Anti-diabetic effect of β-D-mannuronic acid (M2000) as a novel NSAID with immunosuppressive property on insulin production, blood glucose, and inflammatory markers in the experimental diabetes model

The potent suppressive effect of β- d -mannuronic acid (M2000) on molecular expression of the TLR/NF-kB Signaling Pathway in ankylosing spondylitis patients

(2017) Maryam Roozbehkia et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Introduction of β- d -mannuronic acid (M2000) as a novel NSAID with immunosuppressive property based on COX-1/COX-2 activity and gene expression

(2017) Abbas Mirshafiey et al.   Pharmacological Reports

Pharmacological effects of β- d -mannuronic acid (M2000) on miR-146a, IRAK1, TRAF6 and NF-κB gene expression, as target molecules in inflammatory reactions

(2017) Seyed Shahabeddin Mortazavi-Jahromi et al.   Pharmacological Reports

M2000 (β-D-Mannuronic Acid) as a Novel Antagonist for Blocking the TLR2 and TLR4 Downstream Signalling Pathway

(2017) S. Aletaha et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Effects of β-D-mannuronic acid, as a novel non-steroidal anti-inflammatory medication within immunosuppressive properties, on IL17, RORγt, IL4 and GATA3 gene expressions in rheumatoid arthritis patients

(2017) Anis Barati et al.   Drug Design Development and Therapy

Targeting of crosstalk between tumor and tumor microenvironment by β-D mannuronic acid (M2000) in murine breast cancer model

(2017) Fatemeh Hosseini et al.   Cancer Medicine

Preclinical assessment ofβ-d-mannuronic acid (M2000) as a non-steroidal anti-inflammatory drug

(2015) Mohammad Javad Fattahi et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Free fatty acids in the presence of high glucose amplify monocyte inflammation via Toll-like receptors

(2010) Mohan R. Dasu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Increased Toll-Like Receptor (TLR) Activation and TLR Ligands in Recently Diagnosed Type 2 Diabetic Subjects

(2010) M. R. Dasu et al.   DIABETES CARE

Regulation by 1, 25-dihydroxy-vitamin D3 on altered TLRs expression and response to ligands of monocyte from autoimmune diabetes

(2009) Tao Du et al.   CLINICA CHIMICA ACTA

Global estimates of the prevalence of diabetes for 2010 and 2030

(2009) J.E. Shaw et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Elevated Toll-Like Receptor 4 Expression and Signaling in Muscle From Insulin-Resistant Subjects

(2008) S. M. Reyna et al.   DIABETES

Diabetes-Related Microvascular and Macrovascular Diseases in the Physical Therapy Setting

(2008) W Todd Cade   PHYSICAL THERAPY

Mechanisms of Disease: advanced glycation end-products and their receptor in inflammation and diabetes complications

(2008) Shi Fang Yan et al.   Nature clinical practice. Endocrinology & metabolism

Toll-like receptor 2 plays a critical role in the progression of atherosclerosis that is independent of dietary lipids

(2007) Xinyan Liu et al.   ATHEROSCLEROSIS

Increased Toll-Like Receptor (TLR) 2 and TLR4 Expression in Monocytes from Patients with Type 1 Diabetes: Further Evidence of a Proinflammatory State

(2007) Sridevi Devaraj et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM