Systemic Acrolein Elevations in Mice With Experimental Autoimmune Encephalomyelitis and Patients With Multiple Sclerosis

Dimercaprol is an acrolein scavenger that mitigates acrolein-mediated PC-12 cells toxicity and reduces acrolein in rat following spinal cord injury

(2017) Ran Tian et al.   JOURNAL OF NEUROCHEMISTRY

Elevated axonal membrane permeability and its correlation with motor deficits in an animal model of multiple sclerosis

(2017) Gary Leung et al.   Translational Neurodegeneration

Mitigation of sensory and motor deficits by acrolein scavenger phenelzine in a rat model of spinal cord contusive injury

(2016) Zhe Chen et al.   JOURNAL OF NEUROCHEMISTRY

Molecular mechanisms of acrolein-mediated myelin destruction in CNS trauma and disease

(2015) R. Shi et al.   FREE RADICAL RESEARCH

Acrolein detection: potential theranostic utility in multiple sclerosis and spinal cord injury

(2014) Melissa Tully et al.   Expert Review of Neurotherapeutics

Acrolein as a novel therapeutic target for motor and sensory deficits in spinal cord injury

(2014) Riyi Shi et al.   Neural Regeneration Research

Acute systemic accumulation of acrolein in mice by inhalation at a concentration similar to that in cigarette smoke

(2014) Melissa Tully et al.   Neuroscience Bulletin

New Insights in the Pathogenesis of Multiple Sclerosis—Role of Acrolein in Neuronal and Myelin Damage

(2013) Melissa Tully et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Development and Validation of a Direct LC-MS-MS Method to Determine the Acrolein Metabolite 3-HPMA in Urine

(2013) W. Yan et al.   JOURNAL OF CHROMATOGRAPHIC SCIENCE

Acrolein involvement in sensory and behavioral hypersensitivity following spinal cord injury in the rat

(2013) Michael R. Due et al.   JOURNAL OF NEUROCHEMISTRY

Neuroprotective role of hydralazine in rat spinal cord injury-attenuation of acrolein-mediated damage

(2013) Jonghyuck Park et al.   JOURNAL OF NEUROCHEMISTRY

Determination of Urine 3-HPMA, a Stable Acrolein Metabolite in a Rat Model of Spinal Cord Injury

(2013) Lingxing Zheng et al.   JOURNAL OF NEUROTRAUMA

Acrolein induces myelin damage in mammalian spinal cord

(2011) Yunzhou Shi et al.   JOURNAL OF NEUROCHEMISTRY

Acrolein-mediated injury in nervous system trauma and diseases

(2011) Riyi Shi et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Anti-acrolein treatment improves behavioral outcome and alleviates myelin damage in experimental autoimmune enchephalomyelitis mouse

(2010) G. Leung et al.   NEUROSCIENCE

Determination of six hydroxyalkyl mercapturic acids in human urine using hydrophilic interaction liquid chromatography with tandem mass spectrometry (HILIC–ESI-MS/MS)

(2009) Elisabeth Eckert et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Acrolein scavenging: a potential novel mechanism of attenuating oxidative stress following spinal cord injury

(2009) Kristin Hamann et al.   JOURNAL OF NEUROCHEMISTRY

Carbonyl scavenger and antiatherogenic effects of hydrazine derivatives

(2008) Sylvain Galvani et al.   FREE RADICAL BIOLOGY AND MEDICINE

Critical role of acrolein in secondary injury followingex vivospinal cord trauma

(2008) Kristin Hamann et al.   JOURNAL OF NEUROCHEMISTRY

Multiple sclerosis

(2008) Alastair Compston et al.   LANCET

Neuropathic pain behaviours in a chronic-relapsing model of experimental autoimmune encephalomyelitis (EAE)

(2008) Camille J. Olechowski et al.   PAIN

Simultaneous determination of mercapturic acids derived from ethylene oxide (HEMA), propylene oxide (2-HPMA), acrolein (3-HPMA), acrylamide (AAMA) andN,N-dimethylformamide (AMCC) in human urine using liquid chromatography/tandem mass spectrometry

(2008) Thomas Schettgen et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY