Modulation of VEGF-A Alternative Splicing as a Novel Treatment in Chronic Kidney Disease

VEGF-A165 b protects against proteinuria in a mouse model with progressive depletion of all endogenous VEGF-A splice isoforms from the kidney

(2017) Megan Stevens et al.   JOURNAL OF PHYSIOLOGY-LONDON

Protective effect of vascular endothelial growth factor against cardiopulmonary bypass‑associated acute kidney injury in beagles

(2017) Yiping Bai et al.   Experimental and Therapeutic Medicine

Therapeutic angiogenesis by vascular endothelial growth factor supplementation for treatment of renal disease

(2016) Omar C. Logue et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Alternative mRNA transcription, processing, and translation: insights from RNA sequencing

(2015) Eleonora de Klerk et al.   TRENDS IN GENETICS

Vascular Endothelial Growth Factor-A165b Is Protective and Restores Endothelial Glycocalyx in Diabetic Nephropathy

(2014) S. Oltean et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Integrative Biology Identifies Shared Transcriptional Networks in CKD

(2014) S. Martini et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Context-dependent control of alternative splicing by RNA-binding proteins

(2014) Xiang-Dong Fu et al.   NATURE REVIEWS GENETICS

Alternative splicing in cancer: implications for biology and therapy

(2014) J Chen et al.   ONCOGENE

Serine–arginine protein kinase 1 (SRPK1) inhibition as a potential novel targeted therapeutic strategy in prostate cancer

(2014) A Mavrou et al.   ONCOGENE

The alternative splicing side of cancer

(2014) Giuseppe Biamonti et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Regulation of splicing by SR proteins and SR protein-specific kinases

(2013) Zhihong Zhou et al.   CHROMOSOMA

Hallmarks of alternative splicing in cancer

(2013) S Oltean et al.   ONCOGENE

The role of VEGF165b in pathophysiology

(2013) Maria Peiris-Pagès   Cell Adhesion & Migration

The Evolutionary Landscape of Alternative Splicing in Vertebrate Species

(2012) N. L. Barbosa-Morais et al.   SCIENCE

WT1 Mutants Reveal SRPK1 to Be a Downstream Angiogenesis Target by Altering VEGF Splicing

(2011) Elianna M. Amin et al.   CANCER CELL

Induction of Podocyte VEGF164 Overexpression at Different Stages of Development Causes Congenital Nephrosis or Steroid-Resistant Nephrotic Syndrome

(2010) Delma Veron et al.   AMERICAN JOURNAL OF PATHOLOGY

Functional diversity of the hnRNPs: past, present and perspectives

(2010) Siew Ping Han et al.   BIOCHEMICAL JOURNAL

Overexpression of VEGF165b in Podocytes Reduces Glomerular Permeability

(2010) Y. Qiu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Overexpression of VEGF-A in podocytes of adult mice causes glomerular disease

(2010) Delma Veron et al.   KIDNEY INTERNATIONAL

Spliceosome Structure and Function

(2010) C. L. Will et al.   Cold Spring Harbor Perspectives in Biology

Vascular Endothelial Growth Factor (VEGF)-A165b Is a Weak In vitro Agonist for VEGF Receptor-2 Due to Lack of Coreceptor Binding and Deficient Regulation of Kinase Activity

(2008) H. Kawamura et al.   CANCER RESEARCH

Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors

(2008) D. G. Nowak et al.   JOURNAL OF CELL SCIENCE

Alternative isoform regulation in human tissue transcriptomes

(2008) Eric T. Wang et al.   NATURE

Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

(2008) Qun Pan et al.   NATURE GENETICS

The Alternatively Spliced Anti-Angiogenic Family of VEGF Isoforms VEGFxxxb in Human Kidney Development

(2008) Heather S. Bevan et al.   NEPHRON PHYSIOLOGY

VEGF Inhibition and Renal Thrombotic Microangiopathy

(2008) Vera Eremina et al.   NEW ENGLAND JOURNAL OF MEDICINE