Quality control of mRNAs at the entry of the nuclear pore: Cooperation in a complex molecular system

Nuclear retention of mRNAs – quality control, gene regulation and human disease

(2018) Marius Wegener et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The Nuclear Pore Complex as a Flexible and Dynamic Gate

(2016) Kevin E. Knockenhauer et al.   CELL

On the Nuclear Pore Complex and Its Roles in Nucleo-Cytoskeletal Coupling and Mechanobiology

(2016) M. Soheilypour et al.   Cellular and Molecular Bioengineering

The LINC and NPC relationship – it's complicated!

(2016) Zeinab Jahed et al.   JOURNAL OF CELL SCIENCE

mRNA quality control is bypassed for immediate export of stress-responsive transcripts

(2016) Gesa Zander et al.   NATURE

Global analysis of pre-mRNA subcellular localization following splicing inhibition by spliceostatin A

(2016) Rei Yoshimoto et al.   RNA

Dynamic Encounters of Genes and Transcripts with the Nuclear Pore

(2016) Rakefet Ben-Yishay et al.   TRENDS IN GENETICS

Regulation of RNA-binding proteins affinity to export receptors enables the nuclear basket proteins to distinguish and retain aberrant mRNAs

(2016) M. Soheilypour et al.   Scientific Reports

In vivo single-particle imaging of nuclear mRNA export in budding yeast demonstrates an essential role for Mex67p

(2015) Carlas Smith et al.   JOURNAL OF CELL BIOLOGY

The nuclear basket mediates perinuclear mRNA scanning in budding yeast

(2015) Mark-Albert Saroufim et al.   JOURNAL OF CELL BIOLOGY

Nuclear pore components affect distinct stages of intron-containing gene expression

(2015) Amandine Bonnet et al.   NUCLEIC ACIDS RESEARCH

Inner nuclear envelope protein SUN1 plays a prominent role in mammalian mRNA export

(2015) Ping Li et al.   NUCLEIC ACIDS RESEARCH

The Nuclear PolyA-Binding Protein Nab2p Is Essential for mRNA Production

(2015) Manfred Schmid et al.   Cell Reports

Intron or no intron: a matter for nuclear pore complexes

(2015) Amandine Bonnet et al.   Nucleus

Intron or no intron: a matter for nuclear pore complexes

(2015) Amandine Bonnet et al.   Nucleus

Multiple Export Mechanisms for mRNAs

(2015) Mildred Delaleau et al.   Cells

The multifunctional nuclear pore complex: a platform for controlling gene expression

(2014) Christopher Ptak et al.   CURRENT OPINION IN CELL BIOLOGY

An agent-based model for mRNA export through the nuclear pore complex

(2014) Mohammad Azimi et al.   MOLECULAR BIOLOGY OF THE CELL

Transcriptome Maps of mRNP Biogenesis Factors Define Pre-mRNA Recognition

(2014) Carlo Baejen et al.   MOLECULAR CELL

Sumoylation of the THO complex regulates the biogenesis of a subset of mRNPs

(2014) Hugo Bretes et al.   NUCLEIC ACIDS RESEARCH

Quality control of mRNP biogenesis: Networking at the transcription site

(2014) Andrea B. Eberle et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Quality control of spliced mRNAs requires the shuttling SR proteins Gbp2 and Hrb1

(2014) Alexandra Hackmann et al.   Nature Communications

Regulation of mRNA Trafficking by Nuclear Pore Complexes

(2014) Amandine Bonnet et al.   Genes

RNA quality control in the nucleus: The Angels' share of RNA

(2013) Odil Porrua et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

RNA decay machines: The exosome

(2013) Aleksander Chlebowski et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

A Transcriptome-wide Atlas of RNP Composition Reveals Diverse Classes of mRNAs and lncRNAs

(2013) Alex Charles Tuck et al.   CELL

The human TREX-2 complex is stably associated with the nuclear pore basket

(2013) D. Umlauf et al.   JOURNAL OF CELL SCIENCE

The nuclear basket proteins Mlp1p and Mlp2p are part of a dynamic interactome including Esc1p and the proteasome

(2013) Mario Niepel et al.   MOLECULAR BIOLOGY OF THE CELL

Higher Nucleoporin-Importinβ Affinity at the Nuclear Basket Increases Nucleocytoplasmic Import

(2013) Mohammad Azimi et al.   PLoS One

High-resolution three-dimensional mapping of mRNA export through the nuclear pore

(2013) Jiong Ma et al.   Nature Communications

The Cellular EJC Interactome Reveals Higher-Order mRNP Structure and an EJC-SR Protein Nexus

(2012) Guramrit Singh et al.   CELL

Localization of Nucleoporin Tpr to the Nuclear Pore Complex Is Essential for Tpr Mediated Regulation of the Export of Unspliced RNA

(2012) Kalpana Rajanala et al.   PLoS One

Nuclear export of single native mRNA molecules observed by light sheet fluorescence microscopy

(2012) J. P. Siebrasse et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mRNA export and the TREX complex

(2011) Jun Katahira   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Interaction Profiling Identifies the Human Nuclear Exosome Targeting Complex

(2011) Michal Lubas et al.   MOLECULAR CELL

Nuclear export dynamics of RNA–protein complexes

(2011) David Grünwald et al.   NATURE

Keeping mRNPs in check during assembly and nuclear export

(2011) Evelina Tutucci et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Accounting for Diffusion in Agent Based Models of Reaction-Diffusion Systems with Application to Cytoskeletal Diffusion

(2011) Mohammad Azimi et al.   PLoS One

The Tpr protein regulates export of mRNAs with retained introns that traffic through the Nxf1 pathway

(2011) J. H. Coyle et al.   RNA

Ubiquitin-mediated mRNP dynamics and surveillance prior to budding yeast mRNA export

(2010) N. Iglesias et al.   GENES & DEVELOPMENT

In vivo imaging of labelled endogenous β-actin mRNA during nucleocytoplasmic transport

(2010) David Grünwald et al.   NATURE

Dynamics of single mRNP nucleocytoplasmic transport and export through the nuclear pore in living cells

(2010) Amir Mor et al.   NATURE CELL BIOLOGY

Mechanisms of nuclear mRNA quality control

(2010) Milo B. Fasken et al.   RNA Biology

UIF, a New mRNA Export Adaptor that Works Together with REF/ALY, Requires FACT for Recruitment to mRNA

(2009) Guillaume M. Hautbergue et al.   CURRENT BIOLOGY

Functional Significance of the Interaction between the mRNA-binding Protein, Nab2, and the Nuclear Pore-associated Protein, Mlp1, in mRNA Export

(2008) Milo B. Fasken et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Akt phosphorylation and nuclear phosphoinositide association mediate mRNA export and cell proliferation activities by ALY

(2008) M. Okada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA-binding proteins in human genetic disease

(2008) Kiven E. Lukong et al.   TRENDS IN GENETICS