Bergenin loaded gum xanthan stabilized silver nanoparticles suppress synovial inflammation through modulation of the immune response and oxidative stress in adjuvant induced arthritic rats

Molecular mechanisms of action of anti-TNF-α agents – Comparison among therapeutic TNF-α antagonists

(2018) Hiroki Mitoma et al.   CYTOKINE

Gum acacia stabilized silver nanoparticles based nano-cargo for enhanced anti-arthritic potentials of hesperidin in adjuvant induced arthritic rats

(2018) Komal Rao et al.   Artificial Cells Nanomedicine and Biotechnology

M1 and M2 Monocytes in Rheumatoid Arthritis: A Contribution of Imbalance of M1/M2 Monocytes to Osteoclastogenesis

(2018) Shoichi Fukui et al.   Frontiers in Immunology

N-(2-Hydroxyphenyl)acetamide: a Novel Suppressor of RANK/RANKL Pathway in Collagen-Induced Arthritis Model in Rats

(2017) Anum Gul et al.   INFLAMMATION

Is macrophage polarization important in rheumatoid arthritis?

(2017) Yang Wang et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

A Novel Highly Bioavailable Curcumin Formulation Improves Symptoms and Diagnostic Indicators in Rheumatoid Arthritis Patients: A Randomized, Double-Blind, Placebo-Controlled, Two-Dose, Three-Arm, and Parallel-Group Study

(2017) Augustine Amalraj et al.   JOURNAL OF MEDICINAL FOOD

Advancement in contemporary diagnostic and therapeutic approaches for rheumatoid arthritis

(2016) L. Dinesh Kumar et al.   BIOMEDICINE & PHARMACOTHERAPY

Understanding the role of cytokines in the pathogenesis of rheumatoid arthritis

(2016) Somaiya Mateen et al.   CLINICA CHIMICA ACTA

Redox signaling in rheumatoid arthritis and the preventive role of polyphenols

(2016) Somaiya Mateen et al.   CLINICA CHIMICA ACTA

Sugar-based novel niosomal nanocarrier system for enhanced oral bioavailability of levofloxacin

(2016) Muhammad Imran et al.   DRUG DELIVERY

Development of a biocompatible creatinine-based niosomal delivery system for enhanced oral bioavailability of clarithromycin

(2016) Shafi Ullah et al.   DRUG DELIVERY

CP-25, a novel compound, protects against autoimmune arthritis by modulating immune mediators of inflammation and bone damage

(2016) Yan Chang et al.   Scientific Reports

Increased Reactive Oxygen Species Formation and Oxidative Stress in Rheumatoid Arthritis

(2016) Somaiya Mateen et al.   PLoS One

IL-6 inhibitors for treatment of rheumatoid arthritis: past, present, and future

(2015) Go Woon Kim et al.   ARCHIVES OF PHARMACAL RESEARCH

Diversity, pharmacology and synthesis of bergenin and its derivatives: Potential materials for therapeutic usages

(2015) Gan B. Bajracharya   FITOTERAPIA

Cytokines in rheumatoid arthritis — shaping the immunological landscape

(2015) Iain B. McInnes et al.   Nature Reviews Rheumatology

Xanthan gum stabilized gold nanoparticles: Characterization, biocompatibility, stability and cytotoxicity

(2014) Deep Pooja et al.   CARBOHYDRATE POLYMERS

Bergenin Plays an Anti-Inflammatory Role via the Modulation of MAPK and NF-κB Signaling Pathways in a Mouse Model of LPS-Induced Mastitis

(2014) Xue-jiao Gao et al.   INFLAMMATION

Pyrano-isochromanones as IL-6 Inhibitors: Synthesis, in Vitro and in Vivo Antiarthritic Activity

(2014) Shreyans K. Jain et al.   JOURNAL OF MEDICINAL CHEMISTRY

N-(2-hydroxy phenyl) acetamide: a novel suppressor of Toll-like receptors (TLR-2 and TLR-4) in adjuvant-induced arthritic rats

(2014) Kahkashan Perveen et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Silver Nanoscale Antisense Drug Delivery System for Photoactivated Gene Silencing

(2013) Paige K. Brown et al.   ACS Nano

Acute Liver Injury due to Flavocoxid (Limbrel), a Medical Food for Osteoarthritis

(2013) Naga Chalasani   ANNALS OF INTERNAL MEDICINE

Green synthesis of silver nanoparticles using cellulose extracted from an aquatic weed; water hyacinth

(2013) Tanki Mochochoko et al.   CARBOHYDRATE POLYMERS

Anti-inflammatory and apoptotic effects of the polyphenol curcumin on human fibroblast-like synoviocytes

(2013) Burkhard Kloesch et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Toll-like receptors as therapeutic targets for autoimmune connective tissue diseases

(2013) Jing Li et al.   PHARMACOLOGY & THERAPEUTICS

Understanding the stability of silver nanoparticles bio-fabricated using Acacia arabica (Babool gum) and its hostile effect on microorganisms

(2013) Mukeshchand Thakur et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Synthesis of new bergenin derivatives as potent inhibitors of inflammatory mediators NO and TNF-α

(2012) Muhammad Raza Shah et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The anti-arthritic and anti-oxidative effect of NBD (6-nitro-1,3-benzodioxane) in adjuvant-induced arthritis (AIA) in rats

(2012) Syed Uzair Ali Shah et al.   INFLAMMATION RESEARCH

A Randomized, Pilot Study to Assess the Efficacy and Safety of Curcumin in Patients with Active Rheumatoid Arthritis

(2012) Binu Chandran et al.   PHYTOTHERAPY RESEARCH

Hesperidin inhibits collagen-induced arthritis possibly through suppression of free radical load and reduction in neutrophil activation and infiltration

(2012) Sadiq Umar et al.   RHEUMATOLOGY INTERNATIONAL

Formulation and evaluation of novel coated floating tablets of bergenin and cetirizine dihydrochloride for gastric delivery

(2011) Shuang He et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

IL-1  and TNF -initiated IL-6-STAT3 pathway is critical in mediating inflammatory cytokines and RANKL expression in inflammatory arthritis

(2011) T. Mori et al.   INTERNATIONAL IMMUNOLOGY

Antinociceptive Properties of Bergenin

(2011) Cristiane Metzker de Oliveira et al.   JOURNAL OF NATURAL PRODUCTS

Nanoparticles: a boon to drug delivery, therapeutics, diagnostics and imaging

(2011) Suphiya Parveen et al.   Nanomedicine-Nanotechnology Biology and Medicine

Progress in understanding adjuvant immunotoxicity mechanisms

(2011) Alexander Batista-Duharte et al.   TOXICOLOGY LETTERS

Efficacy and safety of flavocoxid, a novel therapeutic, compared with naproxen: a randomized multicenter controlled trial in subjects with osteoarthritis of the knee

(2010) Robert M. Levy et al.   ADVANCES IN THERAPY

Modified gums: Approaches and applications in drug delivery

(2010) Vikas Rana et al.   CARBOHYDRATE POLYMERS

Preparation, characterization and in vivo evaluation of bergenin-phospholipid complex

(2009) Xuan Qin et al.   ACTA PHARMACOLOGICA SINICA

Synergism of toll-like receptor 2 (TLR2), TLR4, and TLR6 ligation on the production of tumor necrosis factor (TNF)-α in a spontaneous arthritis animal model of interleukin (IL)-1 receptor antagonist-deficient mice

(2009) Young Ok Jung et al.   IMMUNOLOGY LETTERS

The development of novel therapies for rheumatoid arthritis

(2008) Ling-dong Quan et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

A study on antioxidant, free radical scavenging, anti-inflammatory and hepatoprotective actions of Aegiceras corniculatum (stem) extracts

(2008) Talat Roome et al.   JOURNAL OF ETHNOPHARMACOLOGY

Antioxidant activity of (+)-bergenin—a phytoconstituent isolated from the bark of Sacoglottis uchi Huber (Humireaceae)

(2008) Heitor A. De Abreu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY