Stimulator of Interferon Genes Promotes Host Resistance Against Pseudomonas aeruginosa Keratitis

Innate Immune Activation by cGMP-AMP Nanoparticles Leads to Potent and Long-Acting Antiretroviral Response against HIV-1

(2017) Chukwuemika Aroh et al.   JOURNAL OF IMMUNOLOGY

Opposing roles of Toll-like receptor and cytosolic DNA-STING signaling pathways for Staphylococcus aureus cutaneous host defense

(2017) Philip O. Scumpia et al.   PLoS Pathogens

The Bacterial Second Messenger Cyclic di-GMP Regulates Brucella Pathogenesis and Leads to Altered Host Immune Response

(2016) Mike Khan et al.   INFECTION AND IMMUNITY

RIG-I-Mediated STING Upregulation Restricts Herpes Simplex Virus 1 Infection

(2016) Yiliu Liu et al.   JOURNAL OF VIROLOGY

cGAS-STING Signaling Regulates Initial Innate Control of Cytomegalovirus Infection

(2016) Chan-Wang J. Lio et al.   JOURNAL OF VIROLOGY

Activation of STING requires palmitoylation at the Golgi

(2016) Kojiro Mukai et al.   Nature Communications

Sensing of HSV-1 by the cGAS–STING pathway in microglia orchestrates antiviral defence in the CNS

(2016) Line S. Reinert et al.   Nature Communications

The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy

(2015) Robert O. Watson et al.   Cell Host & Microbe

Role of the DNA Sensor STING in Protection from Lethal Infection following Corneal and Intracerebral Challenge with Herpes Simplex Virus 1

(2015) Zachary M. Parker et al.   JOURNAL OF VIROLOGY

A STING-dependent innate-sensing pathway mediates resistance to corneal HSV-1 infection via upregulation of the antiviral effector tetherin

(2015) D J Royer et al.   Mucosal Immunology

Suppression of systemic autoimmunity by the innate immune adaptor STING

(2015) Shruti Sharma et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STING-Dependent Type I IFN Production Inhibits Cell-Mediated Immunity to Listeria monocytogenes

(2014) Kristina A. Archer et al.   PLoS Pathogens

Inhibition of the type I immune responses of human monocytes by IFN-α and IFN-β

(2013) Roelof A. de Paus et al.   CYTOKINE

STING/MPYS Mediates Host Defense against Listeria monocytogenes Infection by Regulating Ly6Chi Monocyte Migration

(2013) L. Jin et al.   JOURNAL OF IMMUNOLOGY

β-Catenin promotes host resistance against Pseudomonas aeruginosa keratitis

(2013) Kang Chen et al.   JOURNAL OF INFECTION

Beneficial innate signaling interference for antibacterial responses by a Toll-like receptor-mediated enhancement of the MKP-IRF3 axis

(2013) H. Negishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pivotal Roles of cGAS-cGAMP Signaling in Antiviral Defense and Immune Adjuvant Effects

(2013) X.-D. Li et al.   SCIENCE

Extracellular M. tuberculosis DNA Targets Bacteria for Autophagy by Activating the Host DNA-Sensing Pathway

(2012) Robert O. Watson et al.   CELL

Mycobacterium tuberculosis Triggers Host Type I IFN Signaling To Regulate IL-1  Production in Human Macrophages

(2011) A. Novikov et al.   JOURNAL OF IMMUNOLOGY

TLR4 and TLR5 on Corneal Macrophages Regulate Pseudomonas aeruginosa Keratitis by Signaling through MyD88-Dependent and -Independent Pathways

(2010) Y. Sun et al.   JOURNAL OF IMMUNOLOGY

Topical flagellin protects the injured corneas from Pseudomonas aeruginosa infection

(2010) Ashok Kumar et al.   MICROBES AND INFECTION

ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization

(2009) W. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

(2008) Hiroki Ishikawa et al.   NATURE