Article
Radiology, Nuclear Medicine & Medical Imaging
Shi-hai Zhao, Wei-feng Guo, Zhi-feng Yao, Shan Yang, Hong Yun, Yin-yin Chen, Tong-tong Han, Xiao-yue Zhou, Cai-xia Fu, Meng-su Zeng, Chen-guang Li, Cui-zhen Pan, Hang Jin
Summary: In this study, a fully automated pixel-wise post-processing framework was used to evaluate quantitative cardiovascular magnetic resonance myocardial perfusion imaging (CMR-MPI). The study aimed to assess the additional value of coronary magnetic resonance angiography (CMRA) in the diagnostic performance of fully automated pixel-wise quantitative CMR-MPI for detecting hemodynamically significant coronary artery disease (CAD). The results showed that the fully automated pixel-wise quantitative CMR-MPI can accurately detect hemodynamically significant CAD, but the integration of CMRA did not provide significantly additive value.
EUROPEAN RADIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Gilles Rioufol, Francois Derimay, Francois Roubille, Thibault Perret, Pascal Motreff, Denis Angoulvant, Yves Cottin, Ludovic Meunier, Laura Cetran, Guillaume Cayla, Brahim Harbaoui, Jean-Yves Wiedemann, Eric Van Belle, Christophe Pouillot, Nathalie Noirclerc, Jean-Francois Morelle, Francois-Xavier Soto, Christophe Caussin, Bernard Bertrand, Thierry Lefevre, Patrick Dupouy, Pierre-Francois Lesault, Franck Albert, Olivier Barthelemy, Rene Koning, Laurent Leborgne, Pierre Barnay, Philippe Chapon, Sebastien Armero, Antoine Lafont, Christophe Piot, Camille Amaz, Bernadette Vaz, Lakhdar Benyahya, Yvonne Varillon, Michel Ovize, Nathan Mewton, Gerard Finet
Summary: The FUTURE trial investigated whether a treatment strategy based on FFR was superior to a traditional strategy in the treatment of multivessel CAD, and found no significant difference in rates of major adverse cardiac events or death at 1-year follow-up between the two groups.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Multidisciplinary Sciences
Kai Nogami, Masahiro Hoshino, Yoshihisa Kanaji, Tomoyo Sugiyama, Toru Misawa, Masahiro Hada, Masao Yamaguchi, Tatsuhiro Nagamine, Yun Teng, Hiroki Ueno, Kazuki Matsuda, Kodai Sayama, Tsunekazu Kakuta
Summary: This study assessed the prevalence and prognostic significance of unrecognized myocardial infarction (UMI) before elective percutaneous coronary intervention (PCI) using delayed-enhancement cardiac magnetic resonance (DE-CMR). The results showed that UMI was significantly associated with sex, diabetes mellitus, left ventricular ejection fraction, SYNTAX score, and fractional flow reserve in the target vessels. UMI was found to be an independent predictor of major adverse cardiac events (MACE) and was associated with a higher risk of MACE after successful PCI.
SCIENTIFIC REPORTS
(2022)
Review
Medicine, General & Internal
Anna Baritussio, Alessandra Scatteia, Santo Dellegrottaglie, Chiara Bucciarelli-Ducci
Summary: Cardiovascular magnetic resonance is a valuable imaging technique with clear applications in managing patients with coronary artery disease, from diagnosis to prognosis.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Satoshi Nakamura, Masaki Ishida, Kei Nakata, Masafumi Takafuji, Shiro Nakamori, Tairo Kurita, Haruno Ito, Kaoru Dohi, Hajime Sakuma
Summary: This study investigated the complementary prognostic value of stress myocardial perfusion imaging and global coronary flow reserve (CFR) in long-term follow-up of patients with suspected or known coronary artery disease (CAD). The results showed that stress perfusion imaging and global CFR provided complementary prognostic value for predicting cardiovascular events.
JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE
(2023)
Article
Cardiac & Cardiovascular Systems
Toshiki Tanigaki, Shingo Kato, Mai Azuma, Masanori Ito, Nobuyuki Horita, Daisuke Utsunomiya
Summary: CMR-derived CFR is a promising method for evaluating stable CAD, cardiomyopathy, and risk stratification in CAD. Its clinical value has been confirmed through a meta-analysis, which showed that decreased CFR is associated with a higher occurrence of MACE in patients with stable CAD.
JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE
(2023)
Article
Physics, Multidisciplinary
Joao R. Alves, Lucas A. Berg, Evandro D. Gaio, Bernardo M. Rocha, Rafael A. B. de Queiroz, Rodrigo W. dos Santos
Summary: This paper presents a novel hybrid approach for modeling cardiac perfusion by combining a discrete model of the coronary arterial tree with a continuous flow model of the myocardium. The model accurately represents the blood flow and contrast agent dynamics in the coronary arterial tree and myocardial tissue. The integration of data from CT scans and MRI scans enhances clinical understanding and treatment strategies for managing cardiovascular disease.
Article
Cardiac & Cardiovascular Systems
Louise A. E. Brown, Gaurav S. Gulsin, Sebastian C. Onciul, David A. Broadbent, Jian L. Yeo, Alice L. Wood, Christopher E. D. Saunderson, Arka Das, Nicholas Jex, Amrit Chowdhary, Sharmaine Thirunavukarasu, Noor Sharrack, Kristopher D. Knott, Eylem Levelt, Peter P. Swoboda, Hui Xue, John P. Greenwood, James C. Moon, David Adlam, Gerry P. McCann, Peter Kellman, Sven Plein
Summary: This study aimed to establish sex- and age-specific normal values for myocardial blood flow (MBF) in healthy volunteers. The results showed differences in MBF between males and females, and a decrease in MBF and myocardial perfusion reserve with advancing age.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Klas Berggren, Daniel Ryd, Einar Heiberg, Anthony H. Aletras, Erik Hedstrom
Summary: By combining phase-encoding undersampling with super-resolution neural networks, high-resolution fetal cine cardiac MR images can be achieved with shorter acquisition time, potentially improving the success rate of fetal MR imaging while maintaining image quality.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Maurice Pradella, Michael B. Scott, Muhammad Omer, Seth K. Hill, Lisette Lockhart, Xin Yi, Alborz Amir-Khalili, Alireza Sojoudi, Bradley D. Allen, Ryan Avery, Michael Markl
Summary: DL analysis for automated vessel contour delineation and flow quantification in 2D-CINE-PC-MRI showed excellent performance with an accuracy rate of 93.4% compared to manual analysis and corrected semi-automated analysis.
EUROPEAN RADIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Martina C. de Knegt, Alexia Rossi, Steffen E. Petersen, Andrew Wragg, Ruhaid Khurram, Mark Westwood, Bunny Saberwal, Anthony Mathur, Koen Nieman, Fabian Bamberg, Magnus T. Jensen, Francesca Pugliese
Summary: This study aimed to evaluate the diagnostic performance and incremental value of qualitative CMR perfusion and quantitative CT perfusion, when used in combination with CCTA, for the diagnosis of haemodynamically significant CAD. The results showed that visual CMR perfusion and relative CT-MBF outperformed visual CT perfusion, and combining these modalities with CCTA improved discrimination in diagnosing haemodynamically significant CAD.
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2021)
Article
Cardiac & Cardiovascular Systems
Haseeb Rahman, Cian M. Scannell, Ozan M. Demir, Matthew Ryan, Hannah McConkey, Howard Ellis, Pier Giorgio Masci, Divaka Perera, Amedeo Chiribiri
Summary: This study demonstrated that high-resolution cardiac magnetic resonance (CMR) has good accuracy in detecting coronary microvascular dysfunction (CMD) when analyzed quantitatively. Quantitative perfusion CMR plays an increasingly important role in the management of patients with angina and nonobstructive coronary artery disease (NOCAD).
JACC-CARDIOVASCULAR IMAGING
(2021)
Review
Cardiac & Cardiovascular Systems
Mihir A. Kelshiker, Henry Seligman, James P. Howard, Haseeb Rahman, Michael Foley, Alexandra N. Nowbar, Christopher A. Rajkumar, Matthew J. Shun-Shin, Yousif Ahmad, Sayan Sen, Rasha Al-Lamee, Ricardo Petraco
Summary: This meta-analysis aims to quantify the association between reduced coronary flow and all-cause mortality and major adverse cardiovascular events (MACE). The results show that abnormal coronary flow reserve (CFR) is associated with higher incidence of all-cause mortality and MACE. Each 0.1 unit reduction in CFR is associated with a proportional increase in mortality and MACE.
EUROPEAN HEART JOURNAL
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jakob Koefoed Tingsgaard, Martin Heyn Sorensen, Annemie Stege Bojer, Robert H. H. Anderson, David Andrew Broadbent, Sven Plein, Peter Gaede, Per Lav Madsen
Summary: This study aimed to compare myocardial blood flow (MBF) determined from coronary sinus blood flow (MBFCS) with that determined from dynamic contrast-enhanced imaging (MBFDCE) in a large cohort. The results showed that MBFCS had good repeatability but had a certain bias and relatively large limits of agreement compared to MBFDCE.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2023)
Article
Multidisciplinary Sciences
Amir Moussavi, Sophie Missbach, Claudia Serrano Ferrel, Hasti Ghasemipour, Kristin Koetz, Charis Drummer, Rudiger Behr, Wolfram-Hubertus Zimmermann, Susann Boretius
Summary: Real-Time (RT) cardiac MRI is a feasible alternative to standard cine MRI for assessing cardiac function in rhesus macaques, with consistent underestimations of functional parameters but high repeatability. Additionally, RT-MRI allows for analysis of cardio-respiratory coupling and reduces experimental effort, measurement time, risk, and burden for animals compared to cine MRI.
SCIENTIFIC REPORTS
(2021)
Editorial Material
Cardiac & Cardiovascular Systems
Junko Ishiura, Shiro Nakamori, Masaki Ishida, Hajime Sakuma, Kaoru Dohi
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2021)
Article
Cardiac & Cardiovascular Systems
Fay M. A. Nous, Tobias Geisler, Mariusz B. P. Kruk, Hatem Alkadhi, Kakuya Kitagawa, Rozemarijn Vliegenthart, Michaela M. Hell, Jorg Hausleiter, Patricia K. Nguyen, Ricardo P. J. Budde, Konstantin Nikolaou, Cezary Kepka, Robert Manka, Hajime Sakuma, Sachin B. Malik, Adriaan Coenen, Felix Zijlstra, Ernst Klotz, Pim van der Harst, Christoph Artzner, Admir Dedic, Francesca Pugliese, Fabian Bamberg, Koen Nieman
Summary: In this multicenter study, the combination of dynamic stress CT myocardial perfusion imaging (CT-MPI) with coronary CT angiography (CTA) showed incremental diagnostic value for the identification of hemodynamically significant coronary artery disease.
JACC-CARDIOVASCULAR IMAGING
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Junko Ishiura, Shiro Nakamori, Masaki Ishida, Kaoru Dohi
EUROPEAN HEART JOURNAL
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Cherry Kim, Chul Hwan Park, Do Yeon Kim, Jaehyung Cha, Bae Young Lee, Chan Ho Park, Eun-Ju Kang, Hyun Jung Koo, Kakuya Kitagawa, Min Jae Cha, Rungroj Krittayaphong, Sang Il Choi, Sanjaya Viswamitra, Sung Min Ko, Sung Mok Kim, Sung Ho Hwang, Nguyen Ngoc Trang, Whal Lee, Young Jin Kim, Jongmin Lee, Dong Hyun Yang
Summary: This study evaluated the effect of implementing the consensus statement on the reliability of cardiac MR with late gadolinium enhancement myocardial viability scoring. The results showed that the implementation of the consensus improved the interobserver agreement and reliability of the scoring.
KOREAN JOURNAL OF RADIOLOGY
(2022)
Article
Urology & Nephrology
Ayumi Omori, Kan Katayama, Ryosuke Saiki, Satoru Masui, Kei Suzuki, Yoshinori Kanii, Kayo Tsujimoto, Shiro Nakamori, Tairo Kurita, Tomohiro Murata, Takahiro Inoue, Kaoru Dohi
Summary: This case report describes a patient with Noonan syndrome presenting with macrohematuria and proteinuria due to Nutcracker syndrome with double inferior vena cava and von Willebrand disease type 1. Genetic analysis revealed vulnerability of the glomerular basement membrane leading to proteinuria in this patient.
Review
Cardiac & Cardiovascular Systems
Shiro Nakamori, Kaoru Dohi
Summary: Alterations in myocardial tissue play a crucial role in cardiac remodeling and the development of chronic heart failure. Early detection of these changes is of great diagnostic and prognostic significance. Cardiovascular magnetic resonance has emerged as the gold standard imaging technique for noninvasive characterization of myocardial tissue composition. T1 and T2 mapping are important techniques in clinical practice for myocardial tissue characterization.
JOURNAL OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Mizuki Ida, Shiro Nakamori, Shinya Yamamoto, Seimi Watanabe, Kyoko Imanaka-Yoshida, Masaki Ishida, Hajime Sakuma, Keiichi Yamanaka, Kaoru Dohi
Summary: In this article, we present a complex case of an 81-year-old female patient who experienced persistently high levels of troponin after immunotherapy and displayed amyloid deposition in the myocardium. However, histological examination revealed minimal T-lymphocyte infiltration and no myocyte necrosis, indicating transthyretin cardiac amyloidosis rather than immune checkpoint inhibitor myocarditis. This case highlights the importance of evaluating other causes of elevated troponin levels and the necessity of comprehensive histological and immunohistochemical examinations when cardiovascular magnetic resonance imaging is inconclusive.
Editorial Material
Cardiac & Cardiovascular Systems
Yumi Hirota, Shiro Nakamori, Kyoko Imanaka-Yoshida, Masaki Ishida, Toshiro Mizuno, Hajime Sakuma, Kaoru Dohi
CIRCULATION-CARDIOVASCULAR IMAGING
(2022)
Editorial Material
Cardiac & Cardiovascular Systems
Kazuma Yamaguchi, Mizuki Ida, Shiro Nakamori, Ryosuke Sugimoto, Kaoru Dohi
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Suguru Araki, Kakuya Kitagawa, Takanori Kokawa, Masafumi Takafuji, Satoshi Nakamura, Naoki Nagasawa, Hajime Sakuma
Summary: This study investigated radiation exposure and the utilization of dose-saving strategies for coronary computed tomography angiography (CTA) in hospitals in Mie Prefecture, Japan. The results showed that the radiation dose of coronary CTA was slightly higher than the standards in the Japan Diagnostic Reference Level (DRLs) 2020 report, but significantly higher than those reported in a previous international dose survey. It was also found that low tube potential and prospective scanning were underutilized in the study region, indicating the need for further optimization of radiation exposure from cardiac CT scans.
JAPANESE JOURNAL OF RADIOLOGY
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Shiro Nakamori, Naoki Fujimoto, Masaki Ishida, Masahiro Masuya, Kaoru Dohi
EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING
(2023)
Article
Cardiac & Cardiovascular Systems
Satoshi Nakamura, Masaki Ishida, Kei Nakata, Masafumi Takafuji, Shiro Nakamori, Tairo Kurita, Haruno Ito, Kaoru Dohi, Hajime Sakuma
Summary: This study investigated the complementary prognostic value of stress myocardial perfusion imaging and global coronary flow reserve (CFR) in long-term follow-up of patients with suspected or known coronary artery disease (CAD). The results showed that stress perfusion imaging and global CFR provided complementary prognostic value for predicting cardiovascular events.
JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE
(2023)
Meeting Abstract
Cardiac & Cardiovascular Systems
Mizuki Ida, Shiro Nakamori, Junko Ishiura, Rie Ito, Masaki Ishida, Naoki Fujimoto, Ryuji Okamoto, Kyoko Imanaka-Yoshida, Hajime Sakuma, Kaoru Dohi
Meeting Abstract
Cardiac & Cardiovascular Systems
Masaki Ishiyama, Naoki Fujimoto, Toru Sato, Taku Omori, Keishi Moriwaki, Emiyo Sugiura, Yoshito Ogihara, Shiro Nakamori, Tairo Kurita, Kaoru Dohi
Article
Cardiac & Cardiovascular Systems
Keishi Moriwaki, Naoki Fujimoto, Taku Omori, So Miyahara, Issei Kameda, Masaki Ishiyama, Emiyo Sugiura, Shiro Nakamori, Kaoru Dohi
Summary: The study demonstrated that isometric handgrip training has certain effects on the cardiovascular function of HFrEF and HFpEF patients, but the specific mechanism is still unclear. IHG exercise may increase LVESP and LVEDP without adverse effects on cardiac function or ventricular-arterial coupling.