Article
Clinical Neurology
Hiroyuki Inose, Tsuyoshi Kato, Shoichi Ichimura, Hiroaki Nakamura, Masatoshi Hoshino, Daisuke Togawa, Toru Hirano, Yasuaki Tokuhashi, Tetsuro Ohba, Hirotaka Haro, Takashi Tsuji, Kimiaki Sato, Yutaka Sasao, Masahiko Takahata, Koji Otani, Suketaka Momoshima, Kunihiko Takahashi, Masato Yuasa, Takashi Hirai, Toshitaka Yoshii, Atsushi Okawa
Summary: Women with fresh OVF are at higher risk for subsequent vertebral fracture within the next year. Severe low back pain and use of soft braces are associated with higher risk of subsequent vertebral fractures. Therefore, more attention may be needed for the occurrence of subsequent vertebral fractures in patients treated with these risk factors after OVFs.
EUROPEAN SPINE JOURNAL
(2021)
Article
Anesthesiology
Chengyue Ji, Yuluo Rong, Jiaxing Wang, Shunzhi Yu, Guoyong Yin, Jin Fan, Pengyu Tang, Dongdong Jiang, Wei Liu, Fangyi Gong, Xuhui Ge, Weihua Cai
Summary: In the aging population, secondary vertebral compression fractures following primary osteoporotic vertebral compression fractures are a significant concern. Age, history of nonspinal fractures, and Hounsfield units value of L1 were identified as independent risk factors associated with secondary vertebral compression fractures.
Article
Clinical Neurology
Sang Hoon Hwang, Pyung Goo Cho, Kyoung-Tae Kim, Keung Nyun Kim, Sang Hyun Kim, Sung Hyun Noh
Summary: This study aimed to identify risk factors for a second OVCF after a first OVCF. A retrospective observational study was conducted, enrolling 178 patients from a single institution who had their first OVCF between January 1, 2000 and December 31, 2019. Patient demographics, bone mineral density, and pelvic parameters were observed for all cases.
Article
Clinical Neurology
Jin-Sung Park, Ye-Soo Park
Summary: A retrospective cohort study of 205 patients who underwent vertebroplasty for OVCF found a significant difference in the time of occurrence between AVF and RVF, with different risk factors identified for each. Thoracolumbar junction vertebroplasty was a risk factor for AVF, while sagittal imbalance was a risk factor for both AVF and RVF.
Article
Geriatrics & Gerontology
Christian Pfeifle, Petr Kohut, Jan-Sven Jarvers, Ulrich J. Spiegl, Christoph-Eckhard Heyde, Georg Osterhoff
Summary: This study assessed the impact of time to surgery on 1-year survival in patients with osteoporotic vertebral compression fractures. The findings showed that time-to-surgery had no significant effect on one-year mortality in geriatric patients with these fractures, suggesting that treatment decisions should be individualized.
Review
Endocrinology & Metabolism
M. Barake, R. El Eid, S. Ajjour, M. Chakhtoura, L. Meho, T. Mahmoud, J. Atieh, A. M. Sibai, G. El-Hajj Fuleihan
Summary: The study revealed that Asia is projected to have the largest proportion of osteoporotic fractures worldwide, while data from the Middle East is scarce. Most patients in Arab League countries with osteoporotic fractures were not tested or treated, with high mortality rates observed at 1 to 3 years post-fracture.
OSTEOPOROSIS INTERNATIONAL
(2021)
Review
Clinical Neurology
Max J. Scheyerer, Ulrich J. A. Spiegl, Sebastian Grueninger, Frank Hartmann, Sebastian Katscher, Georg Osterhoff, Mario Perl, Matthias Pumberger, Gregor Schmeiser, Bernhard W. Ullrich, Klaus J. Schnake
Summary: This systematic review identified various risk factors that predict treatment failure in conservatively treated osteoporotic fractures, including age, bone density, BMI, and specific radiological findings. In cases of treatment failure, additional treatment options and surgical treatment strategies should be considered besides follow-up examinations.
GLOBAL SPINE JOURNAL
(2022)
Article
Orthopedics
Marziyeh Rajabi, Afshin Ostovar, Ali Akbari Sari, Sayed Mahmoud Sajjadi-Jazi, Noushin Fahimfar, Bagher Larijani, Rajabali Daroudi
Summary: This study estimated the direct costs of hip, vertebral, and forearm fractures in the first year after fracture incidence in Iran, finding that the direct cost of osteoporotic fractures in Iran is high. The findings may be useful for economic evaluation and estimating the economic burden of osteoporotic fractures in Iran.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Orthopedics
Zhi Chen, Chenyang Song, Min Chen, Hongxiang Li, Yusong Ye, Wenge Liu
Summary: This study identified risk factors for subsequent fractures in the thoracolumbar segment after vertebral augmentation, including previous fracture, intravertebral cleft, fatty infiltration of psoas, and body angle restoration rate. Refractures were more likely to occur when the body angle restoration rate exceeded 0.350.
BMC MUSCULOSKELETAL DISORDERS
(2021)
Article
Surgery
Xiangcheng Gao, Jinpeng Du, Lin Gao, Dingjun Hao, Hua Hui, Baorong He, Liang Yan
Summary: High restoration of Cobb angle, cement leakage (anterior edge), small degree of bone cement interweaving, non-targeted location of bone cement, short duration of brace wearing and non-postoperative osteoporosis treatment were identified as independent risk factors for bone cement displacement after percutaneous vertebral augmentation (PVA).
FRONTIERS IN SURGERY
(2022)
Article
Orthopedics
Kui Zhang, Jiang She, Yandong Zhu, Wenji Wang, Erliang Li, Ding Ma
Summary: The study identified different risk factors for various types of cement leakage, which may help reduce the rate of leakage.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2021)
Article
Endocrinology & Metabolism
Sang-Min Park, Sung Jun Go, Heesoo Han, Jung Wee Park, Young-Kyun Lee, Ho-Joong Kim, Jin S. Yeom, Kyung-Hoi Koo
Summary: This study evaluated the incidence of subsequent vertebral fractures in elderly hip fracture patients after surgical treatment and identified risk factors for these fractures. The findings showed that subsequent vertebral fractures did not affect mortality rates after hip fractures, with age, low BMI, and comorbidities being significant risk factors for mortality. Timely management is important for preventing subsequent vertebral fractures in these patients.
JOURNAL OF BONE AND MINERAL METABOLISM
(2021)
Review
Clinical Neurology
Shinji Takahashi, Hiroyuki Inose, Koji Tamai, Masayoshi Iwamae, Hidetomi Terai, Hiroaki Nakamura
Summary: Osteoporotic vertebral fractures (OVFs) can be treated with vertebral augmentation, but there are risks of complications and revision surgery. The risks for revision surgery include age, gender, and diabetes. Current evidence lacks substantial guidance for treatment strategies, and alternative surgeries and conservative treatments should be considered for high-risk patients.
Article
Anesthesiology
Wu Tao, Wang Biao, Chen Xingmei, Qin Hu, Sun Jinpeng, Gu Yue, Liu Jun
Summary: The study retrospectively reviewed clinical data of OVCF patients undergoing PKP from January 2016 to December 2020. It found that factors such as BMD, kyphosis angle, cement distribution, and adjacent disc degeneration may predict the occurrence of AVF after PKP. Patients with low BMD, large kyphosis angle, uneven cement distribution, and disc degeneration were at higher risk for AVF.
Article
Orthopedics
Feng Wang, Rui Sun, Shao-Dong Zhang, Xiao-Tao Wu
Summary: This study aimed to compare the risk factors, vertebral compression degree, and back pain characteristics between thoracolumbar osteoporotic vertebral compression fractures (TL-OVCF) and non-thoracolumbar OVCF (nTL-OVCF). The results showed that TL-OVCF had a higher risk than nTL-OVCF, and nTL-OVCF was not associated with female gender, apparent spine trauma, or poor bone mineral density but tended to cause longer duration of pre-hospital back pain.
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH
(2023)
Article
Health Care Sciences & Services
Jing Wu, Jaydeep Das, Manik Kalra, Barbara Ratto
Summary: This study systematically reviewed the literature and found that dabrafenib + trametinib significantly prolongs survival in previously untreated melanoma patients, establishing it as one of the preferred treatment options.
JOURNAL OF COMPARATIVE EFFECTIVENESS RESEARCH
(2021)
Article
Endocrinology & Metabolism
Xiaoning He, Yawen Zhang, Yan Zhou, Chaohui Dong, Jing Wu
Summary: This study aimed to provide patient-level cost estimates of managing complications in newly diagnosed type 2 diabetes mellitus (T2DM) patients in China. After 7 years, a high percentage of patients at risk had developed nephropathy and neuropathy. The immediate and long-term costs for specific complications were examined, highlighting the substantial economic burden on the Chinese healthcare system.
Article
Environmental Sciences
Tianfu Gao, Jia Liu, Jing Wu
Summary: The combination therapy of dabrafenib plus trametinib has been shown to increase patient life expectancy and quality-adjusted life years compared to vemurafenib, with a favorable cost-effectiveness profile in China.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Environmental Sciences
Chengyu Liu, Jing Wu, Zheng Chang
Summary: This study found that in recent years, the prevalence of hepatocellular carcinoma in China has been increasing annually, while the incidence remains stable and the mortality rate is decreasing. Age, period, and birth cohort have significant effects on the epidemiological trend of hepatocellular carcinoma.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Pharmacology & Pharmacy
Mingyue Zhao, Peng Nie, Jing Wu
Summary: This study examined the price elasticity of medicine demand in different therapeutic drug categories and types in China, finding variations in elasticity across drug categories and the impact of quality differences, unfair competition, and illegal rebates on price elasticity. The results showed that anti-tumor and CVD drugs had the least elasticity, while antimicrobial drugs had the most elasticity. This study highlights the role of disease type and drug quality in shaping price elasticity in the Chinese medicine market.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Economics
Shitong Xie, Jing Wu, Feng Xie
Summary: This study provides population norms for EQ-5D-5L and SF-6Dv2 among the Chinese general population, and identifies the impact of social-demographic characteristics and chronic conditions on utility values. These norms can serve as references for economic evaluations and healthcare decision-making in China.
APPLIED HEALTH ECONOMICS AND HEALTH POLICY
(2022)
Article
Public, Environmental & Occupational Health
Jing Wu, Chengyu Liu, Fengmei Wang
Summary: This study reveals that HCC patients covered by URRBMI may have worse survival than patients covered by UEBMI. Further efforts are warranted to understand healthcare disparities for patients covered by different basic medical insurance in China.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Public, Environmental & Occupational Health
Shan Jiang, Yitong Wang, Junwen Zhou, Yawen Jiang, Gordon Guo-En Liu, Jing Wu
Summary: The inclusion of future unrelated medical costs can improve the internal and external consistency of economic evaluation and the comparability of results between different jurisdictions. However, more research is needed to further explore this issue.
Article
Economics
Dan Cai, Si Shi, Shan Jiang, Lei Si, Jing Wu, Yawen Jiang
Summary: The study aimed to estimate the cost-effective threshold (CET) of a quality-adjusted life year (QALY) in China as 1.5 times of GDP per capita, which should be benchmarked for future ICER-based coverage decisions.
EUROPEAN JOURNAL OF HEALTH ECONOMICS
(2022)
Article
Health Care Sciences & Services
Shitong Xie, Jing Wu, Gang Chen
Summary: This study evaluates and compares the test-retest reliability of discrete choice experiments with duration and time trade-off in the Chinese SF-6Dv2 valuation study. The results show that both approaches have relatively stable consistency at the individual and aggregate level.
QUALITY OF LIFE RESEARCH
(2022)
Article
Economics
Jia Liu, Xiaoning He, Jing Wu
Summary: The study evaluated the cost-effectiveness of Budesonide/glycopyrrolate/formoterol fumarate (BGF) compared to LAMA/LABA therapies for patients with moderate to very severe COPD in China. Results showed that BGF treatment led to fewer exacerbations and was a cost-effective option, improving outcomes compared to the composite comparator.
APPLIED HEALTH ECONOMICS AND HEALTH POLICY
(2022)
Article
Public, Environmental & Occupational Health
Jiahui Zhang, Xiaoning He, Jing Wu
Summary: In Chinese chronic kidney disease patients, hyperkalemia is associated with substantially increased clinical and economic burdens that are driven by the short period following the hyperkalemia events, which strengthens calls for sufficient supervision and management of serum potassium.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Health Care Sciences & Services
Gordon G. Liu, Jing Wu, Xiaoning He, Yawen Jiang
Summary: This review explores the initiatives taken by the Chinese government to improve access to innovative medicines through regulatory and reimbursement measures, resulting in accelerated drug launches and expanded coverage. However, standardized and transparent evidence appraisal processes are still needed.
VALUE IN HEALTH REGIONAL ISSUES
(2022)
Letter
Psychiatry
Shitong Xie, Ying Zhu, Xiaoqin Wang, Jing Wu, Qi Wang
Article
Economics
Fan Yang, Shan Jiang, Xiao-ning He, Hong-chao Li, Hong-yan Wu, Tian-tian Zhang, Jing Wu
Summary: The content validity of EQ-5D-5L among rural Chinese was studied, revealing that participants found the domains of 'mobility', 'self-care', and 'usual activities' easy to understand, but reported confusion in 'pain/discomfort' and 'anxiety/depression'. Suggestions were made to reduce response levels and provide alternative wordings for 'slight'.
PHARMACOECONOMICS-OPEN
(2021)