Astragaloside IV Inhibits Triglyceride Accumulation in Insulin-Resistant HepG2 Cells via AMPK-Induced SREBP-1c Phosphorylation

Research review on the pharmacological effects of astragaloside IV

(2016) Lei Li et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Astragaloside IV facilitates glucose transport in C2C12 myotubes through the IRS1/AKT pathway and suppresses the palmitate-induced activation of the IKK/IκBα pathway

(2016) RONGFENG ZHU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

The multiple-hit pathogenesis of non-alcoholic fatty liver disease (NAFLD)

(2016) Elena Buzzetti et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Astragaloside IV improves lipid metabolism in obese mice by alleviation of leptin resistance and regulation of thermogenic network

(2016) Hui Wu et al.   Scientific Reports

AMPK: positive and negative regulation, and its role in whole-body energy homeostasis

(2015) D Grahame Hardie   CURRENT OPINION IN CELL BIOLOGY

Astragaloside IV and cycloastragenol are equally effective in inhibition of endoplasmic reticulum stress-associated TXNIP/NLRP3 inflammasome activation in the endothelium

(2015) Yan Zhao et al.   JOURNAL OF ETHNOPHARMACOLOGY

The protective effect of astragaloside IV against benzo[a]pyrene induced endothelial progenitor cell dysfunction

(2015) Kangting Ji et al.   LIFE SCIENCES

Astragaloside IV Inhibits NF-κB Activation and Inflammatory Gene Expression in LPS-Treated Mice

(2015) Wei-Jian Zhang et al.   MEDIATORS OF INFLAMMATION

Free radical biology for medicine: learning from nonalcoholic fatty liver disease

(2013) Gaetano Serviddio et al.   FREE RADICAL BIOLOGY AND MEDICINE

Non Alcoholic Fatty Liver Disease in Southern Iran: A Population Based Study

(2013) Kamran Bagheri Lankarani et al.   Hepatitis Monthly

Epidemiology of alcoholic and nonalcoholic fatty liver disease in China

(2013) Jian-Gao Fan   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

Anti-Inflammatory Cycloartane-Type Saponins of Astragalus membranaceus

(2013) Dae-Young Lee et al.   MOLECULES

Regulation of energy metabolism by long-chain fatty acids

(2013) Manabu T. Nakamura et al.   PROGRESS IN LIPID RESEARCH

AMP-activated protein kinase: new regulation, new roles?

(2012) David Carling et al.   BIOCHEMICAL JOURNAL

Astragaloside IV Downregulates β-Catenin in Rat Keratinocytes to Counter LiCl-Induced Inhibition of Proliferation and Migration

(2012) Fu-Lun Li et al.   Evidence-based Complementary and Alternative Medicine

Association between diabetes, family history of diabetes, and risk of nonalcoholic steatohepatitis and fibrosis

(2012) Rohit Loomba et al.   HEPATOLOGY

AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice

(2011) Yu Li et al.   Cell Metabolism

AMP-activated protein kinase mediates erythropoietin-induced activation of endothelial nitric oxide synthase

(2011) Kuo-Hui Su et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The healing and anti-scar effects of astragaloside IV on the wound repair in vitro and in vivo

(2011) Xi Chen et al.   JOURNAL OF ETHNOPHARMACOLOGY

Astragaloside IV Stimulates Angiogenesis and Increases Hypoxia-Inducible Factor-1  Accumulation via Phosphatidylinositol 3-Kinase/Akt Pathway

(2011) L. Zhang et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease

(2011) N. Kumashiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overexpression of AMPKα1 Ameliorates Fatty Liver in Hyperlipidemic Diabetic Rats

(2010) Eunhui Seo et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

A Crystallized View of AMPK Activation

(2009) Lawrence H. Young   Cell Metabolism

Astragaloside IV attenuates lipolysis and improves insulin resistance induced by TNFαin 3T3-L1 adipocytes

(2008) Boren Jiang et al.   PHYTOTHERAPY RESEARCH

Astragaloside IV Inhibits Proliferation and Promotes Apoptosis in Rat Vascular Smooth Muscle Cells under High Glucose Concentrationin vitro

(2008) Wei Yuan et al.   PLANTA MEDICA