Article
Veterinary Sciences
Kazuyuki Yoshikawa, Takio Kitazawa, Tadashi Sano, Takumi Ino, Tomoya Miyasaka
Summary: Sit-to-stand and stand-to-sit motions are commonly used as therapeutic exercises for dogs with functional impairments. This study characterized the kinematic characteristics of these motions in dogs and compared them with walking. The results showed that the sit-to-stand motion differed from walking, but it was not possible to classify the motions into multiple phases based solely on the transition of hindlimb range of motion.
RESEARCH IN VETERINARY SCIENCE
(2023)
Article
Engineering, Biomedical
Yang-An Li, Ze-Jian Chen, Chang He, Xiu-Pan Wei, Nan Xia, Ming-Hui Gu, Cai-Hua Xiong, Qin Zhang, Trisha M. Kesar, Xiao-Lin Huang, Jiang Xu
Summary: Abnormal muscle synergies during sit-to-stand (STS) transitions have been observed post-stroke. Exoskeleton-assisted STS training intervention can partially restore normal muscle synergies and improve clinical scores in stroke survivors.
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING
(2023)
Article
Robotics
Hiroki Kogami, Qi An, Ningjia Yang, Ruoxi Wang, Kazunori Yoshida, Hiroyuki Hamada, Hiroshi Yamakawa, Yusuke Tamura, Shingo Shimoda, Hiroshi Yamasaki, Moeka Yokoyama, Fady Alnajjar, Noriaki Hattori, Koji Takahashi, Takanori Fujii, Hironori Otomune, Ichiro Miyai, Atsushi Yamashita, Hajime Asama
Summary: This study examined the sit-to-stand motions of 21 hemiplegic patients within three months of stroke onset. It was found that severe patients in the subacute period exhibited biased standing on the non-paralyzed side, with muscle synergy activation timing for whole-body extension occurring earlier than in mild patients.
Article
Rehabilitation
Juliane Franco, Paula Fernanda de Sousa Silva, Alice Rausch Menezes, Sherindan Ayessa Ferreira de Brito, Christina Danielli Coelho de Morais Faria
Summary: The purpose of this study was to compare the trunk biomechanical characteristics during sit-to-stand and stand-to-sit tasks in stroke survivors and healthy-matched controls. The results showed that stroke survivors had a greater range of trunk forward flexion and longer duration for both tasks.
DISABILITY AND REHABILITATION
(2023)
Article
Robotics
Tatiana D. Luna, Victor Santamaria, Xupeng Ai, Sunil K. Agrawal
Summary: This study aims to understand how healthy adults react to physical perturbations when transitioning from sitting to standing. The results show that the direction of perturbations had the most distinguishable change among participants, and as the perturbation intensities increased, participants required an increase in trunk movement to maintain balance. These findings provide important insights for designing future sit-to-stand perturbation-based training programs for individuals prone to falling.
IEEE ROBOTICS AND AUTOMATION LETTERS
(2022)
Article
Psychology, Multidisciplinary
Prithvi Kantan, Erika G. Spaich, Sofia Dahl
Summary: Interactive sonification of biomechanical quantities is gaining relevance in movement rehabilitation and monitoring. This study proposes a general sonification model for the sit-to-stand (STS) transfer, incorporating both fixed and flexible components to represent the rising motion and clinical features of STS. The model was evaluated with a listening test experiment, showing that participants were able to accurately classify different STS patterns and that the amount of sonified kinematic information significantly impacted accuracy.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Neurosciences
Ruoxi Wang, Qi An, Ningjia Yang, Hiroki Kogami, Kazunori Yoshida, Hiroshi Yamakawa, Hiroyuki Hamada, Shingo Shimoda, Hiroshi R. Yamasaki, Moeka Yokoyama, Fady Alnajjar, Noriaki Hattori, Kouji Takahashi, Takanori Fujii, Hironori Otomune, Ichiro Miyai, Atsushi Yamashita, Hajime Asama
Summary: In this study, a novel joint torque-based normalization method was proposed to quantify changes in muscle tension and muscle synergy activation levels in post-stroke patients during sit-to-stand rehabilitation. The method was validated against healthy participants and showed significant differences in muscle activation amplitude for inter- and intra-subject comparisons. The proposed method also demonstrated higher simulation accuracy compared to the common static optimization method.
FRONTIERS IN SYSTEMS NEUROSCIENCE
(2022)
Article
Rehabilitation
Natsuki Shimizu, Hiroyuki Hashidate, Tomohiro Ota, Yumi Kawai
Summary: This study investigated the impact of sit-to-stand, standing, and stand-to-sit abilities on physical activity in subacute stroke patients and found that those who could perform these activities had higher levels of light-intensity physical activity. This suggests that improving these abilities could increase the opportunity for engaging in light-intensity physical activity.
PHYSIOTHERAPY THEORY AND PRACTICE
(2023)
Article
Chemistry, Analytical
Thomas Bennett, Praveen Kumar, Virginia Ruiz Garate
Summary: This study presents the recording and analysis of sit-to-stand-to-sit movements in stroke and non-stroke subjects, using machine learning to predict vertical motion trajectories for robot control. The predicted trajectories matched the true ones for non-stroke subjects, showing potential for further research and applications in assistive robotics.
Article
Biophysics
Eline van Der Kruk, Anne K. Silverman, Peter Reilly, Anthony M. J. Bull
Summary: The decline in capacity with age may result in limitations in the ability to stand up. Compensation is key in understanding this decline, but is underexplored in current literature. Future studies should focus on varying arm push-off strategies, sit-to-walk, biomechanical implications of asymmetry, and assessments of physical capacity and psychological priorities.
JOURNAL OF BIOMECHANICS
(2021)
Article
Chemistry, Analytical
Andres Aguirre, Maria J. Pinto, Carlos A. Cifuentes, Oscar Perdomo, Camilo A. R. Diaz, Marcela Munera
Summary: High-intensity exercises have better results in general health conditions, but monitoring patients' conditions is essential to avoid extreme fatigue. A computational model is proposed to estimate fatigue during sit-to-stand exercises.
Article
Medicine, General & Internal
Jin Li, Qiang Xue, Shuo Yang, Xiaolong Han, Shouwei Zhang, Min Li, Jingchen Guo
Summary: This study investigated the law of sit-to-stand (STS) motion in healthy adults through experiments, analyzing the relationship between human body parameters and motion parameters and providing recommendations for the design of STS assistive devices based on different phases of STS motion.
Article
Engineering, Electrical & Electronic
Kenshi Saho, Keitaro Shioiri, Keisuke Inuzuka
Summary: This study combines micro-Doppler radar data from different movements to achieve high accuracy in identifying 10 individuals using a convolutional neural network, outperforming traditional methods. Despite the relatively small training set, the method shows promising accuracy in identifying participants with similar ages and physical features.
IEEE SENSORS JOURNAL
(2021)
Article
Multidisciplinary Sciences
Michael Herzog, Frieder C. Krafft, Bernd J. Stetter, Andrea d'Avella, Lizeth H. Sloot, Thorsten Stein
Summary: This study investigated the effects of rollator support on sit-to-stand and stand-to-sit movements and found that individuals adjust their movement strategies based on different conditions. The findings can be applied to older individuals to recommend safe strategies and reduce the risk of falls.
SCIENTIFIC REPORTS
(2023)
Article
Clinical Neurology
Matthew A. A. Edwardson, Kathaleen Brady, Margot L. L. Giannetti, Shashwati Geed, Jessica Barth, Abigail Mitchell, Ming T. T. Tan, Yizhao Zhou, Barbara S. S. Bregman, Elissa L. L. Newport, Dorothy F. F. Edwards, Alexander W. W. Dromerick
Summary: The Critical Periods After Stroke Study (CPASS) found that additional intensive upper limb therapy of 20 hours led to variable gains on the Action Research Arm Test depending on the time therapy started post-stroke. The subacute group improved significantly, the acute group showed smaller but statistically significant improvement, while the chronic group did not show significant improvement. The study argues for a large dose of motor therapy continuously delivered in the acute and subacute phases, rather than shifting therapy to outpatient care 2 to 3 months post-stroke.
NEUROREHABILITATION AND NEURAL REPAIR
(2023)
Article
Neurosciences
Xinyi Zheng, Jie Luo, Lingyun Deng, Bing Li, Le Li, Dong Feng Huang, Rong Song
Summary: This study utilized fNIRS to investigate the functional connectivity between different brain regions during grip force tracking tasks. The results revealed that the FC was stronger in interhemispheric homologous pairs, with the FC between IPFC and rPFC being enhanced during high task load, while the FC within intrahemispheric region pairs also increased with higher task load.
JOURNAL OF NEUROSCIENCE RESEARCH
(2021)
Article
Neurosciences
Yan Leng, Wai Leung Ambrose Lo, Chengpeng Hu, Ruihao Bian, Zhiqin Xu, Xiyao Shan, Dongfeng Huang, Le Li
Summary: The study demonstrated the influence of both neural and peripheral factors on post-stroke wrist joint spasticity. Radial extracorporeal shock wave (rESW) intervention may be more effective in addressing non-neural components of spasticity. Clinical management should take into account both neural and non-neural factors for optimal intervention strategies.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Engineering, Biomedical
Yu Zhuang, Yan Leng, Jie Zhou, Rong Song, Le Li, Steven W. Su
Summary: The EMG-based admittance control scheme (EACS) improves movement stability and ankle range of motion for stroke survivors. EACS shows lower assistance torque, tracking error, and jerk values compared to the EMG-based open-loop control scheme (EOCS) in both healthy participants and stroke survivors.
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
(2021)
Article
Neurosciences
Xin Li, Howe Liu, Le Ge, Yifeng Yan, Wai Leung Ambrose Lo, Le Li, Chuhuai Wang
Summary: The study used TMS to investigate changes in the representation of TVA and MF muscles in the cortical network of individuals with cLBP. It found that in cLBP individuals, the MF CoG locations were posterior and lateral, and there was asymmetry between the locations of TVA and MF CoG in the left hemisphere. These findings support the neural basis and clinical treatment of cLBP.
Article
Biophysics
Xiyao Shan, Shun Otsuka, Le Li, Yasuo Kawakami
Summary: This study identified the characteristics of triceps surae muscles and aponeuroses stiffness during graded isometric submaximal plantarflexion efforts in healthy male subjects. The results showed that the muscles and aponeuroses exhibited heterogeneous and anisotropic mechanical properties during muscle contractions. The stiffening effect of muscle belly may influence the mechanical properties of aponeuroses, especially for the lateral gastrocnemius.
JOURNAL OF BIOMECHANICS
(2021)
Article
Computer Science, Artificial Intelligence
Qinghua Huang, Hao Luo, Cui Yang, Jianyi Li, Qifeng Deng, Peng Liu, Maoqing Fu, Le Li, Xuelong Li
Summary: Scoliosis is a disease caused by deformity of the spine. This study developed a novel technique to generate the 3D structure of the human spine using tracked freehand ultrasound scanning. The technique accurately models each vertebra and allows for quantitative monitoring of disease progression through measuring the Cobb angle.
Article
Health Care Sciences & Services
Yan Leng, Wai Leung Ambrose Lo, Yu Rong Mao, Ruihao Bian, Jiang Li Zhao, Zhiqin Xu, Le Li, Dong Feng Huang
Summary: This study explored the impact of cognitive function on functional outcomes in subacute stroke patients after VR intervention. The results showed that VR intervention was effective in improving upper limb function and independence in performing activities of daily living, regardless of cognitive function level. Stroke patients with impaired cognitive function may experience greater improvements in upper limb function and independency after VR intervention.
JMIR SERIOUS GAMES
(2022)
Review
Neurosciences
Xiaohan Wang, Le Ge, Huijing Hu, Li Yan, Le Li
Summary: In recent years, the potential of non-invasive brain stimulation (NIBS) for the therapeutic effect of post-stroke spasticity has been explored. This study evaluated the efficacy of NIBS on spasticity in patients after stroke through a systematic review and meta-analysis. The results showed that repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) had significant impacts on improving spasticity.
Article
Biotechnology & Applied Microbiology
Le Li, Huijing Hu, Bo Yao, Chengjun Huang, Zhiyuan Lu, Cliff S. Klein, Ping Zhou
Summary: This study used surface electromyography (EMG) analysis to examine the neural and muscle changes after spinal cord injury (SCI). The results showed that the muscle fiber conduction velocity (MFCV) was significantly slower in the SCI group compared to the control group, and this difference was observed at all force levels. The EMG-force relation in the SCI group was best fit with negative quadratic coefficients, suggesting impaired EMG modulation at high forces. These findings indicate complex neuromuscular changes after SCI, including alterations in central neural drive and muscle properties.
BIOENGINEERING-BASEL
(2023)
Article
Engineering, Biomedical
Renyu Yang, Zhihang Shen, Yueling Lyu, Yu Zhuang, Le Li, Rong Song
Summary: This study proposed a voluntary assist-as-needed (VAAN) controller for an ankle rehabilitation robot, considering both movement performance and active participation of patients. The controller can switch among four working modes based on the trajectory tracking error, and estimates the voluntary torque of the ankle joint using an EMG-driven musculoskeletal model. Experiment results showed that the proposed VAAN controller achieved higher human contribution ratio than previous studies.
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING
(2023)
Review
Biochemistry & Molecular Biology
Xin Meng, Jiale Wang, Le Li
Summary: This article summarizes various modifications recently implemented in the fast charging of layered oxide cathode materials, including component improvement, morphology control, ion doping, surface coating, and composite structure. The development direction of layered-oxide cathodes is summarized based on research progress. Possible strategies and future development directions of layered-oxide cathodes to improve fast-charging performance are proposed.
Review
Biochemistry & Molecular Biology
Xin Meng, Ziyi Cheng, Le Li
Summary: This paper introduces the zinc storage mechanism of ZMO and reviews the progress in improving the interlayer spacing, structural stability, and diffusivity of ZMO. Various methods such as introducing different intercalated ions, introducing defects, and designing different morphologies are discussed. The development status and future research directions of characterization and analysis techniques for ZMO-based ZIBs are summarized.
Article
Biology
Guang-Quan Zhou, Hao Wei, Xiaoyi Wang, Kai-Ni Wang, Yuzhao Chen, Fei Xiong, Guanqing Ren, Chunying Liu, Le Li, Qinghua Huang
Summary: In this work, we propose an end-to-end boundary-salience multi-branch network, BSMNet, to identify the carotid intima-media from ultrasound images. Our method exploits prior shape knowledge and anatomical dependence to improve the accuracy of boundary identification and incorporates a strip attention model for segmenting thin strip regions. Experimental results demonstrate the promising performance of our method, achieving about 0.02 improvement in Dice and HD95 compared to other state-of-the-art methods. Our method is expected to advance the analysis of systemic arterial disease with ultrasound imaging.
COMPUTERS IN BIOLOGY AND MEDICINE
(2023)
Article
Engineering, Electrical & Electronic
Jiahui Xu, Ye Fan, Minghao Wang, Bowen Ji, Le Li, Minyi Jin, Siyan Shang, Chuner Ni, Yuhua Cheng, Linxi Dong, Gaofeng Wang
Summary: High-quality recording of human bio-signals is crucial for biomedical engineering research and clinical medical diagnosis. This study introduces a highly reliable and reusable microneedle array electrode (MAE) technology, which overcomes the issues associated with traditional wet electrodes. The MAE, modified with silver nanoparticles and poly(3,4-ethylenedioxythiophene):poly(sodiumstyrenesulfonate), exhibits significantly improved impedance and signal-to-noise ratio, providing a promising alternative for stable bio-signal recording on the skin.
IEEE SENSORS JOURNAL
(2023)
Article
Engineering, Biomedical
Le Li, Xiang Wang, Bo Yao, Xu Zhang, Ping Zhou
Summary: This study aimed to evaluate the utility of sample entropy (SampEn) of surface electromyographic signals (sEMG) in quantifying neuromuscular changes after spinal cord injury (SCI). The SampEn values after SCI had a significantly greater range than those of the control subjects at the group level. SampEn is a valuable indicator for identifying neuromuscular changes after SCI, and the effect of the IZ on the sEMG examination is particularly noteworthy.
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING
(2023)
