Programmed Cell Death Protein 1–PDL1 Interaction Prevents Heart Damage in Chronic Trypanosoma cruzi Infection

Rescue of exhausted CD8 T cells by PD-1–targeted therapies is CD28-dependent

(2017) Alice O. Kamphorst et al.   SCIENCE

Quantifying Memory CD8 T Cells Reveals Regionalization of Immunosurveillance

(2015) Elizabeth M. Steinert et al.   CELL

Randomized Trial of Benznidazole for Chronic Chagas’ Cardiomyopathy

(2015) Carlos A. Morillo et al.   NEW ENGLAND JOURNAL OF MEDICINE

PD-L1hi B cells are critical regulators of humoral immunity

(2015) Adnan R. Khan et al.   Nature Communications

Pentoxifylline Reverses Chronic Experimental Chagasic Cardiomyopathy in Association with Repositioning of Abnormal CD8+ T-Cell Response

(2015) Isabela Resende Pereira et al.   PLoS Neglected Tropical Diseases

Myocardial Gene Expression ofT-bet,GATA-3,Ror-γt,FoxP3, and Hallmark Cytokines in Chronic Chagas Disease Cardiomyopathy: An Essentially Unopposed TH1-Type Response

(2014) Luciana Gabriel Nogueira et al.   MEDIATORS OF INFLAMMATION

Plasma Cytokine Expression Is Associated with Cardiac Morbidity in Chagas Disease

(2014) Giovane Rodrigo Sousa et al.   PLoS One

Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1)

(2013) M. J. Fuller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Ets-1 transcription factor is required for Stat1-mediated T-bet expression and IgG2a class switching in mouse B cells

(2012) H. V. Nguyen et al.   BLOOD

Inhibitory Receptors Are Expressed by Trypanosoma cruzi-Specific Effector T Cells and in Hearts of Subjects with Chronic Chagas Disease

(2012) Rafael J. Argüello et al.   PLoS One

I Diretriz Latino-Americana para o diagnóstico e tratamento da cardiopatia chagásica: resumo executivo

(2011) Jadelson Pinheiro de Andrade et al.   Arquivos Brasileiros de Cardiologia

Regulation of Trypanosoma cruzi-Induced Myocarditis by Programmed Death Cell Receptor 1

(2011) Fredy R. S. Gutierrez et al.   INFECTION AND IMMUNITY

Therapeutic blockade of PD-L1 and LAG-3 rapidly clears established blood-stage Plasmodium infection

(2011) Noah S Butler et al.   NATURE IMMUNOLOGY

The Liver Plays a Major Role in Clearance and Destruction of Blood Trypomastigotes in Trypanosoma cruzi Chronically Infected Mice

(2010) Luiz Roberto Sardinha et al.   PLoS Neglected Tropical Diseases

Infection by the Sylvio X10/4 clone of Trypanosoma cruzi: relevance of a low-virulence model of Chagas' disease

(2009) Cláudio R.F. Marinho et al.   MICROBES AND INFECTION

Enhancing SIV-specific immunity in vivo by PD-1 blockade

(2008) Vijayakumar Velu et al.   NATURE