Sarcolipin Makes Heat, but Is It Adaptive Thermogenesis?

Both brown adipose tissue and skeletal muscle thermogenesis processes are activated during mild to severe cold adaptation in mice

(2017) Naresh C. Bal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inactivation of thermogenic UCP1 as a historical contingency in multiple placental mammal clades

(2017) Michael J. Gaudry et al.   Science Advances

Sarcolipin Promotes Uncoupling of the SERCA Ca2+ Pump by Inducing a Structural Rearrangement in the Energy-Transduction Domain

(2016) Joseph M. Autry et al.   BIOCHEMISTRY

The effects of sarcolipin over-expression in mouse skeletal muscle on metabolic activity

(2015) John Butler et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Sarcolipin Is a Key Determinant of the Basal Metabolic Rate, and Its Overexpression Enhances Energy Expenditure and Resistance against Diet-induced Obesity

(2015) Santosh K. Maurya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Uncoupling Protein 1 and Sarcolipin Are Required to Maintain Optimal Thermogenesis, and Loss of Both Systems Compromises Survival of Mice under Cold Stress

(2015) Leslie A. Rowland et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The N Terminus of Sarcolipin Plays an Important Role in Uncoupling Sarco-endoplasmic Reticulum Ca2+-ATPase (SERCA) ATP Hydrolysis from Ca2+Transport

(2015) Sanjaya K. Sahoo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cold adaptation overrides developmental regulation of sarcolipin expression in mice skeletal muscle: SOS for muscle-based thermogenesis?

(2015) M. Pant et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

S-Palmitoylation andS-Oleoylation of Rabbit and Pig Sarcolipin

(2014) Cédric Montigny et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ablation of sarcolipin decreases the energy requirements for Ca2+transport by sarco(endo)plasmic reticulum Ca2+-ATPases in resting skeletal muscle

(2013) Eric Bombardier et al.   FEBS LETTERS

Sarco(endo)plasmic Reticulum Calcium ATPase (SERCA) Inhibition by Sarcolipin Is Encoded in Its Luminal Tail

(2013) Przemek A. Gorski et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sarcolipin Protein Interaction with Sarco(endo)plasmic Reticulum Ca2+ATPase (SERCA) Is Distinct from Phospholamban Protein, and Only Sarcolipin Can Promote Uncoupling of the SERCA Pump

(2013) Sanjaya K. Sahoo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ca2+/H+ exchange, lumenal Ca2+ release and Ca2+/ATP coupling ratios in the sarcoplasmic reticulum ATPase

(2013) Giuseppe Inesi et al.   Journal of Cell Communication and Signaling

Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals

(2012) Naresh C Bal et al.   NATURE MEDICINE

Threonine-5 at the N-terminus can modulate sarcolipin function in cardiac myocytes

(2009) Poornima Bhupathy et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY