Sequentially Triggered Nanoparticles with Tumor Penetration and Intelligent Drug Release for Pancreatic Cancer Therapy

The Methylene Alkoxy Carbamate Self-Immolative Unit: Utilization for the Targeted Delivery of Alcohol-Containing Payloads with Antibody-Drug Conjugates

(2016) Robert V. Kolakowski et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synergistic targeting tenascin C and neuropilin-1 for specific penetration of nanoparticles for anti-glioblastoma treatment

(2016) Ting Kang et al.   BIOMATERIALS

Generation of an in vitro 3D PDAC stroma rich spheroid model

(2016) Matthew J. Ware et al.   BIOMATERIALS

Drug Release is Determined by the Chain Length of Fatty Acid-Conjugated Anticancer Agent as One Component of Nano-Prodrug

(2016) Yoshitaka Koseki et al.   BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN

Paclitaxel-Loaded Mixed Micelles Enhance Ovarian Cancer Therapy through Extracellular pH-Triggered PEG Detachment and Endosomal Escape

(2016) Haijun Zhao et al.   MOLECULAR PHARMACEUTICS

Generation of Homogenous Three-Dimensional Pancreatic Cancer Cell Spheroids Using an Improved Hanging Drop Technique

(2016) Matthew J. Ware et al.   TISSUE ENGINEERING PART C-METHODS

Folate-modified Chitosan Nanoparticles Containing the IP-10 Gene Enhance Melanoma-specific Cytotoxic CD8+CD28+ T Lymphocyte Responses

(2016) Jian He et al.   Theranostics

Chemophototherapy: An Emerging Treatment Option for Solid Tumors

(2016) Dandan Luo et al.   Advanced Science

Cell Microenvironment-Controlled Antitumor Drug Releasing-Nanomicelles for GLUT1-Targeting Hepatocellular Carcinoma Therapy

(2015) Yubo Guo et al.   ACS Applied Materials & Interfaces

Size Changeable Nanocarriers with Nuclear Targeting for Effectively Overcoming Multidrug Resistance in Cancer Therapy

(2015) Xing Guo et al.   ADVANCED MATERIALS

Magnetic resonance-guided regional gene delivery strategy using a tumor stroma-permeable nanocarrier for pancreatic cancer

(2015) Xiaolin Wang et al.   International Journal of Nanomedicine

Dimeric Drug Polymeric Nanoparticles with Exceptionally High Drug Loading and Quantitative Loading Efficiency

(2015) Kaimin Cai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Diverse cellular and organismal functions of the lysosomal thiol reductase GILT

(2015) Matthew P. Rausch et al.   MOLECULAR IMMUNOLOGY

Redox-responsive self-assembled chain-shattering polymeric therapeutics

(2015) Kaimin Cai et al.   Biomaterials Science

Smart Nanodevice Combined Tumor-Specific Vector with Cellular Microenvironment-Triggered Property for Highly Effective Antiglioma Therapy

(2014) Kun Shao et al.   ACS Nano

Light-Induced Cytosolic Activation of Reduction-Sensitive Camptothecin-Loaded Polymeric Micelles for Spatiotemporally Controlled in Vivo Chemotherapy

(2014) Hung-Chi Yen et al.   ACS Nano

Dual-Responsive Polymer Micelles for Target-Cell-Specific Anticancer Drug Delivery

(2014) Xing Guo et al.   CHEMISTRY OF MATERIALS

Lumbar Intervertebral Disc Puncture under C-arm Fluoroscopy: a New Rat Model of Lumbar Intervertebral Disc Degeneration

(2014) Dapeng Li et al.   EXPERIMENTAL ANIMALS

Enzyme-Responsive Cell-Penetrating Peptide Conjugated Mesoporous Silica Quantum Dot Nanocarriers for Controlled Release of Nucleus-Targeted Drug Molecules and Real-Time Intracellular Fluorescence Imaging of Tumor Cells

(2014) Jinming Li et al.   Advanced Healthcare Materials

Targeting and Microenvironment-Responsive Lipid Nanocarrier for the Enhancement of Tumor Cell Recognition and Therapeutic Efficiency

(2014) Wei Gao et al.   Advanced Healthcare Materials

Theranostic Nanoparticles with Controlled Release of Gemcitabine for Targeted Therapy and MRI of Pancreatic Cancer

(2013) Gee Young Lee et al.   ACS Nano

Two-Wave Nanotherapy To Target the Stroma and Optimize Gemcitabine Delivery To a Human Pancreatic Cancer Model in Mice

(2013) Huan Meng et al.   ACS Nano

Cancer nanotechnology: The impact of passive and active targeting in the era of modern cancer biology

(2013) Nicolas Bertrand et al.   ADVANCED DRUG DELIVERY REVIEWS

Chain-Shattering Polymeric Therapeutics with On-Demand Drug-Release Capability

(2013) Yanfeng Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Tumor targeting and microenvironment-responsive nanoparticles for gene delivery

(2013) Shixian Huang et al.   BIOMATERIALS

Cancer statistics, 2013

(2013) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Increased Survival in Pancreatic Cancer with nab-Paclitaxel plus Gemcitabine

(2013) Daniel D. Von Hoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

The EPR effect for macromolecular drug delivery to solid tumors: Improvement of tumor uptake, lowering of systemic toxicity, and distinct tumor imaging in vivo

(2012) Hiroshi Maeda et al.   ADVANCED DRUG DELIVERY REVIEWS

Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma

(2012) Paolo P. Provenzano et al.   CANCER CELL

The role of stroma in pancreatic cancer: diagnostic and therapeutic implications

(2012) Mert Erkan et al.   Nature Reviews Gastroenterology & Hepatology

Targeting human epidermal growth factor receptor 2 by a cell-penetrating peptide–affibody bioconjugate

(2011) Srinath Govindarajan et al.   BIOMATERIALS

Gemcitabine Plusnab-Paclitaxel Is an Active Regimen in Patients With Advanced Pancreatic Cancer: A Phase I/II Trial

(2011) Daniel D. Von Hoff et al.   JOURNAL OF CLINICAL ONCOLOGY

Stromal biology and therapy in pancreatic cancer

(2010) A. Neesse et al.   GUT

Advanced pancreatic carcinoma: current treatment and future challenges

(2010) Anastasios Stathis et al.   Nature Reviews Clinical Oncology

Targeted delivery using inorganic nanosystem

(2009) Priyabrata Mukherjee   ADVANCED DRUG DELIVERY REVIEWS

Protein Delivery with Transportans Is Mediated by Caveolae Rather Than Flotillin-Dependent Pathways

(2009) Pille Säälik et al.   BIOCONJUGATE CHEMISTRY

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

(2009) K. P. Olive et al.   SCIENCE

Proline-rich, amphipathic cell-penetrating peptides

(2007) Sílvia Pujals et al.   ADVANCED DRUG DELIVERY REVIEWS