Inhibitors of Apoptosis Protein Antagonists (Smac Mimetic Compounds) Control Polarization of Macrophages during Microbial Challenge and Sterile Inflammatory Responses

Cotreatment with Smac mimetics and demethylating agents induces both apoptotic and necroptotic cell death pathways in acute lymphoblastic leukemia cells

(2016) Steve Gerges et al.   CANCER LETTERS

Identification and functional analysis of essential, conserved, housekeeping and duplicated genes

(2016) P. V. Parvati Sai Arun et al.   FEBS LETTERS

CD14/TLR4 priming potentially recalibrates and exerts anti-tumor efficacy in tumor associated macrophages in a mouse model of pancreatic carcinoma

(2016) Hridayesh Prakash et al.   Scientific Reports

Metabolic reprogramming in macrophages and dendritic cells in innate immunity

(2015) Beth Kelly et al.   CELL RESEARCH

Immunometabolism governs dendritic cell and macrophage function

(2015) Luke A.J. O’Neill et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Smac mimetics and innate immune stimuli synergize to promote tumor death

(2014) Shawn T Beug et al.   NATURE BIOTECHNOLOGY

Small-molecule SMAC mimetics as new cancer therapeutics

(2014) Longchuan Bai et al.   PHARMACOLOGY & THERAPEUTICS

Low-Dose Irradiation Programs Macrophage Differentiation to an iNOS+/M1 Phenotype that Orchestrates Effective T Cell Immunotherapy

(2013) Felix Klug et al.   CANCER CELL

Hypoxia-Mediated Impairment of the Mitochondrial Respiratory Chain Inhibits the Bactericidal Activity of Macrophages

(2012) Melanie Wiese et al.   INFECTION AND IMMUNITY

HIF-1α is involved in mediating apoptosis resistance to Chlamydia trachomatis-infected cells

(2011) Manu Sharma et al.   CELLULAR MICROBIOLOGY

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

(2011) A. Phillip West et al.   NATURE

Caspase-1 Dependent IL-1β Secretion Is Critical for Host Defense in a Mouse Model of Chlamydia pneumoniae Lung Infection

(2011) Kenichi Shimada et al.   PLoS One

Mitogen-Activated Protein Kinase Phosphatase 2 Regulates the Inflammatory Response in Sepsis

(2010) T. T. Cornell et al.   INFECTION AND IMMUNITY

Deficiency of XIAP Leads to Sensitization forChlamydophila pneumoniaePulmonary Infection and Dysregulation of Innate Immune Response in Mice

(2010) Hridayesh Prakash et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

(2010) Subhra K Biswas et al.   NATURE IMMUNOLOGY

Altering the balance between pathogen containing vacuoles and lysosomes: A lesson from Salmonella

(2010) Amit Lahiri et al.   Virulence

MAP Kinase Phosphatase-2 Plays a Critical Role in Response to Infection by Leishmania mexicana

(2010) Mashael S. Al-Mutairi et al.   PLoS Pathogens

Subversion of Innate Immune Responses by Brucella through the Targeted Degradation of the TLR Signaling Adapter, MAL

(2009) D. Sengupta et al.   JOURNAL OF IMMUNOLOGY

Restriction of Chlamydia pneumoniae replication in human dendritic cell by activation of indoleamine 2,3-dioxygenase

(2009) Florence Njau et al.   MICROBES AND INFECTION

cIAP-1 Controls Innate Immunity to C. pneumoniae Pulmonary Infection

(2009) Hridayesh Prakash et al.   PLoS One

Apoptosis resistance inChlamydia-infected cells: a fate worse than death?

(2008) Manu Sharma et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Chlamydia pneumoniae induces macrophage-derived foam cell formation by up-regulating acyl-coenzyme A: cholesterol acyltransferase 1

(2008) Ping He et al.   MICROBES AND INFECTION