Cell Transplantation for Spinal Cord Injury: Tumorigenicity of Induced Pluripotent Stem Cell-Derived Neural Stem/Progenitor Cells

Autologous Induced Stem-Cell–Derived Retinal Cells for Macular Degeneration

(2017) Michiko Mandai et al.   NEW ENGLAND JOURNAL OF MEDICINE

Evaluation of the immunogenicity of human iPS cell-derived neural stem/progenitor cells in vitro

(2017) Masahiro Ozaki et al.   Stem Cell Research

Whole-Genome DNA Methylation Analyses Revealed Epigenetic Instability in Tumorigenic Human iPS Cell-Derived Neural Stem/Progenitor Cells

(2017) Tsuyoshi Iida et al.   STEM CELLS

Fail-Safe System against Potential Tumorigenicity after Transplantation of iPSC Derivatives

(2017) Go Itakura et al.   Stem Cell Reports

An epigenetic gateway to brain tumor cell identity

(2016) Stephen C Mack et al.   NATURE NEUROSCIENCE

MicroRNA-302 switch to identify and eliminate undifferentiated human pluripotent stem cells

(2016) Callum J. C. Parr et al.   Scientific Reports

Preventing Pluripotent Cell Teratoma in Regenerative Medicine Applied to Hematology Disorders

(2016) Aurelie Bedel et al.   Stem Cells Translational Medicine

Pretreatment with a γ-Secretase Inhibitor Prevents Tumor-like Overgrowth in Human iPSC-Derived Transplants for Spinal Cord Injury

(2016) Toshiki Okubo et al.   Stem Cell Reports

Transplanted Human Induced Pluripotent Stem Cell-Derived Neural Progenitor Cells Do Not Promote Functional Recovery of Pharmacologically Immunosuppressed Mice with Contusion Spinal Cord Injury

(2015) Yuriy Pomeshchik et al.   CELL TRANSPLANTATION

Long-Term Safety Issues of iPSC-Based Cell Therapy in a Spinal Cord Injury Model: Oncogenic Transformation with Epithelial-Mesenchymal Transition

(2015) Satoshi Nori et al.   Stem Cell Reports

Effects of Integrating and Non-Integrating Reprogramming Methods on Copy Number Variation and Genomic Stability of Human Induced Pluripotent Stem Cells

(2015) Xiangjin Kang et al.   PLoS One

Long-Distance Axonal Growth from Human Induced Pluripotent Stem Cells after Spinal Cord Injury

(2014) Paul Lu et al.   NEURON

Global prevalence and incidence of traumatic spinal cord injury

(2014) Michael Fehlings et al.   Clinical Epidemiology

Caudalized human iPSC-derived neural progenitor cells produce neurons and glia but fail to restore function in an early chronic spinal cord injury model

(2013) Samuel E. Nutt et al.   EXPERIMENTAL NEUROLOGY

Review of transplantation of neural stem/progenitor cells for spinal cord injury

(2013) Andrea J. Mothe et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

The tumourigenicity of iPS cells and their differentiated derivates

(2013) Zhiqiang Liu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Time-dependent changes in the microenvironment of injured spinal cord affects the therapeutic potential of neural stem cell transplantation for spinal cord injury

(2013) Soraya Nishimura et al.   Molecular Brain

Cell transplantation therapies for spinal cord injury focusing on induced pluripotent stem cells

(2012) Masaya Nakamura et al.   CELL RESEARCH

Pre-Evaluated Safe Human iPSC-Derived Neural Stem Cells Promote Functional Recovery after Spinal Cord Injury in Common Marmoset without Tumorigenicity

(2012) Yoshiomi Kobayashi et al.   PLoS One

Treatment of a Mouse Model of Spinal Cord Injury by Transplantation of Human Induced Pluripotent Stem Cell-Derived Long-Term Self-Renewing Neuroepithelial-Like Stem Cells

(2012) Yusuke Fujimoto et al.   STEM CELLS

Assessing the Safety of Stem Cell Therapeutics

(2011) Chris E.P. Goldring et al.   Cell Stem Cell

Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells

(2011) Ryan Lister et al.   NATURE

Grafted human-induced pluripotent stem-cell-derived neurospheres promote motor functional recovery after spinal cord injury in mice

(2011) S. Nori et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA

(2010) Luigi Warren et al.   Cell Stem Cell

Epigenetic memory in induced pluripotent stem cells

(2010) K. Kim et al.   NATURE

Geron trial resumes, but standards for stem cell trials remain elusive

(2010) Stephen Strauss   NATURE BIOTECHNOLOGY

Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells

(2010) Jose M Polo et al.   NATURE BIOTECHNOLOGY

Therapeutic potential of appropriately evaluated safe-induced pluripotent stem cells for spinal cord injury

(2010) Osahiko Tsuji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oct4-Induced Pluripotency in Adult Neural Stem Cells

(2009) Jeong Beom Kim et al.   CELL

piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells

(2009) Knut Woltjen et al.   NATURE

Variation in the safety of induced pluripotent stem cell lines

(2009) Kyoko Miura et al.   NATURE BIOTECHNOLOGY

Generation of induced pluripotent stem cells from neural stem cells

(2009) Jeong Beom Kim et al.   Nature Protocols

Roles of ES Cell-Derived Gliogenic Neural Stem/Progenitor Cells in Functional Recovery after Spinal Cord Injury

(2009) Gentaro Kumagai et al.   PLoS One

Dissecting direct reprogramming through integrative genomic analysis

(2008) Tarjei S. Mikkelsen et al.   NATURE

Protection and repair of the injured spinal cord: a review of completed, ongoing, and planned clinical trials for acute spinal cord injury

(2008) Gregory W. J. Hawryluk et al.   Neurosurgical Focus