Crystal structure of pyrrolizidine alkaloid N-oxygenase from the grasshopper Zonocerus variegatus

Polycyclic Ketone Monooxygenase from the Thermophilic Fungus Thermothelomyces thermophila: A Structurally Distinct Biocatalyst for Bulky Substrates

(2017) Maximilian J. L. J. Fürst et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Characterization and Crystal Structure of a Robust Cyclohexanone Monooxygenase

(2016) Elvira Romero et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structural and Catalytic Characterization of a Fungal Baeyer-Villiger Monooxygenase

(2016) Felix Martin Ferroni et al.   PLoS One

An Unprecedented NADPH Domain Conformation in Lysine Monooxygenase NbtG Provides Insights into Uncoupling of Oxygen Consumption from Substrate Hydroxylation

(2015) Claudia Binda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystallographic Evidence of Drastic Conformational Changes in the Active Site of a Flavin-Dependent N-Hydroxylase

(2014) Jeremy W. Setser et al.   BIOCHEMISTRY

Exploring nicotinamide cofactor promiscuity in NAD(P)H-dependent flavin containing monooxygenases (FMOs) using natural variation within the phosphate binding loop. Structure and activity of FMOs from Cellvibrio sp. BR and Pseudomonas stutzeri NF13

(2014) Chantel N. Jensen et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Deciphering key features in protein structures with the new ENDscript server

(2014) Xavier Robert et al.   NUCLEIC ACIDS RESEARCH

C4a-Hydroperoxyflavin Formation in N-Hydroxylating Flavin Monooxygenases Is Mediated by the 2′-OH of the Nicotinamide Ribose of NADP+

(2013) Reeder Robinson et al.   BIOCHEMISTRY

Cloning, Baeyer-Villiger Biooxidations, and Structures of the Camphor Pathway 2-Oxo-Δ3-4,5,5-Trimethylcyclopentenylacetyl-Coenzyme A Monooxygenase of Pseudomonas putida ATCC 17453

(2012) Hannes Leisch et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Structural Insight into the Mechanism of Oxygen Activation and Substrate Selectivity of Flavin-Dependent N-Hydroxylating Monooxygenases

(2012) Stefano Franceschini et al.   BIOCHEMISTRY

A Flavoprotein Monooxygenase that Catalyses a Baeyer-Villiger Reaction and Thioether Oxidation Using NADH as the Nicotinamide Cofactor

(2012) Chantel N. Jensen et al.   CHEMBIOCHEM

Exploring the Structural Basis of Substrate Preferences in Baeyer-Villiger Monooxygenases

(2012) Stefano Franceschini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Substrate-Bound Crystal Structure of a Baeyer–Villiger Monooxygenase Exhibits a Criegee-like Conformation

(2012) Brahm J. Yachnin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Independent Recruitment of a Flavin-Dependent Monooxygenase for Safe Accumulation of Sequestered Pyrrolizidine Alkaloids in Grasshoppers and Moths

(2012) Linzhu Wang et al.   PLoS One

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Two Structures of anN-Hydroxylating Flavoprotein Monooxygenase

(2011) Jose Olucha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LigPlot+: Multiple Ligand–Protein Interaction Diagrams for Drug Discovery

(2011) Roman A. Laskowski et al.   Journal of Chemical Information and Modeling

Structural and functional analysis of bacterial flavin-containing monooxygenase reveals its ping-pong-type reaction mechanism

(2011) Hyo Je Cho et al.   JOURNAL OF STRUCTURAL BIOLOGY

Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega

(2011) F. Sievers et al.   Molecular Systems Biology

Evolutionary recruitment of a flavin-dependent monooxygenase for stabilization of sequestered pyrrolizidine alkaloids in arctiids

(2011) Dorothee Langel et al.   PHYTOCHEMISTRY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Flavin-Dependent Monooxygenases as a Detoxification Mechanism in Insects: New Insights from the Arctiids (Lepidoptera)

(2010) Sven Sehlmeyer et al.   PLoS One

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Molecular phylogeny, long-term evolution, and functional divergence of flavin-containing monooxygenases

(2009) Da Cheng Hao et al.   GENETICA

Crystal Structures of Cyclohexanone Monooxygenase Reveal Complex Domain Movements and a Sliding Cofactor

(2009) I. Ahmad Mirza et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pyrrolizidine alkaloids sequestered and stored by the aposematic grasshopper, Zonocerus variegatus

(2009) E. Bernays et al.   JOURNAL OF ZOOLOGY

Flavin-containing monooxygenases: mutations, disease and drug response

(2008) I PHILLIPS et al.   TRENDS IN PHARMACOLOGICAL SCIENCES