CRISPR/Cas9-induced shank3b mutant zebrafish display autism-like behaviors

SHANK proteins: roles at the synapse and in autism spectrum disorder

(2017) Patricia Monteiro et al.   NATURE REVIEWS NEUROSCIENCE

Developmental profiling of ASD-related shank3 transcripts and their differential regulation by valproic acid in zebrafish

(2016) Chun-xue Liu et al.   DEVELOPMENT GENES AND EVOLUTION

Erratum: Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice

(2016) C Vicidomini et al.   MOLECULAR PSYCHIATRY

SHANK3 Deficiency Impairs Heat Hyperalgesia and TRPV1 Signaling in Primary Sensory Neurons

(2016) Qingjian Han et al.   NEURON

Estrogens Suppress a Behavioral Phenotype in Zebrafish Mutants of the Autism Risk Gene, CNTNAP2

(2016) Ellen J. Hoffman et al.   NEURON

Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects

(2016) Yang Zhou et al.   NEURON

Altered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism

(2016) Xiaoming Wang et al.   Nature Communications

Altered Striatal Synaptic Function and Abnormal Behaviour inShank3Exon4-9 Deletion Mouse Model of Autism

(2015) Thomas C. Jaramillo et al.   Autism Research

Switching to zebrafish neurobehavioral models: The obsessive–compulsive disorder paradigm

(2015) Davide D’Amico et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Two knockdown models of the autism genes SYNGAP1 and SHANK3 in zebrafish produce similar behavioral phenotypes associated with embryonic disruptions of brain morphogenesis

(2015) Robert A. Kozol et al.   HUMAN MOLECULAR GENETICS

Shank synaptic scaffold proteins: keys to understanding the pathogenesis of autism and other synaptic disorders

(2015) Carlo Sala et al.   JOURNAL OF NEUROCHEMISTRY

Autism-Associated Insertion Mutation (InsG) of Shank3 Exon 21 Causes Impaired Synaptic Transmission and Behavioral Deficits

(2015) H. E. Speed et al.   JOURNAL OF NEUROSCIENCE

Zebrafish as an emerging model for studying complex brain disorders

(2014) Allan V. Kalueff et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

22q13.2q13.32 genomic regions associated with severity of speech delay, developmental delay and physical features in Phelan–McDermid syndrome

(2013) Sara M. Sarasua et al.   GENETICS IN MEDICINE

Efficient genome editing in zebrafish using a CRISPR-Cas system

(2013) Woong Y Hwang et al.   NATURE BIOTECHNOLOGY

Modeling Autism by SHANK Gene Mutations in Mice

(2013) Yong-hui Jiang et al.   NEURON

Developing zebrafish models of autism spectrum disorder (ASD)

(2013) Adam Michael Stewart et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Towards a Comprehensive Catalog of Zebrafish Behavior 1.0 and Beyond

(2013) Allan V. Kalueff et al.   Zebrafish

SHANK3 haploinsufficiency: a “common” but underdiagnosed highly penetrant monogenic cause of autism spectrum disorders

(2013) Catalina Betancur et al.   Molecular Autism

Prospective investigation of autism and genotype-phenotype correlations in 22q13 deletion syndrome and SHANK3 deficiency

(2013) Latha Soorya et al.   Molecular Autism

Autism-Associated Mutations in ProSAP2/Shank3 Impair Synaptic Transmission and Neurexin-Neuroligin-Mediated Transsynaptic Signaling

(2012) M. H. Arons et al.   JOURNAL OF NEUROSCIENCE

Reduced Excitatory Neurotransmission and Mild Autism-Relevant Phenotypes in Adolescent Shank3 Null Mutant Mice

(2012) M. Yang et al.   JOURNAL OF NEUROSCIENCE

Maturation of shoaling behavior is accompanied by changes in the dopaminergic and serotoninergic systems in zebrafish

(2011) Christine Buske et al.   DEVELOPMENTAL PSYCHOBIOLOGY

Importance of Shank3 Protein in Regulating Metabotropic Glutamate Receptor 5 (mGluR5) Expression and Signaling at Synapses

(2011) Chiara Verpelli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Association between deletion size and important phenotypes expands the genomic region of interest in Phelan-McDermid syndrome (22q13 deletion syndrome)

(2011) S. M. Sarasua et al.   JOURNAL OF MEDICAL GENETICS

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

(2011) João Peça et al.   NATURE

Synaptophysin Regulates the Kinetics of Synaptic Vesicle Endocytosis in Central Neurons

(2011) Sung E. Kwon et al.   NEURON

Shoaling in zebrafish: what we don’t know

(2011) Noam Y. Miller et al.   REVIEWS IN THE NEUROSCIENCES

Postsynaptic ProSAP/Shank scaffolds in the cross-hair of synaptopathies

(2011) Andreas M. Grabrucker et al.   TRENDS IN CELL BIOLOGY

Molecular Mechanisms Generating and Stabilizing Terminal 22q13 Deletions in 44 Subjects with Phelan/McDermid Syndrome

(2011) Maria Clara Bonaglia et al.   PLoS Genetics

Use of zebrafish as a model to understand mechanisms of addiction and complex neurobehavioral phenotypes

(2010) Priya Mathur et al.   NEUROBIOLOGY OF DISEASE

De novo mutations in the gene encoding the synaptic scaffolding proteinSHANK3in patients ascertained for schizophrenia

(2010) Julie Gauthier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early differences in epithalamic left–right asymmetry influence lateralization and personality of adult zebrafish

(2009) Marco Dadda et al.   BEHAVIOURAL BRAIN RESEARCH

A glimmer of light for neuropsychiatric disorders

(2008) Steven E. Hyman   NATURE