Hyperactivity and Hypermotivation Associated With Increased Striatal mGluR1 Signaling in a Shank2 Rat Model of Autism

Comprehensive analysis of two Shank3 and the Cacna1c mouse models of autism spectrum disorder

(2017) P.A. Kabitzke et al.   GENES BRAIN AND BEHAVIOR

Striatopallidal dysfunction underlies repetitive behavior in Shank3-deficient model of autism

(2017) Wenting Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

SHANK proteins: roles at the synapse and in autism spectrum disorder

(2017) Patricia Monteiro et al.   NATURE REVIEWS NEUROSCIENCE

Obsessive-compulsive disorder: Insights from animal models

(2017) Henry Szechtman et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Replicable in vivo physiological and behavioral phenotypes of the Shank3B null mutant mouse model of autism

(2017) Sameer C. Dhamne et al.   Molecular Autism

Integrative Analysis of Brain Region-specific Shank3 Interactomes for Understanding the Heterogeneity of Neuronal Pathophysiology Related to SHANK3 Mutations

(2017) Yeunkum Lee et al.   Frontiers in Molecular Neuroscience

Proteomic Analysis of Post-synaptic Density Fractions from Shank3 Mutant Mice Reveals Brain Region Specific Changes Relevant to Autism Spectrum Disorder

(2017) Dominik Reim et al.   Frontiers in Molecular Neuroscience

Novel Shank3 mutant exhibits behaviors with face validity for autism and altered striatal and hippocampal function

(2016) Thomas C. Jaramillo et al.   Autism Research

Neuronal mechanisms and circuits underlying repetitive behaviors in mouse models of autism spectrum disorder

(2016) Hyopil Kim et al.   Behavioral and Brain Functions

Rodent models in neuroscience research: is it a rat race?

(2016) Bart Ellenbroek et al.   Disease Models & Mechanisms

Erratum: Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice

(2016) C Vicidomini et al.   MOLECULAR PSYCHIATRY

Adult restoration of Shank3 expression rescues selective autistic-like phenotypes

(2016) Yuan Mei et al.   NATURE

Early hyperactivity and precocious maturation of corticostriatal circuits in Shank3B−/− mice

(2016) Rui T Peixoto et al.   NATURE NEUROSCIENCE

SHANK3 controls maturation of social reward circuits in the VTA

(2016) Sebastiano Bariselli et al.   NATURE NEUROSCIENCE

Measuring Social Motivation Using Signal Detection and Reward Responsiveness

(2016) Coralie Chevallier et al.   PLoS One

Altered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism

(2016) Xiaoming Wang et al.   Nature Communications

Reduction in parvalbumin expression not loss of the parvalbumin-expressing GABA interneuron subpopulation in genetic parvalbumin and shank mouse models of autism

(2016) Federica Filice et al.   Molecular Brain

Opposite Effects of mGluR1a and mGluR5 Activation on Nucleus Accumbens Medium Spiny Neuron Dendritic Spine Density

(2016) Kellie S. Gross et al.   PLoS One

Altered Striatal Synaptic Function and Abnormal Behaviour inShank3Exon4-9 Deletion Mouse Model of Autism

(2015) Thomas C. Jaramillo et al.   Autism Research

Altered white matter connectivity as a neural substrate for social impairment in Autism Spectrum Disorder

(2015) Stephanie H. Ameis et al.   CORTEX

Electrophysiological biomarkers of diagnosis and outcome in neurodevelopmental disorders

(2015) Shafali S. Jeste et al.   CURRENT OPINION IN NEUROLOGY

Autism-Associated Insertion Mutation (InsG) of Shank3 Exon 21 Causes Impaired Synaptic Transmission and Behavioral Deficits

(2015) H. E. Speed et al.   JOURNAL OF NEUROSCIENCE

Modeling psychiatric disorders for developing effective treatments

(2015) Tobias Kaiser et al.   NATURE MEDICINE

Striatal Development in Autism: Repetitive Behaviors and the Reward Circuitry

(2014) Gregor Kohls et al.   BIOLOGICAL PSYCHIATRY

In-depth protein profiling of the postsynaptic density from mouse hippocampus using data-independent acquisition proteomics

(2014) Ute Distler et al.   PROTEOMICS

Loss of Predominant Shank3 Isoforms Results in Hippocampus-Dependent Impairments in Behavior and Synaptic Transmission

(2013) M. Kouser et al.   JOURNAL OF NEUROSCIENCE

SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties

(2013) Kihoon Han et al.   NATURE

Dorsal and ventral streams: The distinct role of striatal subregions in the acquisition and performance of goal-directed actions

(2013) Genevra Hart et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Modeling Autism by SHANK Gene Mutations in Mice

(2013) Yong-hui Jiang et al.   NEURON

Time-dependent decreases in nucleus accumbens AMPA/NMDA ratio and incubation of sucrose craving in adolescent and adult rats

(2013) Danielle S. Counotte et al.   PSYCHOPHARMACOLOGY

Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2

(2012) Michael J. Schmeisser et al.   NATURE

Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function

(2012) Hyejung Won et al.   NATURE

Synaptic and Behavioral Profile of Multiple Glutamatergic Inputs to the Nucleus Accumbens

(2012) Jonathan P. Britt et al.   NEURON

The social motivation theory of autism

(2012) Coralie Chevallier et al.   TRENDS IN COGNITIVE SCIENCES

Genetic and Functional Analyses of SHANK2 Mutations Suggest a Multiple Hit Model of Autism Spectrum Disorders

(2012) Claire S. Leblond et al.   PLoS Genetics

Inherited and de novo SHANK2 variants associated with autism spectrum disorder impair neuronal morphogenesis and physiology

(2011) Simone Berkel et al.   HUMAN MOLECULAR GENETICS

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

(2011) João Peça et al.   NATURE

Mutations in the SHANK2 synaptic scaffolding gene in autism spectrum disorder and mental retardation

(2010) Simone Berkel et al.   NATURE GENETICS

Group 1 mGluR-Dependent Synaptic Long-Term Depression: Mechanisms and Implications for Circuitry and Disease

(2010) Christian Lüscher et al.   NEURON

D1 and D2 dopamine receptors differentially mediate the activation of phosphoproteins in the striatum of amphetamine-sensitized rats

(2010) Xiangdang Shi et al.   PSYCHOPHARMACOLOGY

Maternal separation enhances offensive play-fighting, basal corticosterone and hypothalamic vasopressin mRNA expression in juvenile male rats

(2008) Alexa H. Veenema et al.   PSYCHONEUROENDOCRINOLOGY