Article
Surgery
Ryan Howard, Andrew Ryan, Hsou Mei Hu, Craig S. Brown, Jennifer Waljee, Mark C. Bicket, Michael Englesbe, Chad M. Brummett
Summary: This study aims to evaluate the association between evidence-based opioid prescribing guidelines and new persistent opioid use after surgery. Using Medicare claims, the study compared opioid-naive patients who underwent surgery in Michigan, where evidence-based guidelines were released, with those who underwent surgery outside of Michigan. The results showed a significant reduction in the incidence of new persistent opioid use and the quantity of opioids prescribed after the release of the guidelines.
Article
Respiratory System
Jarred R. Mondonedo, Alexander A. Brescia, Melissa J. Clark, Matthew L. Chang, Shannon Jiang, Chang He, Robert J. Welsh, Andrew M. Popoff, Mohan G. Kulkarni, Shelly C. Lall, Jerry W. Pratt, Kumari N. Adams, Raed M. Alnajjar, James R. Martin, Divyakant B. Gandhi, Chad M. Brummett, Andrew C. Chang, Kiran H. Lagisetty
Summary: Prescribing guidelines for post-discharge opioid use after lung cancer resection are lacking. A study examined opioid prescribing and patient-reported use to develop evidence-based guidelines. The study found that surgical approach, in-hospital opioid use before discharge, and patient-reported post-discharge use should inform prescribing recommendations.
JOURNAL OF THORACIC DISEASE
(2023)
Article
Surgery
Julia D. Kelm, Staci T. Aubry, Anne H. Cain-Nielsen, John W. Scott, Bryant W. Oliphant, Naveen F. Sangji, Jennifer F. Waljee, Mark R. Hemmila
Summary: This study aimed to evaluate the impact of opioid prescribing policies on trauma patients. The results showed that after the implementation of the policy, the amount of opioids prescribed at discharge for trauma patients decreased by approximately one-half, and there was no compensatory increase in subsequent refill prescriptions. These findings suggest that the implementation of opioid prescribing policies has a positive effect on reducing opioid use.
Article
Cardiac & Cardiovascular Systems
Alexander A. Brescia, Melissa J. Clark, Patricia F. Theurer, Shelly C. Lall, Hassan W. Nemeh, Richard S. Downey, David E. Martin, Reza R. Dabir, Zewditu E. Asfaw, Phillip L. Robinson, Steven D. Harrington, Divyakant B. Gandhi, Jennifer F. Waljee, Michael J. Englesbe, Chad M. Brummett, Richard L. Prager, Donald S. Likosky, Karen M. Kim, Kiran H. Lagisetty
Summary: The study found that an opioid prescribing recommendation post-cardiac surgery was effective in reducing both prescription size and patient use. Prescription after surgery should be guided by inpatient opioid use.
ANNALS OF THORACIC SURGERY
(2021)
Article
Clinical Neurology
Gerardo A. Arwi, Penelope H. R. Tuffin, Stephan A. Schug
Summary: Compliance with discharge analgesia prescribing guidelines in a tertiary Australian hospital has increased but still needs improvement. The study reveals high rates of unused opioids and improper storage and disposal of pain medication.
JOURNAL OF PAIN RESEARCH
(2022)
Article
Otorhinolaryngology
Tanvi Rana, Kelly Daniels, Sophia Dang, Jonathan C. C. Li, Cecilia G. G. Freeman, Alexander Duffy, Joseph Curry, Adam Luginbuhl, Elizabeth Cottrill, David Cognetti
Summary: The implementation of opioid-prescribing guidelines and the use of multimodal analgesia significantly reduced the amount of opioids prescribed for various procedures without affecting patient satisfaction.
LARYNGOSCOPE INVESTIGATIVE OTOLARYNGOLOGY
(2023)
Article
Medicine, General & Internal
Emma E. McGinty, Mark C. Bicket, Nicholas J. Seewald, Elizabeth A. Stuart, G. Caleb Alexander, Colleen L. Barry, Alexander D. McCourt, Lainie Rutkow
Summary: This study did not identify any changes in opioid prescribing or nonopioid pain treatment attributable to state laws. However, the results may not be applicable to non-commercially insured populations due to data limitations.
ANNALS OF INTERNAL MEDICINE
(2022)
Article
Surgery
Josh Bleicher, Sean M. Stokes, Benjamin S. Brooke, Robert E. Glasgow, Lyen C. Huang
Summary: This study found a weak correlation between discharge prescriptions and inpatient opioid use after surgery, leading to overprescribing for many patients and underprescribing for others.
JOURNAL OF SURGICAL RESEARCH
(2021)
Article
Surgery
Hallbera Gudmundsdottir, Daniel S. Ubl, Kathleen J. Yost, Halena M. Gazelka, Elizabeth B. Habermann, Cornelius A. Thiels
Summary: The objective of this study was to compare patient-reported outcomes before and after the implementation of evidence-based, procedure-specific opioid prescribing guidelines. The study found that although the guidelines successfully reduced opioid prescribing without increasing refill rates, there was still a reluctance to prescribe no opioids after surgery. Rating: 8 out of 10.
Article
Anesthesiology
Lisa K. Sharp, Pooja Solanki, Taylor Boyer, Amanda Vivo, Ibuola Kale, Ashley M. Hughes, Gretchen Gibson, M. Marianne Jurasic, Charlesnika T. Evans, Katie J. Suda
Summary: The U.S. Department of Veterans Affairs provides dental care to veterans and has implemented opioid risk mitigation strategies. This study aimed to explore the barriers and facilitators of opioid decision making among VA dentists. Interviews were conducted with dentists from high and low opioid prescription facilities, and the results identified potential intervention targets for continued risk mitigation efforts.
Article
Surgery
Ryan Howard, Craig S. Brown, Yen-Ling Lai, Vidhya Gunaseelan, Chad M. Brummett, Michael Englesbe, Jennifer Waljee, Mark C. Bicket
Summary: This study aimed to evaluate the association between postoperative opioid prescribing and new persistent opioid use. The results showed that the quantity of opioids prescribed after surgery was associated with new persistent opioid use, indicating that excessive prescribing increases the risk of long-term opioid use.
Article
Surgery
Jennifer M. Burg, Alyssa A. Mazurek, Alexander A. Brescia, Jarred R. Mondonedo, Andrew C. Chang, Jules Lin, William R. Lynch, Mark B. Orringer, Rishindra M. Reddy, Kiran H. Lagisetty
Summary: This study defined institutional opioid prescribing patterns, established prescribing guidelines, and evaluated the adherence to and effectiveness of these guidelines in association with opioid prescribing after hiatal hernia repair (HHR). The results showed that median prescription amount decreased by 54% for open and 43% laparoscopic repair after guideline implementation, with no detectable change in the overall refill rate.
JOURNAL OF SURGICAL RESEARCH
(2023)
Article
Health Care Sciences & Services
Jennifer J. Carroll, Phoebe A. Cushman, Marlene C. Lira, Jonathan A. Colasanti, Carlos del Rio, Karen E. Lasser, Victoria Parker, Payel J. Roy, Jeffrey H. Samet, Jane M. Liebschutz
Summary: This study explores the barriers, facilitators, and issues related to the wider implementation of a multi-faceted intervention for promoting guideline-adherent long-term opioid therapy in primary care settings. The intervention was generally well-received, with most participants valuing the didactic and team-based elements. Proximity to expertise, availability of behavioral health care, and support from a Nurse Care Manager were identified as facilitators of adopting new prescribing practices. However, concerns were raised about the intervention's appropriateness in specific clinical environments and its long-term sustainability.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2023)
Editorial Material
Multidisciplinary Sciences
Elena Garralda, Scott A. Laurie, Lesley Seymour, Elisabeth G. E. de Vries
Summary: Early detection of immunotherapy-induced tumor response is crucial, but therapy-induced pseudoprogression can make it complicated. A consensus guideline called iRECIST, a modification of RECIST version 1.1, was developed. This article explores the next steps required to test its validity and proposes novel approaches for response criteria.
NATURE COMMUNICATIONS
(2023)
Article
Surgery
Hoyune E. Cho, Hsou-Mei Hu, Vidhya Gunaseelan, Jung-Sheng Chen, Michael J. Englesbe, Kevin C. Chung, Jennifer F. Waljee
Summary: The study examined the correlation between aspects of surgical intensity and postoperative opioid prescribing, finding that as surgical intensity increased, both the initial opioid prescription and refill rates also increased. This suggests that aspects of surgical intensity could serve as a guide for procedures lacking guidelines based on patient-reported outcomes.
Article
Anesthesiology
Afton L. Hassett, Jennifer Pierce, Jenna Goesling, Laura Fritsch, Rishi R. Bakshi, David J. Kohns, Chad M. Brummett
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2020)
Article
Immunology
David C. Cron, Monica A. Tincopa, Jay S. Lee, Akbar K. Waljee, Ali Hammoud, Chad M. Brummett, Jennifer F. Waljee, Michael J. Englesbe, Christopher J. Sonnenday
Summary: Prescription opioid use is common before and after liver transplant, with intermittent and chronic use largely persisting, and a small development of new chronic use posttransplant. Pretransplant opioid use is a risk factor for persistent or increased posttransplant opioid use, while having hepatobiliary malignancy is protective. Improving pain management and optimizing opioid use before and after liver transplant is critical to minimize the morbidity of long-term opioid use.
Article
Surgery
Lauren M. McGee, Ajay Kolli, Calista M. Harbaugh, Ryan A. Howard, Michael J. Englesbe, Chad M. Brummett, Jennifer F. Waljee, Samir K. Gadepalli
JOURNAL OF SURGICAL RESEARCH
(2020)
Article
Anesthesiology
Jenna McAfee, Kevin F. Boehnke, Stephanie M. Moser, Chad M. Brummett, Jennifer F. Waljee, Erin E. Bonar
Summary: Despite the low prevalence of cannabis use in this surgical population, cannabis users reported higher clinical pain, poorer quality of life indicators, and more opioid misuse before and after surgery. However, both cannabis users and non-cannabis users showed improvement in most domains at 3 and 6 months post surgery, with no differences in surgical outcomes between the two groups at the 6-month mark.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2021)
Article
Clinical Neurology
Lara Massie, Vidhya Gunaseelan, Jennifer Waljee, Chad Brummett, Jason M. Schwalb
Summary: Surgeons can prescribe lower amounts of opioids after elective surgery for degenerative spinal disease for opioid-naive patients without concern of increased need for refills.
Article
Surgery
Deborah S. Keller, Brooke C. Kenney, Calista M. Harbaugh, Jennifer F. Waljee, Chad M. Brummett
Summary: Opioids are commonly prescribed for ambulatory anorectal procedures, with over 2% of patients developing new persistent opioid use. Despite small reductions in prescribing rates, there has been little change in the amount of opioids prescribed.
Article
Multidisciplinary Sciences
Jonas B. Nielsen, Oren Rom, Ida Surakka, Sarah E. Graham, Wei Zhou, Tanmoy Roychowdhury, Lars G. Fritsche, Sarah A. Gagliano Taliun, Carlo Sidore, Yuhao Liu, Maiken E. Gabrielsen, Anne Heidi Skogholt, Brooke Wolford, William Overton, Ying Zhao, Jin Chen, He Zhang, Whitney E. Hornsby, Akua Acheampong, Austen Grooms, Amanda Schaefer, Gregory J. M. Zajac, Luis Villacorta, Jifeng Zhang, Ben Brumpton, Mari Loset, Vivek Rai, Pia R. Lundegaard, Morten S. Olesen, Kent D. Taylor, Nicholette D. Palmer, Yii-Der Chen, Seung H. Choi, Steven A. Lubitz, Patrick T. Ellinor, Kathleen C. Barnes, Michelle Daya, Nicholas Rafaels, Scott T. Weiss, Jessica Lasky-Su, Russell P. Tracy, Ramachandran S. Vasan, L. Adrienne Cupples, Rasika A. Mathias, Lisa R. Yanek, Lewis C. Becker, Patricia A. Peyser, Lawrence F. Bielak, Jennifer A. Smith, Stella Aslibekyan, Bertha A. Hidalgo, Donna K. Arnett, Marguerite R. Irvin, James G. Wilson, Solomon K. Musani, Adolfo Correa, Stephen S. Rich, Xiuqing Guo, Jerome I. Rotter, Barbara A. Konkle, Jill M. Johnsen, Allison E. Ashley-Koch, Marilyn J. Telen, Vivien A. Sheehan, John Blangero, Joanne E. Curran, Juan M. Peralta, Courtney Montgomery, Wayne H-H Sheu, Ren-Hua Chung, Karen Schwander, Seyed M. Nouraie, Victor R. Gordeuk, Yingze Zhang, Charles Kooperberg, Alexander P. Reiner, Rebecca D. Jackson, Eugene R. Bleecker, Deborah A. Meyers, Xingnan Li, Sayantan Das, Ketian Yu, Jonathon LeFaive, Albert Smith, Tom Blackwell, Daniel Taliun, Sebastian Zollner, Lukas Forer, Sebastian Schoenherr, Christian Fuchsberger, Anita Pandit, Matthew Zawistowski, Sachin Kheterpal, Chad M. Brummett, Pradeep Natarajan, David Schlessinger, Seunggeun Lee, Hyun Min Kang, Francesco Cucca, Oddgeir L. Holmen, Bjorn O. Asvold, Michael Boehnke, Sekar Kathiresan, Goncalo R. Abecasis, Y. Eugene Chen, Cristen J. Willer, Kristian Hveem
NATURE COMMUNICATIONS
(2020)
Article
Surgery
Brian T. T. Fry, Ryan A. A. Howard, Vidhya Gunaseelan, Jay S. S. Lee, Jennifer F. F. Waljee, Michael J. J. Englesbe, Joceline V. V. Vu
Summary: In a large cohort of patients undergoing common surgical procedures, there was no significant association between opioid prescription size at discharge after surgery and patient satisfaction. This suggests that surgeons can provide smaller opioid prescriptions postoperatively without diminishing patient satisfaction.
Article
Obstetrics & Gynecology
Sawsan As-Sanie, Sara R. Till, Andrew D. Schrepf, Kendall C. Griffith, Alex Tsodikov, Stacey A. Missmer, Daniel J. Clauw, Chad M. Brummett
Summary: While most women with chronic pelvic pain experience significant pain relief following hysterectomy, higher levels of centralized pain before the surgery are a strong predictor of persistent pelvic pain in the long term.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2021)
Review
Anesthesiology
Daniel B. Larach, Jennifer M. Hah, Chad M. Brummett
Summary: This article summarizes current evidence on perioperative opioid prescription fulfillment and use, and discusses the role of personalized anesthesia care in mitigating opioid-related harms without compromising analgesia.
Article
Oncology
Jay S. Lee, Ciara M. Kelly, Edmund K. Bartlett
Summary: Pelvic sarcomas are rare tumors divided into soft tissue sarcomas and bone sarcomas. Multidisciplinary treatment at an experienced center is essential, and management is determined by histologic type and grade.
Letter
Anesthesiology
Jennifer Pierce, Afton Hassett, Jill R. Schneiderhan, Jude Divers, Chad M. Brummett, Jenna McAfee
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2021)
Article
Oncology
Nicholas W. Eyrich, Kenneth R. Sloss, Ryan A. Howard, Michael P. Klueh, Michael J. Englesbe, Jennifer F. Waljee, Chad M. Brummett, Michael S. Sabel, Lesly A. Dossett, Jay S. Lee
Summary: The study found that opioid prescribing exceeds consumption following common surgical oncology procedures. While most patients received education on taking opioids, few received instructions on proper disposal, leading to a high percentage of unused opioids.
JOURNAL OF SURGICAL ONCOLOGY
(2021)
