The depalmitoylase APT1 directs the asymmetric partitioning of Notch and Wnt signaling during cell division

Developmental signaling pathways regulating mammary stem cells and contributing to the etiology of triple-negative breast cancer

(2016) Maria Cristina Rangel et al.   BREAST CANCER RESEARCH AND TREATMENT

Inhibition of DHHC20-Mediated EGFR Palmitoylation Creates a Dependence on EGFR Signaling

(2016) Kristin B. Runkle et al.   MOLECULAR CELL

ZDHHC7-mediated S-palmitoylation of Scribble regulates cell polarity

(2016) Baoen Chen et al.   Nature Chemical Biology

Protein Depalmitoylation Is Induced by Wnt5a and Promotes Polarized Cell Behavior

(2015) Wei Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness

(2015) P. Katajisto et al.   SCIENCE

Triple negative breast cancers comprise a highly tumorigenic cell subpopulation detectable by its high responsiveness to a Sox2 regulatory region 2 (SRR2) reporter

(2015) Karen Jung et al.   Oncotarget

β-Catenin Is Required for the Tumorigenic Behavior of Triple-Negative Breast Cancer Cells

(2015) Jinhua Xu et al.   PLoS One

The Autodepalmitoylating Activity of APT Maintains the Spatial Organization of Palmitoylated Membrane Proteins

(2014) Nachiket Vartak et al.   BIOPHYSICAL JOURNAL

Cancer Epigenetics: Tumor Heterogeneity, Plasticity of Stem-like States, and Drug Resistance

(2014) Hariharan Easwaran et al.   MOLECULAR CELL

Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers

(2014) Allison S. Cleary et al.   NATURE

Lis1 regulates asymmetric division in hematopoietic stem cells and in leukemia

(2014) Bryan Zimdahl et al.   NATURE GENETICS

Covalent lipid modifications of proteins

(2013) Marilyn D. Resh   CURRENT BIOLOGY

Triple negative breast cancer initiating cell subsets differ in functional and molecular characteristics and in γ-secretase inhibitor drug responses

(2013) Diana J. Azzam et al.   EMBO Molecular Medicine

Dynamic Palmitoylation Links Cytosol-Membrane Shuttling of Acyl-protein Thioesterase-1 and Acyl-protein Thioesterase-2 with That of Proto-oncogene H-Ras Product and Growth-associated Protein-43

(2013) Eryan Kong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a Novel Prenyl and Palmitoyl Modification at the CaaX Motif of Cdc42 That Regulates RhoGDI Binding

(2013) A. Nishimura et al.   MOLECULAR AND CELLULAR BIOLOGY

Myc is required for β-catenin-mediated mammary stem cell amplification and tumorigenesis

(2013) Mejdi Moumen et al.   Molecular Cancer

Influence of tumour micro-environment heterogeneity on therapeutic response

(2013) Melissa R. Junttila et al.   NATURE

A Localized Wnt Signal Orients Asymmetric Stem Cell Division in Vitro

(2013) S. J. Habib et al.   SCIENCE

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

Lgr4 regulates mammary gland development and stem cell activity through the pluripotency transcription factor Sox2

(2013) Ying Wang et al.   STEM CELLS

Establishment of a robust single axis of cell polarity by coupling multiple positive feedback loops

(2013) Tina Freisinger et al.   Nature Communications

Stochastic model for cell polarity

(2012) Ankit Gupta   ANNALS OF APPLIED PROBABILITY

Evolution of the cancer genome

(2012) Lucy R. Yates et al.   NATURE REVIEWS GENETICS

Cutaneous papillomavirus E6 oncoproteins associate with MAML1 to repress transactivation and NOTCH signaling

(2012) N Brimer et al.   ONCOGENE

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Protein palmitoylation and subcellular trafficking

(2011) Clara Aicart-Ramos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Symmetry breaking and the establishment of cell polarity in budding yeast

(2011) Jayme M Johnson et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Asymmetric Proteasome Segregation as a Mechanism for Unequal Partitioning of the Transcription Factor T-bet during T Lymphocyte Division

(2011) John T. Chang et al.   IMMUNITY

Functional characterization of osteosarcoma cell lines provides representative models to study the human disease

(2011) Alexander B Mohseny et al.   LABORATORY INVESTIGATION

Rho GTPase Cdc42 Is a Direct Interacting Partner of Adenomatous Polyposis Coli Protein and Can Alter Its Cellular Localization

(2011) Thankiah Sudhaharan et al.   PLoS One

Slow-Cycling Therapy-Resistant Cancer Cells

(2011) Nathan Moore et al.   STEM CELLS AND DEVELOPMENT

Cyclin D1 Kinase Activity Is Required for the Self-Renewal of Mammary Stem and Progenitor Cells that Are Targets of MMTV-ErbB2 Tumorigenesis

(2010) Rinath Jeselsohn et al.   CANCER CELL

The Origins and Implications of Intratumor Heterogeneity

(2010) F. Michor et al.   Cancer Prevention Research

Palmitoylation and depalmitoylation dynamics at a glance

(2010) Elizabeth Conibear et al.   JOURNAL OF CELL SCIENCE

Protein palmitoylation in neuronal development and synaptic plasticity

(2010) Yuko Fukata et al.   NATURE REVIEWS NEUROSCIENCE

Palmitoylation regulates raft affinity for the majority of integral raft proteins

(2010) I. Levental et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Notch Activation Differentially Regulates Renal Progenitors Proliferation and Differentiation Toward the Podocyte Lineage in Glomerular Disorders

(2010) Laura Lasagni et al.   STEM CELLS

c-Myc affects mRNA translation, cell proliferation and progenitor cell function in the mammary gland

(2009) Tina Stoelzle et al.   BMC BIOLOGY

The Tumor Suppressor p53 Regulates Polarity of Self-Renewing Divisions in Mammary Stem Cells

(2009) Angelo Cicalese et al.   CELL

aPKC Phosphorylates Miranda to Polarize Fate Determinants during Neuroblast Asymmetric Cell Division

(2009) Scott X. Atwood et al.   CURRENT BIOLOGY

Dividing cellular asymmetry: asymmetric cell division and its implications for stem cells and cancer

(2009) R. A. Neumuller et al.   GENES & DEVELOPMENT

Live-imaging of single stem cells within their niche reveals that a U3snoRNP component segregates asymmetrically and is required for self-renewal in Drosophila

(2009) Pierre Fichelson et al.   NATURE CELL BIOLOGY

Linking Cell Cycle to Asymmetric Division: Aurora-A Phosphorylates the Par Complex to Regulate Numb Localization

(2008) Frederik Wirtz-Peitz et al.   CELL

Notch Signaling Regulates Mammary Stem Cell Function and Luminal Cell-Fate Commitment

(2008) Toula Bouras et al.   Cell Stem Cell

Dickkopf (Dkk) 1 promotes the differentiation of mouse embryonic stem cells toward neuroectoderm

(2008) Xiang Bo Kong et al.   IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL

Palmitoylation and localisation of RAS isoforms are modulated by the hypervariable linker domain

(2008) Alex J. Laude et al.   JOURNAL OF CELL SCIENCE

On the spontaneous emergence of cell polarity

(2008) Steven J. Altschuler et al.   NATURE

Mei-P26 regulates microRNAs and cell growth in the Drosophila ovarian stem cell lineage

(2008) Ralph A. Neumüller et al.   NATURE

A core Klf circuitry regulates self-renewal of embryonic stem cells

(2008) Jianming Jiang et al.   NATURE CELL BIOLOGY

Detection and Characterization of CD133+ Cancer Stem Cells in Human Solid Tumours

(2008) Virginia Tirino et al.   PLoS One

Asymmetric mitosis: Unequal segregation of proteins destined for degradation

(2008) L. C. Fuentealba et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA