Early Growth Response 1 (Egr1) Is a Transcriptional Activator of NOX4 in Oxidative Stress of Diabetic Kidney Disease

Epigallocatechin gallate upregulates NRF2 to prevent diabetic nephropathy via disabling KEAP1

(2017) Weixia Sun et al.   FREE RADICAL BIOLOGY AND MEDICINE

Psoriasis-like inflammation leads to renal dysfunction via upregulation of NADPH oxidases and inducible nitric oxide synthase

(2017) Naif O. Al-Harbi et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Diabetes and Kidney Disease: Role of Oxidative Stress

(2016) Jay C. Jha et al.   ANTIOXIDANTS & REDOX SIGNALING

C66 ameliorates diabetic nephropathy in mice by both upregulating NRF2 function via increase in miR-200a and inhibiting miR-21

(2016) Hao Wu et al.   DIABETOLOGIA

Egr-1 deficiency protects from renal inflammation and fibrosis

(2016) Li-Chun Ho et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Trends in Chronic Kidney Disease in China

(2016) Luxia Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE

Transcription Factor Egr1 is Involved in High Glucose-Induced Proliferation and Fibrosis in Rat Glomerular Mesangial Cells

(2015) Dan Wang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Metabolomics Reveals a Key Role for Fumarate in Mediating the Effects of NADPH Oxidase 4 in Diabetic Kidney Disease

(2015) Y.-H. You et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Mammalian Target of Rapamycin Regulates Nox4-Mediated Podocyte Depletion in Diabetic Renal Injury

(2013) Assaad A. Eid et al.   DIABETES

Reversibility of Structural and Functional Damage in a Model of Advanced Diabetic Nephropathy

(2013) W. Pichaiwong et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Loss of Klotho Contributes to Kidney Injury by Derepression of Wnt/ -Catenin Signaling

(2013) L. Zhou et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

For an Influenza Vaccine, Are Two Bs Better Than One?

(2013) Lindsey R. Baden   NEW ENGLAND JOURNAL OF MEDICINE

Inhibition of matrix metalloproteinase-2 by halofuginone is mediated by the Egr1 transcription factor

(2012) Eyal Zcharia et al.   ANTI-CANCER DRUGS

Heparanase Is Essential for the Development of Diabetic Nephropathy in Mice

(2011) N. Gil et al.   DIABETES

Protective effect of apocynin, a NADPH-oxidase inhibitor, against contrast-induced nephropathy in the diabetic rats: A comparison with n-acetylcysteine

(2011) Akbar Ahmad et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Early growth response transcription factors: Key mediators of fibrosis and novel targets for anti-fibrotic therapy

(2011) Swati Bhattacharyya et al.   MATRIX BIOLOGY

Egr-1 Induces a Profibrotic Injury/Repair Gene Program Associated with Systemic Sclerosis

(2011) Swati Bhattacharyya et al.   PLoS One

The molecular mediators of type 2 epithelial to mesenchymal transition (EMT) and their role in renal pathophysiology

(2010) Wendy C. Burns et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

The NADPH Oxidase Subunit NOX4 Is a New Target Gene of the Hypoxia-inducible Factor-1

(2010) Isabel Diebold et al.   MOLECULAR BIOLOGY OF THE CELL

NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury

(2009) Louise Hecker et al.   NATURE MEDICINE

Scleroderma

(2009) Armando Gabrielli et al.   NEW ENGLAND JOURNAL OF MEDICINE

Subcellular localization of Nox4 and regulation in diabetes

(2009) K. Block et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Oxidant and Redox Signaling in Vascular Oxygen Sensing: Implications for Systemic and Pulmonary Hypertension

(2008) Sachin A. Gupte et al.   ANTIOXIDANTS & REDOX SIGNALING