates for patients with pulmonary sarcoidosis and respiratory failure are increasing in the United States, but inpatient mortality rates caused by respiratory failure have declined. Older age, respiratory failure, pulmonary hypertension, and frailty are important predictors of inpatient mortality in hospitalized patients with pulmonary sarcoidosis.
Article
Public, Environmental & Occupational Health
Megan Swanson, Amy Pickrel, John Williamson, Susan Montgomery
Summary: This report reveals a significant increase in babesiosis incidence in the northeastern states of the United States from 2011 to 2019. In addition to the known endemic areas, three states (Maine, New Hampshire, and Vermont) that were not considered to have endemic transmission also experienced a significant increase in incidence, with case counts similar to or higher than the seven known endemic states. Public health practice should focus on strengthening tick prevention messaging, provider education, and traveler risk awareness.
MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT
(2023)
Article
Medicine, General & Internal
Po-Hung Chen, Lauren Johnson, Berkeley N. Limketkai, Emily Jusuf, Jing Sun, Brian Kim, Jennifer C. Price, Tinsay A. Woreta
Summary: This study aimed to estimate the temporal trend of HCV-positive pregnancies during the opioid epidemic and identify HCV-associated maternal and perinatal outcomes. The study found that the prevalence of HCV-positive pregnancies increased significantly and was associated with increased risks for adverse perinatal outcomes.
Review
Emergency Medicine
Lucas Oliveira J. e Silva, Steven D. Prakken, Andrew C. Meltzer, Joshua S. Broder, Danielle J. Gerberi, Suneel Upadhye, Christopher R. Carpenter, Fernanda Bellolio
Summary: There is currently no evidence confirming that screening for depression or anxiety in emergency department patients with recurrent and undifferentiated abdominal pain improves outcomes or changes management downstream.
ACADEMIC EMERGENCY MEDICINE
(2022)
Review
Emergency Medicine
Christopher R. Carpenter, Richard T. Griffey, Angela Mills, Michelle Doering, Lucas Oliveira J. e Silva, Fernanda Bellolio, Suneel Upadhye, Joshua S. Broder
Summary: Despite the lack of direct evidence, a scoping review found insufficient evidence to determine whether repeat CT imaging is necessary for low-risk recurrent abdominal pain patients. The studies analyzed did not provide clear guidelines on when and if repeat CT scans should be performed in this patient population.
ACADEMIC EMERGENCY MEDICINE
(2022)
Article
Emergency Medicine
Lucas Oliveira J. e Silva, Jessica A. Stanich, Molly M. Jeffery, Aidan F. Mullan, Susan M. Bower, Ronna L. Campbell, Alejandro A. Rabinstein, Robert J. Pignolo, Fernanda Bellolio
Summary: The study derived a risk score that can identify high-risk geriatric patients for delirium screening using variables available early in the emergency department encounter. The risk score includes variables from triage information and early history taking, and shows high sensitivity and specificity in detecting delirium in older adults. Validation of the REDEEM score is necessary before implementation for assisting delirium-targeted screening in high-risk geriatric patients in the ED.
ACADEMIC EMERGENCY MEDICINE
(2022)
Editorial Material
Emergency Medicine
Christopher R. Carpenter, Lucas Oliveira J. Silva, Suneel Upadhye, Joshua S. Broder, Fernanda Bellolio
ACADEMIC EMERGENCY MEDICINE
(2022)
Article
Emergency Medicine
Joshua S. Broder, Lucas Oliveira J. e Silva, Fernanda Bellolio, Caroline E. Freiermuth, Richard T. Griffey, Edmond Hooker, Timothy B. Jang, Andrew C. Meltzer, Angela M. Mills, Joan D. Pepper, Steven D. Prakken, Michael D. Repplinger, Suneel Upadhye, Christopher R. Carpenter
Summary: This guideline provides recommendations for the management of low-risk, recurrent abdominal pain in emergency department patients, highlighting the need for future research in this area.
ACADEMIC EMERGENCY MEDICINE
(2022)
Letter
Emergency Medicine
Alexa L. Thomas, Adrian Beyde, Benjamin J. Sandefur, Kristina M. Colbenson, Imtithal Kisirwan, Anissa L. Finley, Aidan F. Mullan, Aaron J. Krych, Ronna L. Campbell
ACADEMIC EMERGENCY MEDICINE
(2022)
Review
Emergency Medicine
Vishal Paresh Shah, Lucas Oliveira J. e Silva, Wigdan Farah, Mohamad Seisa, Abdalla Kara Balla, April Christensen, Magdoleen Farah, Bashar Hasan, Fernanda Bellolio, M. Hassan Murad
Summary: This study evaluated the diagnostic test accuracy of neuroimaging for patients presenting with acute vertigo or dizziness. The results showed that noncontrast CT has very low sensitivity and MRI will miss approximately one in five patients with stroke if imaging is obtained early after symptom onset. Therefore, the evidence does not support neuroimaging as the only tool for ruling out stroke and other central causes in patients with acute dizziness or vertigo presenting to the emergency department.
ACADEMIC EMERGENCY MEDICINE
(2023)
Letter
Emergency Medicine
Fernanda Bellolio, Joshua S. Broder, Lucas Silva, Caroline E. Freiermuth, Edmond Hooker, Timothy B. Jang, Richard T. Griffey, Andrew C. Meltzer, Angela M. Mills, Joan Pepper, Steven Prakken, Michael D. Repplinger, Suneel Upadhye, Christopher R. Carpenter
ACADEMIC EMERGENCY MEDICINE
(2022)
Review
Emergency Medicine
Lucas Oliveira J. e Silva, Danya Khoujah, James G. Naples, Jonathan A. Edlow, Danielle J. Gerberi, Christopher R. Carpenter, Fernanda Bellolio
Summary: This umbrella review summarizes the evidence of corticosteroids use for the treatment of vestibular neuritis (VN). The findings suggest that corticosteroids may improve complete caloric recovery in patients with VN, but the impact on clinical improvement is uncertain. Corticosteroids may also lead to minor adverse effects. Therefore, the evidence for the use of corticosteroids in the emergency department for the treatment of VN is limited.
ACADEMIC EMERGENCY MEDICINE
(2023)
Letter
Emergency Medicine
Summer Ghaith, Sandeep S. Voleti, Fernanda Bellolio, Jonathan A. Edlow, Rachel A. Lindor
ACADEMIC EMERGENCY MEDICINE
(2023)
Review
Emergency Medicine
Vishal Paresh Shah, Lucas Oliveira J e Silva, Wigdan Farah, Mohamed O. Seisa, Abdalla Kara Balla, April Christensen, Magdoleen Farah, Bashar Hasan, Fernanda Bellolio, M. Hassan Murad
Summary: History and physical examination are important for diagnosing central versus peripheral causes of acute vertigo. A systematic review and meta-analysis found that most neurological examination findings have low sensitivity but high specificity for a central cause. However, in acute vestibular syndrome, HINTS and HINTS+ performed by trained clinicians have high sensitivity.
ACADEMIC EMERGENCY MEDICINE
(2023)
Review
Emergency Medicine
Danya Khoujah, James G. Naples, Lucas Oliveira J. e Silva, Jonathan A. Edlow, Danielle J. Gerberi, Christopher R. Carpenter, Fernanda Bellolio
Summary: The Epley maneuver is effective in treating posterior canal benign paroxysmal positional vertigo (BPPV), leading to higher resolution of vertigo and conversion to negative Dix-Hallpike test. Further studies are needed to investigate its implementation and education of clinicians in the emergency department.
ACADEMIC EMERGENCY MEDICINE
(2023)
Article
Clinical Neurology
Yuedan Zhang, Jonathan H. Smith, Aidan F. Mullan, Derek E. Vanmeter, Joel R. Anderson, Ronna L. Campbell
Summary: This study investigated the frequency of headache and its association with other factors in patients with anaphylaxis. The results showed that 27% of patients with anaphylaxis reported headache symptoms. Female patients had a higher likelihood of experiencing headache compared to male patients, and dyspnea was associated with the presence of headache. This study suggests that headache may serve as a marker for neurological involvement in anaphylaxis.
Letter
Emergency Medicine
David Newman-Toker, Fernanda Bellolio
ACADEMIC EMERGENCY MEDICINE
(2023)