Microarray gene expression profiling in colorectal (HCT116) and hepatocellular (HepG2) carcinoma cell lines treated with Melicope ptelefolia leaf extract reveals transcriptome profiles exhibiting anticancer activity

Census and evaluation of p53 target genes

(2017) M Fischer   ONCOGENE

GINS2 is a novel prognostic biomarker and promotes tumor progression in early-stage cervical cancer

(2017) Fei Ouyang et al.   ONCOLOGY REPORTS

TOP2A , HELLS , ATAD2 , and TET3 Are Novel Prognostic Markers in Renal Cell Carcinoma

(2017) Dong Chen et al.   UROLOGY

Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies

(2016) Giuseppa Pistritto et al.   Aging-US

Chromatin Remodeling Factor LSH Drives Cancer Progression by Suppressing the Activity of Fumarate Hydratase

(2016) Xiaozhen He et al.   CANCER RESEARCH

Pharmaceutically inhibiting polo-like kinase 1 exerts a broad anti-tumour activity in retinoblastoma cell lines

(2016) Melanie Schwermer et al.   CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

MCM: one ring to rule them all

(2016) Tom D Deegan et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Lupeol evokes anticancer effects in oral squamous cell carcinoma by inhibiting oncogenic EGFR pathway

(2016) Sanchita Rauth et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

MCM10 overexpression implicates adverse prognosis in urothelial carcinoma

(2016) Wei-Ming Li et al.   Oncotarget

Lead Phytochemicals for Anticancer Drug Development

(2016) Sukhdev Singh et al.   Frontiers in Plant Science

Downregulation of YAP-dependent Nupr1 promotes tumor-repopulating cell growth in soft matrices

(2016) Q Jia et al.   Oncogenesis

Molecular Mechanisms of Apoptosis and Roles in Cancer Development and Treatment

(2015) Samira Goldar et al.   Asian Pacific Journal of Cancer Prevention

The BCL-2 protein family, BH3-mimetics and cancer therapy

(2015) A R D Delbridge et al.   CELL DEATH AND DIFFERENTIATION

Cell cycle regulation of human DNA repair and chromatin remodeling genes

(2015) Robin Mjelle et al.   DNA REPAIR

Global gene expression profiling using heterologous DNA microarrays to analyze alterations in the transcriptome of Mus spretus mice living in a heavily polluted environment

(2015) Julia Ruiz-Laguna et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Advanced targeted therapies in cancer: Drug nanocarriers, the future of chemotherapy

(2015) Edgar Pérez-Herrero et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Targeting Mitosis in Cancer: Emerging Strategies

(2015) Carmen Dominguez-Brauer et al.   MOLECULAR CELL

Targeting the DNA Damage Response in Cancer

(2015) Mark J. O’Connor   MOLECULAR CELL

RBEL1 is required for osteosarcoma cell proliferation via inhibiting retinoblastoma 1

(2015) HONGHUI TANG et al.   Molecular Medicine Reports

The history and future of targeting cyclin-dependent kinases in cancer therapy

(2015) Uzma Asghar et al.   NATURE REVIEWS DRUG DISCOVERY

Targeting Cyclin-Dependent Kinases and Cell Cycle Progression in Human Cancers

(2015) Loredana Santo et al.   SEMINARS IN ONCOLOGY

Oleanolic acid inhibits cell survival and proliferation of prostate cancer cells in vitro and in vivo through the PI3K/Akt pathway

(2015) Xuechao Li et al.   TUMOR BIOLOGY

The BCL2 Family: Key Mediators of the Apoptotic Response to Targeted Anticancer Therapeutics

(2015) A. N. Hata et al.   Cancer Discovery

Apoptosis induced by temozolomide and nimustine in glioblastoma cells is supported by JNK/c-Jun-mediated induction of the BH3-only protein BIM

(2015) Maja T. Tomicic et al.   Oncotarget

Minichromosome Maintenance (MCM) Family as potential diagnostic and prognostic tumor markers for human gliomas

(2014) Cong Hua et al.   BMC CANCER

High GINS2 transcript level predicts poor prognosis and correlates with high histological grade and endocrine therapy resistance through mammary cancer stem cells in breast cancer patients

(2014) Ming Zheng et al.   BREAST CANCER RESEARCH AND TREATMENT

RABL6A Promotes G1-S Phase Progression and Pancreatic Neuroendocrine Tumor Cell Proliferation in an Rb1-Dependent Manner

(2014) J. Hagen et al.   CANCER RESEARCH

Targeting DNA damage response in cancer therapy

(2014) Noriko Hosoya et al.   CANCER SCIENCE

Analysis of TP53 Mutation Status in Human Cancer Cell Lines: A Reassessment

(2014) Bernard Leroy et al.   HUMAN MUTATION

DNA Damage Response Genes and the Development of Cancer Metastasis

(2014) Constantinos G. Broustas et al.   RADIATION RESEARCH

The Mcm2-7 Replicative Helicase: A Promising Chemotherapeutic Target

(2014) Nicholas E. Simon et al.   Biomed Research International

Molecular functions of the iron-regulated metastasis suppressor, NDRG1, and its potential as a molecular target for cancer therapy

(2013) Bernard A. Fang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

c-Jun-mediated anticancer mechanisms of tylophorine

(2013) Cheng-Wei Yang et al.   CARCINOGENESIS

Identification of ribonucleotide reductase M2 as a potential target for pro-senescence therapy in epithelial ovarian cancer

(2013) Katherine M Aird et al.   CELL CYCLE

Investigation of the Antiproliferative Action of the Quinoline Alkaloids Kokusaginine and Skimmianine on Human Cell Lines

(2013) Judit Molnar et al.   Current Signal Transduction Therapy

Negative regulation of p53 by Ras superfamily protein RBEL1A

(2013) K. Lui et al.   JOURNAL OF CELL SCIENCE

The role of NDRG1 in the pathology and potential treatment of human cancers

(2013) Dong-Hun Bae et al.   JOURNAL OF CLINICAL PATHOLOGY

Over Expression of Minichromosome Maintenance Genes is Clinically Correlated to Cervical Carcinogenesis

(2013) Mitali Das et al.   PLoS One

Integrating gene expression and protein-protein interaction network to prioritize cancer-associated genes

(2012) Chao Wu et al.   BMC BIOINFORMATICS

The retinoblastoma family of proteins and their regulatory functions in the mammalian cell division cycle

(2012) Shauna A Henley et al.   Cell Division

Skp2 is a Promising Therapeutic Target in Breast Cancer

(2012) Zhiwei Wang et al.   Frontiers in Oncology

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Function of cyclins in regulating the mitotic and meiotic cell cycles in male germ cells

(2011) Debra J. Wolgemuth   CELL CYCLE

The SNF2-like helicase HELLS mediates E2F3-dependent transcription and cellular transformation

(2011) Björn von Eyss et al.   EMBO JOURNAL

Apoptosis in cancer: from pathogenesis to treatment

(2011) Rebecca SY Wong   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Linking expression of FOXM1, CEP55 and HELLS to tumorigenesis in oropharyngeal squamous cell carcinoma

(2011) Jeffrey R. Janus et al.   LARYNGOSCOPE

Impacting tumor cell-fate by targeting the inhibitor of apoptosis protein survivin

(2011) Ronan J Kelly et al.   Molecular Cancer

Metabolic genes in cancer: Their roles in tumor progression and clinical implications

(2010) Eiji Furuta et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Chemopreventive potential of β-Sitosterol in experimental colon cancer model - an In vitro and In vivo study

(2010) Albert A Baskar et al.   BMC Complementary and Alternative Medicine

Towards a knowledge-based Human Protein Atlas

(2010) Mathias Uhlen et al.   NATURE BIOTECHNOLOGY

Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy

(2010) Klaus Strebhardt   NATURE REVIEWS DRUG DISCOVERY

Stress-inducible Protein p8 Is Involved in Several Physiological and Pathological Processes

(2009) Sandro Goruppi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PUMA, a potent killer with or without p53

(2009) J Yu et al.   ONCOGENE

Growth arrest and DNA damage-45 alpha (GADD45α)

(2008) A. Rosemary Siafakas et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Cyclin-dependent kinases and cell-cycle transitions: does one fit all?

(2008) Helfrid Hochegger et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

JNK signaling in apoptosis

(2008) D N Dhanasekaran et al.   ONCOGENE