IKK promotes cytokine-induced and cancer-associated AMPK activity and attenuates phenformin-induced cell death in LKB1-deficient cells

Metformin activation of AMPK suppresses AGE-induced inflammatory response in hNSCs

(2017) Ming-Min Chung et al.   EXPERIMENTAL CELL RESEARCH

Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptor-associated kinase-4 phosphorylation

(2017) Sarah J. Mancini et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

IKKβ promotes metabolic adaptation to glutamine deprivation via phosphorylation and inhibition of PFKFB3

(2016) Michael A. Reid et al.   GENES & DEVELOPMENT

Heightening Energetic Stress Selectively Targets LKB1-Deficient Non-Small Cell Lung Cancers

(2015) M. Momcilovic et al.   CANCER RESEARCH

2016 update of the PRIDE database and its related tools

(2015) Juan Antonio Vizcaíno et al.   NUCLEIC ACIDS RESEARCH

Discovery of Type II Inhibitors of TGFβ-Activated Kinase 1 (TAK1) and Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2)

(2014) Li Tan et al.   JOURNAL OF MEDICINAL CHEMISTRY

LKB1 Inactivation Dictates Therapeutic Response of Non-Small Cell Lung Cancer to the Metabolism Drug Phenformin

(2013) David B. Shackelford et al.   CANCER CELL

AMP Is a True Physiological Regulator of AMP-Activated Protein Kinase by Both Allosteric Activation and Enhancing Net Phosphorylation

(2013) Graeme J. Gowans et al.   Cell Metabolism

The IκB kinase complex in NF-κB regulation and beyond

(2013) Michael Hinz et al.   EMBO REPORTS

Molecular control of the NEMO family of ubiquitin-binding proteins

(2013) Kristopher Clark et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

NF- B, the first quarter-century: remarkable progress and outstanding questions

(2012) M. S. Hayden et al.   GENES & DEVELOPMENT

TBK-1 Promotes Autophagy-Mediated Antimicrobial Defense by Controlling Autophagosome Maturation

(2012) Manohar Pilli et al.   IMMUNITY

TAK1, more than just innate immunity

(2012) Liang Dai et al.   IUBMB LIFE

NEMO Ensures Signaling Specificity of the Pleiotropic IKKβ by Directing Its Kinase Activity toward IκBα

(2012) Bärbel Schröfelbauer et al.   MOLECULAR CELL

p85α SH2 Domain Phosphorylation by IKK Promotes Feedback Inhibition of PI3K and Akt in Response to Cellular Starvation

(2012) William C. Comb et al.   MOLECULAR CELL

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nuclear factor-κB, p53, and mitochondria: regulation of cellular metabolism and the Warburg effect

(2012) Renée F. Johnson et al.   TRENDS IN BIOCHEMICAL SCIENCES

Hydrophilic interaction chromatography of nucleoside triphosphates with temperature as a separation parameter

(2011) Elin Johnsen et al.   JOURNAL OF CHROMATOGRAPHY A

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

(2011) Maria M. Mihaylova et al.   NATURE CELL BIOLOGY

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

AMPK Is a Direct Adenylate Charge-Regulated Protein Kinase

(2011) J. S. Oakhill et al.   SCIENCE

A role for AMPK in increased insulin action after serum starvation

(2010) James Kain Ching et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

A single NFκB system for both canonical and non-canonical signaling

(2010) Vincent Feng-Sheng Shih et al.   CELL RESEARCH

Autoactivation of Transforming Growth Factor β-activated Kinase 1 Is a Sequential Bimolecular Process

(2010) Roland Scholz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IKK-dependent, NF-κB-independent control of autophagic gene expression

(2010) W C Comb et al.   ONCOGENE

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

(2010) D. F. Egan et al.   SCIENCE

Basal autophagy induction without AMP-activated protein kinase under low glucose conditions

(2009) Tyisha Williams et al.   Autophagy

AMP-activated protein kinase confers protection against TNF-α-induced cardiac cell death

(2009) Girish Kewalramani et al.   CARDIOVASCULAR RESEARCH

TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells

(2009) Griselda Herrero-Martín et al.   EMBO JOURNAL

The IKK complex contributes to the induction of autophagy

(2009) Alfredo Criollo et al.   EMBO JOURNAL

AMPK in Health and Disease

(2009) Gregory R. Steinberg et al.   PHYSIOLOGICAL REVIEWS

Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro

(2008) James A. Dykens et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY