Switched Memory B Cells Are Increased in Oligoarticular and Polyarticular Juvenile Idiopathic Arthritis and Their Change Over Time Is Related to Response to Tumor Necrosis Factor Inhibitors

B-cell activation with CD40L or CpG measures the function of B-cell subsets and identifies specific defects in immunodeficient patients

(2016) Emiliano Marasco et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Human B-cell memory is shaped by age- and tissue-specific T-independent and GC-dependent events

(2016) Alaitz Aranburu et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Global Analyses of Human Immune Variation Reveal Baseline Predictors of Postvaccination Responses

(2014) John S. Tsang et al.   CELL

CpG Drives Human Transitional B Cells to Terminal Differentiation and Production of Natural Antibodies

(2014) F. Capolunghi et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Anti-Tumor Necrosis Factor Therapy in Rheumatoid Arthritis Inhibits Memory B Lymphocytes via Effects on Lymphoid Germinal Centers and Follicular Dendritic Cell Networks

(2014) J. H. Anolik et al.   JOURNAL OF IMMUNOLOGY

Abatacept Reduces Levels of Switched Memory B Cells, Autoantibodies, and Immunoglobulins in Patients with Rheumatoid Arthritis

(2014) M. Scarsi et al.   JOURNAL OF RHEUMATOLOGY

Distinct Effects of Methotrexate and Etanercept on the B Cell Compartment in Patients With Juvenile Idiopathic Arthritis

(2014) Stephanie Glaesener et al.   Arthritis & Rheumatology

Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis

(2013) Anne Hinks et al.   NATURE GENETICS

CSK regulatory polymorphism is associated with systemic lupus erythematosus and influences B-cell signaling and activation

(2012) Nataly Manjarrez-Orduño et al.   NATURE GENETICS

New takes on categorization and treatment

(2012) Alberto Martini   Nature Reviews Rheumatology

Impact of IL-6 receptor inhibition on human memory B cells in vivo: impaired somatic hypermutation in preswitch memory B cells and modulation of mutational targeting in memory B cells

(2011) K. Muhammad et al.   ANNALS OF THE RHEUMATIC DISEASES

Activated memory B cells may function as antigen-presenting cells in the joints of children with juvenile idiopathic arthritis

(2011) Henner Morbach et al.   ARTHRITIS AND RHEUMATISM

Juvenile idiopathic arthritis: state of the art and future perspectives

(2010) A. Martini et al.   ANNALS OF THE RHEUMATIC DISEASES

Biologic similarities based on age at onset in oligoarticular and polyarticular subtypes of juvenile idiopathic arthritis

(2010) Michael G. Barnes et al.   ARTHRITIS AND RHEUMATISM

Antinuclear antibody-positive patients should be grouped as a separate category in the classification of juvenile idiopathic arthritis

(2010) Angelo Ravelli et al.   ARTHRITIS AND RHEUMATISM

B cell subsets in healthy children: Reference values for evaluation of B cell maturation process in peripheral blood

(2010) Barbara Piątosa et al.   CYTOMETRY PART B-CLINICAL CYTOMETRY

Phenotypic and functional characterization of switch memory B cells from patients with oligoarticular juvenile idiopathic arthritis

(2009) Anna Corcione et al.   ARTHRITIS RESEARCH & THERAPY

Anti-CD20 therapy in patients with rheumatoid arthritis: Predictors of response and B cell subset regeneration after repeated treatment

(2008) Petra Roll et al.   ARTHRITIS AND RHEUMATISM