A Reappraisal on the Potential Ability of Human Neutrophils to Express and Produce IL-17 Family Members In Vitro: Failure to Reproducibly Detect It

Sexy again: the renaissance of neutrophils in psoriasis

(2017) Michael P. Schön et al.   EXPERIMENTAL DERMATOLOGY

The importance of being “pure” neutrophils

(2017) Federica Calzetti et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Th-17 regulatory cytokines IL-21, IL-23, and IL-6 enhance neutrophil production of IL-17 cytokines during asthma

(2017) Rabih Halwani et al.   JOURNAL OF ASTHMA

Neutrophils are not the dominant interleukin-17 producer in psoriasis

(2017) Keiichi Yamanaka et al.   JOURNAL OF DERMATOLOGY

IL-17 Signaling: The Yin and the Yang

(2017) Nilesh Amatya et al.   TRENDS IN IMMUNOLOGY

IL-17 Production of Neutrophils Enhances Antibacteria Ability but Promotes Arthritis Development During Mycobacterium tuberculosis Infection

(2017) Shengfeng Hu et al.   EBioMedicine

Interleukin-17–Producing Neutrophils Link Inflammatory Stimuli to Disease Progression by Promoting Angiogenesis in Gastric Cancer

(2016) Tuan-Jie Li et al.   CLINICAL CANCER RESEARCH

Neutrophils from F508del cystic fibrosis patients produce IL-17A and express IL-23 - dependent IL-17RC

(2016) Patricia R. Taylor et al.   CLINICAL IMMUNOLOGY

JAK/STAT regulation of Aspergillus fumigatus corneal infections and IL-6/23-stimulated neutrophil, IL-17, elastase, and MMP9 activity

(2016) Patricia R. Taylor et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Editorial: Fake it ’til you make it: mast cells acquire IL-17 exogenously

(2016) Anna R. Huppler et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Human mast cells capture, store, and release bioactive, exogenous IL-17A

(2016) Troy Noordenbos et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Innate Immune Responses after Airway Epithelial Stimulation with Mycobacterium bovis Bacille-Calmette Guérin

(2016) Erik Tenland et al.   PLoS One

Neutrophils induce proangiogenic T cells with a regulatory phenotype in pregnancy

(2016) Suchita Nadkarni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A pathogenic IFNα, BLyS and IL-17 axis in Systemic Lupus Erythematosus patients

(2016) Patricia López et al.   Scientific Reports

IFNα enhances the production of IL-6 by human neutrophils activated via TLR8

(2016) Maili Zimmermann et al.   Scientific Reports

Keratinocytes and neutrophils are important sources of proinflammatory molecules in hidradenitis suppurativa

(2015) A.L. Lima et al.   BRITISH JOURNAL OF DERMATOLOGY

Evidence that a neutrophil-keratinocyte crosstalk is an early target of IL-17A inhibition in psoriasis

(2015) Kristian Reich et al.   EXPERIMENTAL DERMATOLOGY

IFN-γ induction by neutrophil-derived IL-17A homodimer augments pulmonary antibacterial defense

(2015) S Cai et al.   Mucosal Immunology

Distinctive expression pattern of interleukin-17 cytokine family members in colorectal cancer

(2015) Ahmed Al-Samadi et al.   TUMOR BIOLOGY

Chromatin remodelling and autocrine TNFα are required for optimal interleukin-6 expression in activated human neutrophils

(2015) Maili Zimmermann et al.   Nature Communications

Angels and demons: Th17 cells represent a beneficial response, while neutrophil IL-17 is associated with poor prognosis in squamous cervical cancer

(2015) Simone Punt et al.   OncoImmunology

Innate immune cells express IL-17A/F in acute generalized exanthematous pustulosis and generalized pustular psoriasis

(2014) M. Kakeda et al.   ARCHIVES OF DERMATOLOGICAL RESEARCH

A lack of confirmation with alternative assays questions the validity of IL-17A expression in human neutrophils using immunohistochemistry

(2014) Francesca Tamarozzi et al.   IMMUNOLOGY LETTERS

Interleukin 17 Expression in Peripheral Blood Neutrophils From Fungal Keratitis Patients and Healthy Cohorts in Southern India

(2014) Rajapandian Sivaganesa Karthikeyan et al.   JOURNAL OF INFECTIOUS DISEASES

Innate Immune Cell–Produced IL-17 Sustains Inflammation in Bullous Pemphigoid

(2014) Sébastien Le Jan et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

IL-17A is a novel player in dialysis-induced peritoneal damage

(2014) Raquel Rodrigues-Díez et al.   KIDNEY INTERNATIONAL

Heterogeneous expression pattern of interleukin 17A (IL-17A), IL-17F and their receptors in synovium of rheumatoid arthritis, psoriatic arthritis and osteoarthritis: possible explanation for nonresponse to anti-IL-17 therapy?

(2014) Lisa GM van Baarsen et al.   ARTHRITIS RESEARCH & THERAPY

Comparing cancer vs normal gene expression profiles identifies new disease entities and common transcriptional programs in AML patients

(2013) N. Rapin et al.   BLOOD

Latent Enhancers Activated by Stimulation in Differentiated Cells

(2013) Renato Ostuni et al.   CELL

Cutting Edge: An Inactive Chromatin Configuration at the IL-10 Locus in Human Neutrophils

(2013) N. Tamassia et al.   JOURNAL OF IMMUNOLOGY

In Vivo Induction of Cutaneous Inflammation Results in the Accumulation of Extracellular Trap-Forming Neutrophils Expressing RORγt and IL-17

(2013) Romy R.M.C Keijsers et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Modification of Enhancer Chromatin: What, How, and Why?

(2013) Eliezer Calo et al.   MOLECULAR CELL

Activation of neutrophils by autocrine IL-17A–IL-17RC interactions during fungal infection is regulated by IL-6, IL-23, RORγt and dectin-2

(2013) Patricia R Taylor et al.   NATURE IMMUNOLOGY

Neutrophils Are Essential As A Source Of Il-17 In The Effector Phase Of Arthritis

(2013) Masaki Katayama et al.   PLoS One

Neutrophils produce interleukin-17B in rheumatoid synovial tissue

(2013) V.-P. Kouri et al.   RHEUMATOLOGY

On the cytokines produced by human neutrophils in tumors

(2013) Cristina Tecchio et al.   SEMINARS IN CANCER BIOLOGY

RORγt+IL-17+ neutrophils play a critical role in hepatic ischemia–reperfusion injury

(2013) Zhongming Tan et al.   Journal of Molecular Cell Biology

Effect of IL-17A blockade with secukinumab in autoimmune diseases

(2012) Dhavalkumar D Patel et al.   ANNALS OF THE RHEUMATIC DISEASES

Targeting IL-17 and TH17 cells in chronic inflammation

(2012) Pierre Miossec et al.   NATURE REVIEWS DRUG DISCOVERY

Marking and Quantifying IL-17A-Producing Cells In Vivo

(2012) April E. Price et al.   PLoS One

The Th17 Pathway in Cystic Fibrosis Lung Disease

(2011) Hui-Leng Tan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Importance of Testing Anti-IL-17 Antibodies From Different Suppliers

(2011) Ü. Yapici et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Interleukin-17 expression in neutrophils and Th17 cells in cutaneous T-cell lymphoma associated with neutrophilic infiltrate of the skin

(2011) L. Fontao et al.   BRITISH JOURNAL OF DERMATOLOGY

Application of ChIP-Seq and Related Techniques to the Study of Immune Function

(2011) Daniel L. Northrup et al.   IMMUNITY

Neutrophils Produce Interleukin 17A (IL-17A) in a Dectin-1- and IL-23-Dependent Manner during Invasive Fungal Infection

(2011) Jessica L. Werner et al.   INFECTION AND IMMUNITY

IL-17A as a regulator of neutrophil survival in nasal polyp disease of patients with and without cystic fibrosis

(2011) L. Derycke et al.   Journal of Cystic Fibrosis

Netting Neutrophils Induce Endothelial Damage, Infiltrate Tissues, and Expose Immunostimulatory Molecules in Systemic Lupus Erythematosus

(2011) E. Villanueva et al.   JOURNAL OF IMMUNOLOGY

Mast Cells and Neutrophils Release IL-17 through Extracellular Trap Formation in Psoriasis

(2011) A. M. Lin et al.   JOURNAL OF IMMUNOLOGY

Mechanisms controlling Th17 cytokine expression and host defense

(2011) Jeremy P. McAleer et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Failure to detect production of IL-10 by activated human neutrophils

(2011) Martin S Davey et al.   NATURE IMMUNOLOGY

IL-17A Expression Is Localised to Both Mononuclear and Polymorphonuclear Synovial Cell Infiltrates

(2011) Ellen M. Moran et al.   PLoS One

Interleukin-17 positive cells accumulate in renal allografts during acute rejection and are independent predictors of worse graft outcome

(2011) Ünsal Yapici et al.   TRANSPLANT INTERNATIONAL

Analysis of IL-17+ cells in facet joints of patients with spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-mediated adaptive immune response

(2011) Heiner Appel et al.   ARTHRITIS RESEARCH & THERAPY

Identification of Cells Expressing IL-17A and IL-17F in the Lungs of Patients With COPD

(2010) Amanda Eustace et al.   CHEST

Raised interleukin-17 is immunolocalised to neutrophils in cystic fibrosis lung disease

(2010) M. Brodlie et al.   EUROPEAN RESPIRATORY JOURNAL

The NIH Roadmap Epigenomics Mapping Consortium

(2010) Bradley E Bernstein et al.   NATURE BIOTECHNOLOGY

Overrepresentation of IL-17A and IL-22 Producing CD8 T Cells in Lesional Skin Suggests Their Involvement in the Pathogenesis of Psoriasis

(2010) Pieter C. M. Res et al.   PLoS One

Evidence for a cross-talk between human neutrophils and Th17 cells

(2009) M. Pelletier et al.   BLOOD

IL-17 produced by neutrophils regulates IFN-γ–mediated neutrophil migration in mouse kidney ischemia-reperfusion injury

(2009) Li Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Differential expression of interleukin-17 family cytokines in intact and complicated human atherosclerotic plaques

(2009) Onno J de Boer et al.   JOURNAL OF PATHOLOGY

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

The interleukin-17 pathway is involved in human alcoholic liver disease

(2008) Arnaud Lemmers et al.   HEPATOLOGY

MPO-ANCA induces IL-17 production by activated neutrophils in vitro via its Fc region- and complement-dependent manner

(2008) Akiyoshi Hoshino et al.   JOURNAL OF AUTOIMMUNITY