Different Expression Levels of Human Mutant Ubiquitin B+1 (UBB+1) Can Modify Chronological Lifespan or Stress Resistance of Saccharomyces cerevisiae

Interplay of Energetics and ER Stress Exacerbates Alzheimer's Amyloid-β (Aβ) Toxicity in Yeast

(2017) Xin Chen et al.   Frontiers in Molecular Neuroscience

Accumulation of Basic Amino Acids at Mitochondria Dictates the Cytotoxicity of Aberrant Ubiquitin

(2015) Ralf J. Braun et al.   Cell Reports

Extended ubiquitin species are protein-based DUB inhibitors

(2014) Daria Krutauz et al.   Nature Chemical Biology

Identification and Rescue of  -Synuclein Toxicity in Parkinson Patient-Derived Neurons

(2013) C. Y. Chung et al.   SCIENCE

Yeast Reveal a "Druggable" Rsp5/Nedd4 Network that Ameliorates  -Synuclein Toxicity in Neurons

(2013) D. F. Tardiff et al.   SCIENCE

Mutant ubiquitin (UBB+1) associated with neurodegenerative disorders is hydrolyzed by ubiquitin C-terminal hydrolase L3 (UCH-L3)

(2011) Frank J.A. Dennissen et al.   FEBS LETTERS

Structural Basis of E2–25K/UBB+1Interaction Leading to Proteasome Inhibition and Neurotoxicity

(2010) Sunggeon Ko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modelling neurodegeneration in Saccharomyces cerevisiae: why cook with baker's yeast?

(2010) Vikram Khurana et al.   NATURE REVIEWS NEUROSCIENCE

Modest proteasomal inhibition by aberrant ubiquitin exacerbates aggregate formation in a Huntington disease mouse model

(2009) Remko de Pril et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Ubiquitin degradation with its substrate, or as a monomer in a ubiquitination-independent mode, provides clues to proteasome regulation

(2009) N. Shabek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Disease-Associated Mutant Ubiquitin Causes Proteasomal Impairment and Enhances the Toxicity of Protein Aggregates

(2009) Elizabeth M. H. Tank et al.   PLoS Genetics

A waterbath method for preparation of RNA from Saccharomyces cerevisiae

(2008) Jing Li et al.   ANALYTICAL BIOCHEMISTRY

Caspase-independent apoptosis in yeast

(2008) Qiuli Liang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Minimal length requirement for proteasomal degradation of ubiquitin-dependent substrates

(2008) Lisette G. G. C. Verhoef et al.   FASEB JOURNAL

Depletion of 26S Proteasomes in Mouse Brain Neurons Causes Neurodegeneration and Lewy-Like Inclusions Resembling Human Pale Bodies

(2008) L. Bedford et al.   JOURNAL OF NEUROSCIENCE

Azetidine-Derived Amino Acids versus Proline Derivatives. Alternative Trends in Reverse Turn Induction

(2008) José Luis Baeza et al.   JOURNAL OF ORGANIC CHEMISTRY

Long-term proteasome dysfunction in the mouse brain by expression of aberrant ubiquitin

(2008) David F. Fischer et al.   NEUROBIOLOGY OF AGING