Atherosclerosis Is an Inflammatory Disease which Lacks a Common Anti-inflammatory Therapy: How Human Genetics Can Help to This Issue. A Narrative Review

Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms

(2017) Joanna M M Howson et al.   NATURE GENETICS

Targeting Inflammation in Coronary Artery Disease

(2017) Robert A. Harrington   NEW ENGLAND JOURNAL OF MEDICINE

Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease

(2017) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Variants in ANRIL gene correlated with its expression contribute to myocardial infarction risk

(2017) Jie Cheng et al.   Oncotarget

Sex-specific association of SH2B3 and SMARCA4 polymorphisms with coronary artery disease susceptibility

(2017) Yuqiang Ji et al.   Oncotarget

Variants in the CXCL12 gene was associated with coronary artery disease susceptibility in Chinese Han population

(2017) Junbo Zhang et al.   Oncotarget

Genetics of Coronary Artery Disease in Taiwan: A Cardiometabochip Study by the Taichi Consortium

(2016) Themistocles L. Assimes et al.   PLoS One

The effects of tumour necrosis factor inhibitors, methotrexate, non-steroidal anti-inflammatory drugs and corticosteroids on cardiovascular events in rheumatoid arthritis, psoriasis and psoriatic arthritis: a systematic review and meta-analysis

(2015) Camille Roubille et al.   ANNALS OF THE RHEUMATIC DISEASES

Novel 6p21.3 Risk Haplotype Predisposes to Acute Coronary SyndromeCLINICAL PERSPECTIVE

(2015) Juha Sinisalo et al.   Circulation-Cardiovascular Genetics

Significance of eosinophil accumulation in the thrombus and decrease in peripheral blood in patients with acute coronary syndrome

(2015) Ping Jiang et al.   CORONARY ARTERY DISEASE

Novel 6p21.3 Risk Haplotype Predisposes to Acute Coronary SyndromeCLINICAL PERSPECTIVE

(2015) Juha Sinisalo et al.   Circulation-Cardiovascular Genetics

The effect of interleukin-1 receptor antagonist therapy on markers of inflammation in non-ST elevation acute coronary syndromes: the MRC-ILA Heart Study

(2014) A. C. Morton et al.   EUROPEAN HEART JOURNAL

Anti-inflammatory therapies for cardiovascular disease

(2014) P. M. Ridker et al.   EUROPEAN HEART JOURNAL

Effect of Darapladib on Major Coronary Events After an Acute Coronary Syndrome

(2014) Michelle L. O’Donoghue et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Varespladib and Cardiovascular Events in Patients With an Acute Coronary Syndrome

(2014) Stephen J. Nicholls et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Darapladib for Preventing Ischemic Events in Stable Coronary Heart Disease

(2014)   NEW ENGLAND JOURNAL OF MEDICINE

Rationale and design of the Cardiovascular Inflammation Reduction Trial: A test of the inflammatory hypothesis of atherothrombosis

(2013) Brendan M. Everett et al.   AMERICAN HEART JOURNAL

Overlap Between Common Genetic Polymorphisms Underpinning Kidney Traits and Cardiovascular Disease Phenotypes: The CKDGen Consortium

(2013) Matthias Olden et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Rationale and Design of the TETHYS Trial: The Effects of Methotrexate Therapy on Myocardial Infarction with ST-Segment Elevation

(2013) Daniel Medeiros Moreira et al.   CARDIOLOGY

Identification of CAD candidate genes in GWAS loci and their expression in vascular cells

(2013) Ayca Erbilgin et al.   JOURNAL OF LIPID RESEARCH

Secretory Phospholipase A 2 -IIA and Cardiovascular Disease

(2013) Michael V. Holmes et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials

(2013)   LANCET

Inflammation in Atherosclerosis

(2012) Peter Libby   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A Genome-Wide Association Study for Coronary Artery Disease Identifies a Novel Susceptibility Locus in the Major Histocompatibility Complex

(2012) Robert W. Davies et al.   Circulation-Cardiovascular Genetics

Re-evaluation of the risk for major adverse cardiovascular events in patients treated with anti-IL-12/23 biological agents for chronic plaque psoriasis: a meta-analysis of randomized controlled trials

(2012) T. Tzellos et al.   JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY

Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies

(2012)   LANCET

A novel major histocompatibility complex locus confers the risk of premature coronary artery disease in a Chinese Han population

(2012) Fangyi Xie et al.   MOLECULAR BIOLOGY REPORTS

Large-scale association analysis identifies new risk loci for coronary artery disease

(2012) Panos Deloukas et al.   NATURE GENETICS

Systematic Review and Meta-Analysis of Methotrexate Use and Risk of Cardiovascular Disease

(2011) Renata Micha et al.   AMERICAN JOURNAL OF CARDIOLOGY

Treatment with tumor necrosis factor inhibitors and the risk of acute coronary syndromes in early rheumatoid arthritis

(2011) Lotta Ljung et al.   ARTHRITIS AND RHEUMATISM

The novel atherosclerosis locus at 10q11 regulates plasma CXCL12 levels

(2011) Nehal N. Mehta et al.   EUROPEAN HEART JOURNAL

Adaptor protein Lnk binds to PDGF receptor and inhibits PDGF-dependent signaling

(2011) Saskia Gueller et al.   EXPERIMENTAL HEMATOLOGY

Association Between Biologic Therapies for Chronic Plaque Psoriasis and Cardiovascular Events

(2011) Caitriona Ryan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Relative contribution of PECAM-1 adhesion and signaling to the maintenance of vascular integrity

(2011) J. R. Privratsky et al.   JOURNAL OF CELL SCIENCE

Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wide association studies

(2011) Muredach P Reilly et al.   LANCET

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

(2011) Georg B. Ehret et al.   NATURE

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

(2011) Heribert Schunkert et al.   NATURE GENETICS

Replication of Putative Susceptibility Loci from Genome-Wide Association Studies Associated with Coronary Atherosclerosis in Chinese Han Population

(2011) Fang Xie et al.   PLoS One

Inhibition of Lipoprotein-Associated Phospholipase A2 Ameliorates Inflammation and Decreases Atherosclerotic Plaque Formation in ApoE-Deficient Mice

(2011) Wen-yi Wang et al.   PLoS One

Large Scale Association Analysis Identifies Three Susceptibility Loci for Coronary Artery Disease

(2011) Stephanie Saade et al.   PLoS One

CXCL12: A New Player in Coronary Disease Identified through Human Genetics

(2011) Samira S. Farouk et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Large-Scale Gene-Centric Analysis Identifies Novel Variants for Coronary Artery Disease

(2011)   PLoS Genetics

ANRIL Expression Is Associated With Atherosclerosis Risk at Chromosome 9p21

(2010) Lesca M. Holdt et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Expression of Chr9p21 genes CDKN2B (p15INK4b), CDKN2A (p16INK4a, p14ARF) and MTAP in human atherosclerotic plaque

(2010) Lesca Miriam Holdt et al.   ATHEROSCLEROSIS

Effects of Varespladib Methyl on Biomarkers and Major Cardiovascular Events in Acute Coronary Syndrome Patients

(2010) Robert S. Rosenson et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Tumour necrosis factor antagonists and the risk of cardiovascular disease in patients with rheumatoid arthritis: a systematic literature review

(2010) S. L. Westlake et al.   RHEUMATOLOGY

Systematic review and meta-analysis: Anti-tumor necrosis factor α therapy and cardiovascular events in rheumatoid arthritis

(2010) Cheryl Barnabe et al.   ARTHRITIS CARE & RESEARCH

Large Scale Association Analysis of Novel Genetic Loci for Coronary Artery Disease

(2009)   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction

(2009) Daniel F Gudbjartsson et al.   NATURE GENETICS

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

(2009) Sekar Kathiresan et al.   NATURE GENETICS

How much is too much? Interleukin-6 and its signalling in atherosclerosis

(2009) Harald Schuett et al.   THROMBOSIS AND HAEMOSTASIS

Repeated Replication and a Prospective Meta-Analysis of the Association Between Chromosome 9p21.3 and Coronary Artery Disease

(2008) Heribert Schunkert et al.   CIRCULATION

Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive Protein

(2008) Paul M Ridker et al.   NEW ENGLAND JOURNAL OF MEDICINE