Review
Cardiac & Cardiovascular Systems
Cicely Anne Dye, Erica Engelstein, Sean Swearingen, Jeanine Murphy, Timothy Larsen, Annabelle Santos Volgman
Summary: Arrhythmias and sudden cardiac death with sexual activity are rare, but recent studies suggest that these events are occurring in younger individuals, with a higher proportion of female decedents than previously described. Open dialogue between the cardiovascular team and the cardiac patient is necessary to provide education and reassurance for safe sexual activity participation.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Jean-Philippe Empana, Ivan Lerner, Eugenie Valentin, Fredrik Folke, Bernd Boettiger, Gunnar Gislason, Martin Jonsson, Mattias Ringh, Frankie Beganton, Wulfran Bougouin, Eloi Marijon, Marieke Blom, Hanno Tan, Xavier Jouven
Summary: This study aimed to determine the incidence of sudden cardiac death and out-of-hospital cardiac arrest in the European Union by utilizing data from four large population-based registries with at least 5 years of data collection.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Review
Medicine, General & Internal
G. Riva, J. Hollenberg
Summary: Out-of-hospital cardiac arrest is a major cause of death in the Western world. Initiating CPR is key to improving survival rates, with early CPR and prompt defibrillation being important factors that influence survival rates.
JOURNAL OF INTERNAL MEDICINE
(2021)
Review
Medicine, General & Internal
Luigi Pannone, Giulio Falasconi, Lorenzo Cianfanelli, Luca Baldetti, Francesco Moroni, Roberto Spoladore, Pasquale Vergara
Summary: Sudden cardiac death is a major cause of mortality in patients with certain heart diseases, with ongoing research focused on improving risk stratification to identify patients who would benefit from ICD implantation. Despite high levels of available data, there are currently no clear recommendations to reduce the risk of sudden cardiac death in these patient populations.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Minna Koivunen, Juho Tynkkynen, Niku Oksala, Markku Eskola, Jussi Hernesniemi
Summary: This study aimed to provide comprehensive information on the epidemiology of sudden cardiac arrests (SCA) and sudden cardiac deaths (SCD) after acute coronary syndrome. Through a retrospective study of 10,316 patients with acute coronary syndrome, it was found that the incidence of SCA and SCD was relatively high, accounting for nearly one-third of deaths due to cardiovascular causes. Patients with ST-elevation myocardial infarction and non-ST-elevation myocardial infarction had a higher incidence of SCA.
AMERICAN HEART JOURNAL
(2023)
Article
Critical Care Medicine
Monique Anderson Starks, Larry R. Jackson, Anne Hellkamp, Sana M. Al-Khatib, Daniel B. Mark, Kevin L. Thomas, Graham Nichol, Kerry L. Lee, Linda Davidson-Ray, Jeanne Poole, Jill Anderson, George Johnson, Gust H. Bardy
Summary: Patients with MI-SCA were found to have similar adjusted risks of all-cause mortality and sudden cardiac death compared to those with MI-no SCA. However, after ICD implantation, MI-SCA patients had higher mortality risks.
Article
Critical Care Medicine
Elizabeth D. Paratz, Emily Nehme, Natalie Heriot, Kenneth Bissland, Stephanie Rowe, Louise Fahy, David Anderson, Dion Stub, Andre La Gerche, Ziad Nehme
Summary: The global aging population and increasing rates of out-of-hospital cardiac arrest (OHCA) in the elderly, especially those aged >= 80 years, have led to the need for identifying predictors of survival in this age group. This study found that witnessed OHCA and shockable rhythm were the most important factors predicting survival. A simplified prognostic score, the '15/5/0' score, was derived to determine which elderly patients would benefit most from advanced resuscitation measures.
Article
Cardiac & Cardiovascular Systems
Elizabeth P. P. Held, Kyndaron Reinier, Harpriya Chugh, Audrey Uy-Evanado, Jonathan Jui, Sumeet S. S. Chugh
Summary: This study characterizes and evaluates the burden of recurrent out-of-hospital sudden cardiac arrest (SCA) among survivors in a large US community. It found that at least 10% of SCA survivors experienced recurrent SCA, with a significant percentage recurring despite treatment for reversible causes. The study suggests the need for a renewed focus on assessing cardiac health and managing potential risk factors in SCA survivors.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY
(2022)
Letter
Allergy
Matthieu Groh, Marc Pineton de Chambrun, Jean-Louis Georges, Kewin Panel, Guillaume Lefevre, Jean-Emmanuel Kahn, Colas Tcherakian, Raphaele Convers-Domart
Summary: Eosinophilia-related coronary vasospasm should be considered in patients with chest pain and elevated eosinophil counts. Treatment aiming to normalize absolute eosinophil counts is essential, with benralizumab showing promise as a steroid-free option that warrants further investigation.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE
(2021)
Article
Cardiac & Cardiovascular Systems
Santo Ricceri, James W. Salazar, Andrew A. Vu, Eric Vittinghoff, Ellen Moffatt, Zian H. Tseng
Summary: In this 4-year countywide study of OHCAs, only one-third were sudden, of which one-half were resuscitated to hospitalization and 1 in 5 survived to discharge. Arrhythmic cause predicted survival and nearly one-half of nonsurvivors had nonarrhythmic causes, suggesting that SCA survivors are not equivalent to SCDs. Early identification of nonarrhythmic SCAs, such as neurologic emergencies, may be a target to improve OHCA survival.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Archana Ramireddy, Harpriya S. Chugh, Kyndaron Reinier, Audrey Uy-Evanado, Eric C. Stecker, Jonathan Jui, Sumeet S. Chugh
Summary: In the general population, women were more likely than men to suffer SCD during nighttime hours and female sex was an independent predictor of nighttime events. Respiratory suppression is a concern, and caution is advisable when prescribing central nervous system-affecting medications to patients at an increased risk of SCD, especially women.
Article
Genetics & Heredity
Takuma Yamamoto, Rie Sano, Aya Miura, Mai Imasaka, Yoshiro Naito, Minori Nishiguchi, Kensuke Ihara, Naruhito Otani, Yoshihiko Kominato, Masaki Ohmuraya, Hidehito Kuroyanagi, Hajime Nishio
Summary: This study identified the manifestation of I536T-RBM20 variant in human patients and its effects in a mouse model. The variant alters gene splicing and affects gene expression, but does not cause dilated cardiomyopathy.
JOURNAL OF MOLECULAR MEDICINE-JMM
(2022)
Review
Cardiac & Cardiovascular Systems
Paul Khairy, Michael J. Silka, Jeremy P. Moore, James A. DiNardo, Jim T. Vehmeijer, Mary N. Sheppard, Alexander van de Bruaene, Marie-A Chaix, Margarita Brida, Benjamin M. Moore, Maully J. Shah, Blandine Mondesert, Seshadri Balaji, Michael A. Gatzoulis, Magalie Ladouceur
Summary: Sudden cardiac death (SCD) is a significant cause of death in patients with congenital heart disease (CHD). Current research is mainly based on observational studies and clinical experience, with some limitations. Certain higher-risk underlying diseases have been identified, but distinguishing SCD from non-cardiac sudden deaths is often challenging without autopsies. High-quality cardiopulmonary resuscitation is crucial for improving outcomes. Risk stratification for preventing SCD should consider the probability of shockable rhythm, other causes of death, complications of implantable cardioverter-defibrillator (ICD) therapy, and associated costs. Risk scores and specific guidelines and recommendations for CHD have been proposed. Additionally, the subcutaneous ICD is an attractive alternative. Further improvement in SCD-related outcomes requires a multidimensional research approach.
EUROPEAN HEART JOURNAL
(2022)
Article
Transplantation
Simonetta Genovesi, Giuseppe Boriani, Adrian Covic, Robin W. M. Vernooij, Christian Combe, Alexandru Burlacu, Andrew Davenport, Mehmet Kanbay, Dimitrios Kirmizis, Daniel Schneditz, Frank van der Sande, Carlo Basile
Summary: SCD and SCA in ESKD patients are different clinical situations with potentially different management strategies, with modifiable risk factors such as potassium and calcium concentration in dialysate. In this population, fatal arrhythmias may be due more frequently to bradyarrhythmias than to tachyarrhythmias.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2021)
Article
Cardiac & Cardiovascular Systems
Michal Simiera, Dawid Miskowiec, Ewa Mrozowska-Peruga, Marta Nowakowska, Magdalena Klosinska, Jaroslaw Damian Kasprzak
Summary: This study found that early coronary angiography can improve outcomes in patients after cardiac arrest. Lower blood oxygen saturation, lower ejection fraction, and non-ST-segement elevation myocardial infarction were identified as independent risk factors for death.
KARDIOLOGIA POLSKA
(2022)