Article
Immunology
Johnna R. Swartz, Angelica F. Carranza, Laura M. Tully, Annchen R. Knodt, Janina Jiang, Michael R. Irwin, Camelia E. Hostinar
Summary: The study found associations between peripheral inflammation and adolescent brain connectivity, with higher TNF-α levels linked to changes in neural network connections. Associations with IL-6 and CRP were not significant, suggesting that inflammation may have unique effects on brain connectivity during adolescence.
BRAIN BEHAVIOR AND IMMUNITY
(2021)
Article
Neurosciences
Limin Peng, Zhiguo Luo, Ling-Li Zeng, Chenping Hou, Hui Shen, Zongtan Zhou, Dewen Hu
Summary: This study developed a brain parcellation method based on dynamic functional connectivity and created a new functional brain atlas. The atlas can reveal finer functional boundaries that static methods may overlook, and shows good agreement with cytoarchitectonic areas and task activation maps.
Article
Computer Science, Artificial Intelligence
Mingliang Wang, Jiashuang Huang, Mingxia Liu, Daoqiang Zhang
Summary: This study proposes a temporal dynamics learning (TDL) method for network-based brain disease identification using rs-fMRI time-series data. By integrating network feature extraction and classifier training into a unified framework, it addresses the issues of previous studies paying less attention to the evolution of global network structures over time and treating feature extraction and training as separate tasks.
MEDICAL IMAGE ANALYSIS
(2021)
Article
Neurosciences
Jung-Hoon Kim, Josepheen De Asis-Cruz, Kushal Kapse, Catherine Limperopoulos
Summary: The reliability and robustness of rs-fcMRI depend on minimizing the influence of head motion on brain signals. This study examined the impact of head motion on newborn brain connectivity using a large dataset. The findings revealed that head motion significantly affected connectivity, with specific effects observed in sensory-related and default mode networks. Implementing a motion correction strategy helped reduce the confounding effects of head motion on neonatal rs-fcMRI.
HUMAN BRAIN MAPPING
(2023)
Article
Neurosciences
Luoyao Pang, Huidi Li, Quanying Liu, Yue-Jia Luo, Dean Mobbs, Haiyan Wu
Summary: Motivated dishonesty is a common social behavior that varies among individuals. This study explores the relationship between brain networks and dishonesty using resting-state functional magnetic resonance imaging (rsfMRI), and demonstrates the ability to predict dishonest behavior through a model based on functional connectivity.
Article
Neurosciences
Yongfa Zhang, Fei Wang, Jie Sui
Summary: Recent research supports a fundamental self hypothesis, suggesting that the self is a baseline function of the brain that regulates cognitive processing and behavior. Understanding this hypothesis can help identify the emergence of self-biased behaviors and predict the influence of brain signals at rest on such behaviors.
Article
Neurosciences
Jeffrey M. Kenzie, Deepthi Rajashekar, Bradley G. Goodyear, Sean P. Dukelow
Summary: Around 50% of stroke patients have deficits in proprioception, but our understanding of the neurological mechanisms behind these deficits is limited. This study used resting-state functional magnetic resonance imaging (fMRI) to investigate changes in functional brain networks associated with proprioception deficits in stroke patients. The results showed reduced connectivity in specific brain regions, including the supplementary motor area and the supramarginal gyrus, in stroke patients compared to healthy controls. Functional connectivity of these regions, as well as the primary somatosensory cortex and the parietal opercular area, was significantly associated with proprioceptive function. The parietal lobe of the lesioned hemisphere was identified as an important node for proprioception after stroke, and evaluating the functional connectivity of this region could help predict recovery. The study also identified potential targets for therapeutic neurostimulation to aid in stroke recovery.
HUMAN BRAIN MAPPING
(2023)
Article
Neurosciences
Shachar Gal, Yael Coldham, Niv Tik, Michal Bernstein-Eliav, Ido Tavor
Summary: The search for an ideal approach to investigate functional connections in the human brain is a challenge for neuroscience. Recent studies have found that using naturalistic stimuli to collect functional connectivity data predicts cognitive and emotional scores more accurately than using resting-state data. Furthermore, activation maps predicted using naturalistic stimuli are better predictors of individual intelligence scores than those predicted using resting-state data.
Article
Neurosciences
Andria J. Farrens, Shahabeddin Vahdat, Fabrizio Sergi
Summary: Dynamic adaptation is the process of adjusting motor actions to changes in task dynamics. Adapted motor plans are consolidated into memories that contribute to better performance on re-exposure. This study used functional magnetic resonance imaging (fMRI) to investigate resting state functional connectivity (rsFC) specific to dynamic adaptation of wrist movements and subsequent memory formation.
JOURNAL OF NEUROSCIENCE
(2023)
Article
Multidisciplinary Sciences
Won Beom Jung, Haiyan Jiang, Soohyun Lee, Seong-Gi Kim
Summary: In order to advance fMRI-based brain science, it is important to analyze fMRI activity at the circuit level. This study combines whole-brain fMRI with neuronal silencing to dissect the responses and circuits of the somatosensory network.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Psychology, Clinical
Cope Feurer, Jagan Jimmy, Fini Chang, Scott A. Langenecker, K. Luan Phan, Olusola Ajilore, Heide Klumpp
Summary: This study explored the relationship between brain activity and rumination and worry in internalizing conditions. The results indicate the involvement of the affective network in rumination and worry, as well as distinct connectivity patterns observed in patients with internalizing conditions. The findings suggest different mechanisms contribute to rumination as a unitary construct and worry as a unique construct.
DEPRESSION AND ANXIETY
(2021)
Article
Psychology, Clinical
Lizhu Luo, Christelle Langley, Laura Moreno-Lopez, Keith Kendrick, David K. Menon, Emmanuel A. Stamatakis, Barbara J. Sahakian
Summary: This study examined the association between depressive symptoms in traumatic brain injury (TBI) patients and altered resting-state functional connectivity (rs-fc) or voxel-based morphology in brain regions involved in emotional regulation and associated with depression. The results showed a positive association between depression scores and rs-fc between limbic regions and cognitive control regions, while there was a negative association between depression scores and rs-fc between limbic and frontal regions involved in emotion regulation. These findings contribute to a better understanding of the mechanisms underlying depression following TBI and can inform treatment decisions.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Neurosciences
Marie-Stephanie Cahart, Owen O'Daly, Vincent Giampietro, Maarten Timmers, Johannes Streffer, Steven Einstein, Fernando Zelaya, Flavio Dell'Acqua, Steven C. R. Williams
Summary: This study compared the reliability of conventional single-band fMRI and different multiband (MB) fMRI acquisitions with and without in-plane acceleration across multiple scanning sessions. It found that for cortical areas, MB factor 4 without in-plane acceleration had the highest reliability, while for subcortical areas, conventional single-band fMRI was more reliable.
HUMAN BRAIN MAPPING
(2023)
Article
Neurosciences
Serafeim Loukas, Lara Lordier, Djalel-Eddine Meskaldji, Manuela Filippa, Joana Sa de Almeida, Dimitri Van de Ville, Petra S. Hueppi
Summary: Research indicates that even during the newborn period, familiar music and unfamiliar music are processed differently by the brain. After music listening, functional connectivity between brain regions in all newborns is modulated. Premature infants exposed to music experience enhanced functional connectivity between brain regions after listening to music.
HUMAN BRAIN MAPPING
(2022)
Article
Neurosciences
John Thomas, Dixit Sharma, Sounak Mohanta, Neeraj Jain
Summary: Information processing in the brain is mediated through a complex functional network architecture, with different nodes integrating and segregating themselves on various timescales. Our study identified distinct networks in the somatosensory area 3b, showing different correlation patterns among face, hand, and medial representations in macaque monkeys and humans. The results suggest that different body part representations in area 3b have independent functional networks, reflecting differences in the behavioral use of those body parts.
Article
Otorhinolaryngology
Zigang Che, Qingxiang Zhang, Pengfei Zhao, Han Lv, Heyu Ding, Jing Li, Hao Wang, Peng Zhang, Hongbo Ji, Caiyun Zou, Zhenchang Wang
Summary: This study observed bony changes in chronic maxillary sinusitis (CMS) using CT and proposed a method for evaluating CMS with osteitis. The results showed that bone changes can occur in the maxillary sinus walls and spread to adjacent bones, with both increased and decreased density.
ENT-EAR NOSE & THROAT JOURNAL
(2023)
Editorial Material
Medicine, General & Internal
Han Lv, Mengyi Li, Zhenchang Wang, Dawei Yang, Hui Xu, Juan Li, Yang Liu, Di Cao, Yawen Liu, Xinru Wu, He Jin, Peng Zhang, Liqin Zhao, Rixing Bai, Yunlong Yue, Bin Li, Nengwei Zhang, Mingzhu Zou, Jinghai Song, Weibin Yu, Pin Zhang, Weijun Tang, Qiyuan Yao, Liheng Liu, Hui Yang, Zhenghan Yang, Zhongtao Zhang
CHINESE MEDICAL JOURNAL
(2022)
Article
Computer Science, Interdisciplinary Applications
Li Liu, Zhenxia Mu, Yizhou Kang, Suqin Huang, Xiaoyu Qiu, Xiaofei Xue, Minrui Fu, Qingxin Xue, Han Lv, Bin Gao, Shu Li, Pengfei Zhao, Heyu Ding, Zhenchang Wang
Summary: This study combined the finite element method and computational fluid dynamics to explore the hemodynamic mechanism of coil embolization in the treatment of sigmoid sinus diverticulum. The results showed that coil embolization reduced the average velocity, wall pressure, and wall shear stress of the sigmoid sinus, while increasing the proportion of low-velocity region in the cortical plate dehiscence area.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xiaoshuai Li, Ning Xu, Xuxu Meng, Chihang Dai, Xiaoyu Qiu, Heyu Ding, Han Lv, Rong Zeng, Jing Xie, Pengfei Zhao, Zhenghan Yang, Shusheng Gong, Zhenchang Wang
Summary: The study aimed to investigate the diagnostic performance of dual-phase contrast-enhanced CT (DP-CECT) for intracranial dural arteriovenous fistula (DAVF) in patients with pulsatile tinnitus (PT), compared with digital subtraction angiography (DSA). The results showed that DP-CECT had high sensitivity and specificity for the diagnosis of DAVF in PT patients.
EUROPEAN JOURNAL OF RADIOLOGY
(2022)
Article
Neurosciences
Qian Chen, Han Lv, Zhaodi Wang, Xuan Wei, Jiao Liu, Fang Liu, Pengfei Zhao, Zhenghan Yang, Shusheng Gong, Zhenchang Wang
Summary: This study found significant brain network topological alterations in tinnitus patients, especially in the structural brain network. Patients with different treatment outcomes showed distinct structural-functional coupling properties. Structural-functional coupling could be used as an indicator to predict the prognosis of patients with idiopathic tinnitus before sound therapy.
HUMAN BRAIN MAPPING
(2022)
Article
Biophysics
Zhenxia Mu, Xiaoshuai Li, Dawei Zhao, Xiaoyu Qiu, Chihang Dai, Xuxu Meng, Suqin Huang, Bin Gao, Han Lv, Shu Li, Pengfei Zhao, Youjun Liu, Zhenchang Wang, Yu Chang
Summary: This study investigated the relationship between the position of sigmoid sinus wall dehiscence (SSWD) and the blood flow pattern at the junction of the transverse sinus and sigmoid sinus (TS-SS). It was found that the location of high-velocity blood flow impacting the vessel wall was consistent with SSWD, and the temporal bone was thinner in healthy volunteers where the blood flow impacted the vessel wall. The study also revealed higher wall shear stress and pressure in the SSWD area. Therefore, the impact of blood flow may be an important pathological mechanism of SSWD.
JOURNAL OF BIOMECHANICS
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Di Cao, Mengyi Li, Yang Liu, He Jin, Dawei Yang, Hui Xu, Han Lv, JIa Liu, Peng Zhang, Zhongtao Zhang, Zhenghan Yang
Summary: This study assessed the effect of different ROI sampling strategies on the measurement of liver fat content. The results showed that the 9L-ROI sampling strategy at the whole-liver level performed best when liver puncture biopsy was not used as the gold standard, while the 3L-ROI sampling strategy at the puncture site segment was recommended when liver puncture biopsy was used as the gold standard.
BMC MEDICAL IMAGING
(2022)
Article
Neurosciences
Peng Zhang, Guo-wei Wu, Li-rong Tang, Feng-xia Yu, Meng-yi Li, Zheng Wang, Zheng-han Yang, Zhong-tao Zhang, Han Lv, Yang Liu, Zhen-chang Wang
Summary: This article investigates the neural mechanisms of food evaluation in the brain of individuals with obesity and explores the correlation between structural changes and eating behavior. The study found that increased gray matter volume in the left parahippocampal gyrus may play a role in obesity-related reward devaluation and altered behavioral inhibition. These findings have important implications for understanding obesity and developing personalized strategies for prevention.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Medical Informatics
Jia Li, Yucong Lin, Pengfei Zhao, Wenjuan Liu, Linkun Cai, Jing Sun, Lei Zhao, Zhenghan Yang, Hong Song, Han Lv, Zhenchang Wang
Summary: This study proposes a reliable BERT-based framework for tinnitus diagnosis from Chinese radiology reports, along with a sequence adaptation strategy to reduce computational resources while maintaining accuracy. The findings demonstrate that the BERT model performs well in tinnitus diagnosis.
BMC MEDICAL INFORMATICS AND DECISION MAKING
(2022)
Article
Biotechnology & Applied Microbiology
Xinghao Wang, Jia Li, Jing Sun, Wenjuan Liu, Linkun Cai, Pengfei Zhao, Zhenghan Yang, Han Lv, Zhenchang Wang
Summary: The purpose of this study was to develop and validate a machine learning model using enhanced MRI to determine the pathological grading of meningiomas. The results showed that multi-habitat analysis based on enhanced MRI accurately predicted the pathological grading of meningiomas. This unsupervised image-based method reflected the direct heterogeneity between high-grade meningiomas and low-grade meningiomas.
BIOMED RESEARCH INTERNATIONAL
(2022)
Article
Engineering, Biomedical
Han Lv, Jinduo Liu, Qian Chen, Zuozhen Zhang, Zhaodi Wang, Shusheng Gong, Junzhong Ji, Zhenchang Wang
Summary: The study reveals abnormal functional connectivity of multiple brain regions in tinnitus patients and suggests that analyzing the direction of functional connectivity can provide key information on treatment outcomes. Resting-state functional magnetic resonance images were acquired and an effective connectivity network was constructed using an artificial bee colony algorithm and transfer entropy. The findings highlight the increased signal output in sensory networks of tinnitus patients, which may explain poor clinical outcomes.
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING
(2023)
Article
Neurosciences
Qian Chen, Han Lv, Zhaodi Wang, Xiaoshuai Li, Xinghao Wang, Yuyou Huang, Pengfei Zhao, Zhenghan Yang, Shusheng Gong, Zhenchang Wang
Summary: This study investigated structural and functional changes in the thalamus and its subregions using multimodal magnetic resonance imaging (MRI) and examined its clinical relevance in tinnitus patients with different treatment outcomes. The results showed that tinnitus patients, regardless of treatment efficacy, exhibited widespread abnormalities in the thalamus and its subregions, with more significant changes in the effective group. A combination of multimodal quantitative thalamic properties can be used as indicators to predict tinnitus prognosis before sound therapy.
CNS NEUROSCIENCE & THERAPEUTICS
(2023)
Article
Urology & Nephrology
Hao Wang, Xu Liu, Lijun Song, Wenbo Yang, Mingan Li, Qian Chen, Han Lv, Pengfei Zhao, Zhenghan Yang, Wenhu Liu, Zhen-chang Wang
Summary: This study used magnetic resonance imaging to investigate cognitive decline in patients with chronic kidney disease (CKD) and found that changes in cerebral blood flow and susceptibility might be related to this decline. The study suggests that magnetic resonance imaging parameters could serve as potential biomarkers for assessing cognitive decline in patients with CKD.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2023)
Article
Oncology
Jia Li, Xinghao Wang, Linkun Cai, Jing Sun, Zhenghan Yang, Wenjuan Liu, Zhenchang Wang, Han Lv
Summary: This study introduces a fusion model that effectively integrates free-text medical record data and structured laboratory data to predict liver metastasis in postoperative colorectal cancer patients. The fusion model demonstrates superior predictive performance and has the potential to enhance patient outcomes and support clinical decision-making.
Article
Clinical Neurology
Qian Chen, Han Lv, Zhaodi Wang, Xiaoshuai Li, Xinghao Wang, Yuyou Huang, Pengfei Zhao, Zhenghan Yang, Shusheng Gong, Zhenchang Wang
Summary: This study aimed to examine the structural and functional changes in the insula and its subregions in patients with tinnitus, and to identify the neural changes involved in the progression from recent onset to chronic tinnitus. The results showed that both recent-onset and chronic tinnitus patients exhibited decreased low-frequency fluctuation in the insula and its subregions. Only chronic tinnitus patients showed bilateral grey matter atrophy in the ventral anterior insula. Abnormal functional connectivity was observed in both recent-onset and chronic tinnitus patients. However, functional connectivity differences between recent-onset and chronic tinnitus patients were only found in the auditory-related cortex, frontal cortex, and limbic system. Functional alterations, but not structural changes, were found to be correlated with clinical severity. These findings suggest that tinnitus generation and development involve dynamic multi-structural and functional reorganization of the insula.
BRAIN COMMUNICATIONS
(2023)
