Activation of the Regulatory T-Cell/Indoleamine 2,3-Dioxygenase Axis Reduces Vascular Inflammation and Atherosclerosis in Hyperlipidemic Mice

Vaccination against T-cell epitopes of native ApoB100 reduces vascular inflammation and disease in a humanized mouse model of atherosclerosis

(2017) A. Gisterå et al.   JOURNAL OF INTERNAL MEDICINE

Clinical Tolerogenic Dendritic Cells: Exploring Therapeutic Impact on Human Autoimmune Disease

(2017) Brett Eugene Phillips et al.   Frontiers in Immunology

The interplay between cytokines and the Kynurenine pathway in inflammation and atherosclerosis

(2017) Roland Baumgartner et al.   CYTOKINE

Indoleamine 2,3-Dioxygenase-Expressing Aortic Plasmacytoid Dendritic Cells Protect against Atherosclerosis by Induction of Regulatory T Cells

(2016) Tae Jin Yun et al.   Cell Metabolism

Inhibition of indoleamine 2,3-dioxygenase promotes vascular inflammation and increases atherosclerosis in Apoe−/− mice

(2015) Konstantinos A. Polyzos et al.   CARDIOVASCULAR RESEARCH

Modulation of Autoimmunity and Atherosclerosis　– Common Targets and Promising Translational Approaches Against Disease –

(2015) Daniel FJ Ketelhuth et al.   CIRCULATION JOURNAL

The role of the kynurenine pathway of tryptophan metabolism in cardiovascular disease

(2015) K. A. Polyzos et al.   Hamostaseologie

Oxidized Low-Density Lipoprotein–Induced Apoptotic Dendritic Cells as a Novel Therapy for Atherosclerosis

(2015) Vanessa Frodermann et al.   JOURNAL OF IMMUNOLOGY

Indoleamine 2,3-dioxygenase-1 is protective in atherosclerosis and its metabolites provide new opportunities for drug development

(2015) Jennifer E. Cole et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IDO-GCN2 and autophagy in inflammation

(2015) Tracy L. McGaha   Oncotarget

Accumulation of an Endogenous Tryptophan-Derived Metabolite in Colorectal and Breast Cancers

(2015) Paolo Puccetti et al.   PLoS One

Treg Cell Function in Rheumatoid Arthritis Is Compromised by CTLA-4 Promoter Methylation Resulting in a Failure to Activate the Indoleamine 2,3-Dioxygenase Pathway

(2014) Adam P. Cribbs et al.   Arthritis & Rheumatology

Tolerogenic Splenic IDO+Dendritic Cells from the Mice Treated with Induced-Treg Cells Suppress Collagen-Induced Arthritis

(2014) Jie Yang et al.   Journal of Immunology Research

EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update

(2013) Josef S Smolen et al.   ANNALS OF THE RHEUMATIC DISEASES

T Cell-based Therapies for Atherosclerosis

(2013) Daniel Ketelhuth et al.   CURRENT PHARMACEUTICAL DESIGN

T-cell co-stimulation by CD28–CD80/86 and its negative regulator CTLA-4 strongly influence accelerated atherosclerosis development

(2013) M.M. Ewing et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Treg and CTLA-4: Two intertwining pathways to immune tolerance

(2013) Lucy S.K. Walker   JOURNAL OF AUTOIMMUNITY

Indoleamine 2,3-dioxygenase, Tregs and Cancer

(2012) D. H. Munn   CURRENT MEDICINAL CHEMISTRY

Molecular Mechanisms of Treg-Mediated T Cell Suppression

(2012) Angelika Schmidt et al.   Frontiers in Immunology

Immunotherapy With Tolerogenic Apolipoprotein B-100–Loaded Dendritic Cells Attenuates Atherosclerosis in Hypercholesterolemic Mice

(2011) Andreas Hermansson et al.   CIRCULATION

Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells

(2011) Maria T Pallotta et al.   NATURE IMMUNOLOGY

CD4 + CD25 + Foxp3 + Regulatory T Cells Protect the Proinflammatory Activation of Human Umbilical Vein Endothelial Cells

(2010) Shaolin He et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Inhibition of T cell response to native low-density lipoprotein reduces atherosclerosis

(2010) Andreas Hermansson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL

Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation

(2008) Y. Onishi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CTLA-4 Control over Foxp3+ Regulatory T Cell Function

(2008) K. Wing et al.   SCIENCE