Food-grade TiO2 is trapped by intestinal mucus in vitro but does not impair mucin O-glycosylation and short-chain fatty acid synthesis in vivo: implications for gut barrier protection

Toxicity of Food-Grade TiO2 to Commensal Intestinal and Transient Food-Borne Bacteria: New Insights Using Nano-SIMS and Synchrotron UV Fluorescence Imaging

(2018) Joanna M. Radziwill-Bienkowska et al.   Frontiers in Microbiology

Effects of environmental pollutants on gut microbiota

(2017) Yuanxiang Jin et al.   ENVIRONMENTAL POLLUTION

Mucus organisation is shaped by colonic content; a new view

(2017) J. B. J. Kamphuis et al.   Scientific Reports

Food-grade TiO2 impairs intestinal and systemic immune homeostasis, initiates preneoplastic lesions and promotes aberrant crypt development in the rat colon

(2017) Sarah Bettini et al.   Scientific Reports

New Insight into Daptomycin Bioavailability and Localization in Staphylococcus aureus Biofilms by Dynamic Fluorescence Imaging

(2016) Rym Boudjemaa et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Oral uptake of nanoparticles: human relevance and the role of in vitro systems

(2016) Eleonore Fröhlich et al.   ARCHIVES OF TOXICOLOGY

Food-grade titanium dioxide exposure exacerbates tumor formation in colitis associated cancer model

(2016) Ismael M. Urrutia-Ortega et al.   FOOD AND CHEMICAL TOXICOLOGY

Titanium dioxide nanoparticles exacerbate DSS-induced colitis: role of the NLRP3 inflammasome

(2016) Pedro A Ruiz et al.   GUT

Titanium dioxide food additive (E171) induces ROS formation and genotoxicity: contribution of micro and nano-sized fractions

(2016) Héloïse Proquin et al.   MUTAGENESIS

New frontiers in nanotoxicology: Gut microbiota/microbiome-mediated effects of engineered nanomaterials

(2016) Antonio Pietroiusti et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The gut microbiota: a major player in the toxicity of environmental pollutants?

(2016) Sandrine P Claus et al.   npj Biofilms and Microbiomes

Oral exposure to environmental pollutant benzo[a]pyrene impacts the intestinal epithelium and induces gut microbial shifts in murine model

(2016) Céline Ribière et al.   Scientific Reports

Interactions between nano-TiO2 and the oral cavity: Impact of nanomaterial surface hydrophilicity/hydrophobicity

(2015) Birgit J. Teubl et al.   JOURNAL OF HAZARDOUS MATERIALS

Impact of anatase and rutile titanium dioxide nanoparticles on uptake carriers and efflux pumps in Caco-2 gut epithelial cells

(2015) M. Dorier et al.   Nanoscale

Effects of silver nanoparticles and ions on a co-culture model for the gastrointestinal epithelium

(2015) Anastasia Georgantzopoulou et al.   Particle and Fibre Toxicology

Human in vivo and in vitro studies on gastrointestinal absorption of titanium dioxide nanoparticles

(2015) Kate Jones et al.   TOXICOLOGY LETTERS

SIgA Binding to Mucosal Surfaces Is Mediated by Mucin-Mucin Interactions

(2015) Hannah L. Gibbins et al.   PLoS One

Stress disrupts intestinal mucus barrier in rats via mucin O-glycosylation shift: prevention by a probiotic treatment

(2014) Stéphanie Da Silva et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Food grade titanium dioxide disrupts intestinal brush border microvilli in vitro independent of sedimentation

(2014) James J. Faust et al.   CELL BIOLOGY AND TOXICOLOGY

Characterization of Food-Grade Titanium Dioxide: The Presence of Nanosized Particles

(2014) Yu Yang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

The buccal mucosa as a route for TiO2nanoparticle uptake

(2014) Birgit Johanna Teubl et al.   Nanotoxicology

Titanium dioxide nanoparticle impact and translocation through ex vivo, in vivo and in vitro gut epithelia

(2014) Emilie Brun et al.   Particle and Fibre Toxicology

Uptake of different crystal structures of TiO2 nanoparticles by Caco-2 intestinal cells

(2014) Constantinos Gitrowski et al.   TOXICOLOGY LETTERS

Studies of mucus in mouse stomach, small intestine, and colon. I. Gastrointestinal mucus layers have different properties depending on location as well as over the Peyer's patches

(2013) Anna Ermund et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Glycobiome: Bacteria and mucus at the epithelial interface

(2013) Janneke P. Ouwerkerk et al.   BEST PRACTICE & RESEARCH IN CLINICAL GASTROENTEROLOGY

Bacteroides thetaiotaomicron and Faecalibacterium prausnitzii influence the production of mucus glycans and the development of goblet cells in the colonic epithelium of a gnotobiotic model rodent

(2013) Laura Wrzosek et al.   BMC BIOLOGY

Structural basis for adaptation of lactobacilli to gastrointestinal mucus

(2013) Sabrina Etzold et al.   ENVIRONMENTAL MICROBIOLOGY

Virulent Shigella flexneri Affects Secretion, Expression, and Glycosylation of Gel-Forming Mucins in Mucus-Producing Cells

(2013) Brice Sperandio et al.   INFECTION AND IMMUNITY

The gastrointestinal mucus system in health and disease

(2013) Malin E. V. Johansson et al.   Nature Reviews Gastroenterology & Hepatology

The abundance and variety of carbohydrate-active enzymes in the human gut microbiota

(2013) Abdessamad El Kaoutari et al.   NATURE REVIEWS MICROBIOLOGY

Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity

(2013) A. Everard et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinctive Toxicity of TiO2 Rutile/Anatase Mixed Phase Nanoparticles on Caco-2 Cells

(2012) Kirsten Gerloff et al.   CHEMICAL RESEARCH IN TOXICOLOGY

TiO2 nanoparticles suppress Escherichia coli cell division in the absence of UV irradiation in acidic conditions

(2012) Lyudmila V. Zhukova et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Titanium Dioxide Nanoparticles in Food and Personal Care Products

(2012) Alex Weir et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Primocolonization is associated with colonic epithelial maturation during conventionalization

(2012) Julie Tomas et al.   FASEB JOURNAL

Almost all human gastric mucin O-glycans harbor blood group A, B or H antigens and are potential binding sites for Helicobacter pylori

(2012) Yannick Rossez et al.   GLYCOBIOLOGY

Microbes inside—from diversity to function: the case of Akkermansia

(2012) Clara Belzer et al.   ISME Journal

Butyrate-producing Clostridium cluster XIVa species specifically colonize mucins in an in vitro gut model

(2012) Pieter Van den Abbeele et al.   ISME Journal

Design of a Specific Colonic Mucus Marker Using a Human Commensal Bacterium Cell Surface Domain

(2012) Yves-Marie Coïc et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Influence of simulated gastrointestinal conditions on particle-induced cytotoxicity and interleukin-8 regulation in differentiated and undifferentiated Caco-2 cells

(2012) Kirsten Gerloff et al.   Nanotoxicology

Functional interactions between the gut microbiota and host metabolism

(2012) Valentina Tremaroli et al.   NATURE

Lactobacillaceae and Cell Adhesion: Genomic and Functional Screening

(2012) Williams Turpin et al.   PLoS One

Engineered ZnO and TiO2 nanoparticles induce oxidative stress and DNA damage leading to reduced viability of Escherichia coli

(2011) Ashutosh Kumar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mucin Secretion Induced by Titanium Dioxide Nanoparticles

(2011) Eric Y. T. Chen et al.   PLoS One

Microbial adhesins to gastrointestinal mucus

(2011) Nathalie Juge   TRENDS IN MICROBIOLOGY

Mucolytic Bacteria With Increased Prevalence in IBD Mucosa Augment In Vitro Utilization of Mucin by Other Bacteria

(2010) Chin Wen Png et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Mucosal Adhesion Properties of the Probiotic Lactobacillus rhamnosus GG SpaCBA and SpaFED Pilin Subunits

(2010) I. von Ossowski et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The damage of outer membrane of Escherichia coli in the presence of TiO2 combined with UV light

(2010) Peng Liu et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Strain-specific diversity of mucus-binding proteins in the adhesion and aggregation properties of Lactobacillus reuteri

(2010) D. A. MacKenzie et al.   MICROBIOLOGY-SGM

Ultrasonic dispersion of nanoparticles for environmental, health and safety assessment – issues and recommendations

(2010) Julian S. Taurozzi et al.   Nanotoxicology

The two mucus layers of colon are organized by the MUC2 mucin, whereas the outer layer is a legislator of host-microbial interactions

(2010) M. E. V. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histochemical study of intestinal mucins after administration of silver nanoparticles in Sprague–Dawley rats

(2009) Gil Nam Jeong et al.   ARCHIVES OF TOXICOLOGY

The regulation of intestinal mucin MUC2 expression by short-chain fatty acids: implications for epithelial protection

(2009) Nanda Burger-van Paassen et al.   BIOCHEMICAL JOURNAL

Toxicity and cellular responses of intestinal cells exposed to titanium dioxide

(2009) Brian A. Koeneman et al.   CELL BIOLOGY AND TOXICOLOGY

Increased induction of apoptosis by Propionibacterium freudenreichii TL133 in colonic mucosal crypts of human microbiota-associated rats treated with 1,2-dimethylhydrazine

(2008) Annaïg Lan et al.   BRITISH JOURNAL OF NUTRITION

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

(2008) M. E. V. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA