Interplay Between Membrane Permeability and Enzymatic Barrier Leads to Antibiotic-Dependent Resistance in Klebsiella Pneumoniae

Activity of ceftolozane/tazobactam against surveillance and ‘problem’ Enterobacteriaceae, Pseudomonas aeruginosa and non-fermenters from the British Isles

(2017) David M. Livermore et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

High-level carbapenem-resistant OXA-48-producing Klebsiella pneumoniae with a novel OmpK36 variant and low-level, carbapenem-resistant, non-porin-deficient, OXA-181-producing Escherichia coli from Thailand

(2016) Kamonwan Lunha et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Treatment options for infections caused by carbapenem-resistantEnterobacteriaceae: can we apply “precision medicine” to antimicrobial chemotherapy?

(2016) Federico Perez et al.   EXPERT OPINION ON PHARMACOTHERAPY

Klebsiella pneumoniae Population Genomics and Antimicrobial-Resistant Clones

(2016) Kelly L. Wyres et al.   TRENDS IN MICROBIOLOGY

Step-Wise Increase in Tigecycline Resistance in Klebsiella pneumoniae Associated with Mutations in ramR, lon and rpsJ

(2016) Li Fang et al.   PLoS One

In VitroActivities of Ceftazidime-Avibactam, Aztreonam-Avibactam, and a Panel of Older and Contemporary Antimicrobial Agents against Carbapenemase-Producing Gram-Negative Bacilli

(2015) Shawn Vasoo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A single-day point-prevalence study of faecal carriers in long-term care hospitals in Madrid (Spain) depicts a complex clonal and polyclonal dissemination of carbapenemase-producing Enterobacteriaceae

(2015) Patricia Ruiz-Garbajosa et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Elucidation of the RamA Regulon in Klebsiella pneumoniae Reveals a Role in LPS Regulation

(2015) Shyamasree De Majumdar et al.   PLoS Pathogens

In Vivo Evolution of Bacterial Resistance in Two Cases of Enterobacter aerogenes Infections during Treatment with Imipenem

(2015) Nadège Philippe et al.   PLoS One

Expansion of ESBL-producing Klebsiella pneumoniae in hospitalized patients: A successful story of international clones (ST15, ST147, ST336) and epidemic plasmids (IncR, IncFII K )

(2014) Carla Rodrigues et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Differential contribution of AcrAB and OqxAB efflux pumps to multidrug resistance and virulence in Klebsiella pneumoniae

(2014) Suzanne Bialek-Davenet et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Incidence rates of carbapenemase-producing Enterobacteriaceae clinical isolates in France: a prospective nationwide study in 2011-12

(2014) J. Robert et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Elucidating the Regulon of Multidrug Resistance Regulator RarA in Klebsiella pneumoniae

(2013) Shyamasree De Majumdar et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Comparative Population Analysis of Klebsiella pneumoniae Strains with Extended-Spectrum β-Lactamases Colonizing Patients in Rehabilitation Centers in Four Countries

(2013) A. Baraniak et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Characterization of a Novel Pyranopyridine Inhibitor of the AcrAB Efflux Pump of Escherichia coli

(2013) Timothy J. Opperman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Carbapenem and cefoxitin resistance of Klebsiella pneumoniae strains associated with porin OmpK36 loss and DHA-1 β-lactamase production

(2013) Weifeng Shi et al.   BRAZILIAN JOURNAL OF MICROBIOLOGY

Long-term dissemination of acquired AmpC β-lactamases among Klebsiella spp. and Escherichia coli in Portuguese clinical settings

(2013) F. Freitas et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Intercontinental spread of OXA-48 beta-lactamase-producing Enterobacteriaceae over a 11-year period, 2001 to 2011

(2013) A Potron et al.   Eurosurveillance

Clinical relevance of the ESKAPE pathogens

(2013) Jack N Pendleton et al.   Expert Review of Anti-Infective Therapy

Genetic characterization of tigecycline resistance in clinical isolates of Enterobacter cloacae and Enterobacter aerogenes

(2013) M. Veleba et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

In vitro activity of temocillin against multidrug-resistant clinical isolates of Escherichia coli, Klebsiella spp. and Enterobacter spp., and evaluation of high-level temocillin resistance as a diagnostic marker for OXA-48 carbapenemase

(2013) N. Woodford et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Genomic analysis of the emergence and evolution of multidrug resistance during a Klebsiella pneumoniae outbreak including carbapenem and colistin resistance

(2013) E. Lopez-Camacho et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

An Increase in the Clinical Isolation of Acquired AmpC β-Lactamase-ProducingKlebsiella pneumoniaein Korea from 2007 to 2010

(2013) Min-Jeong Park et al.   Annals of Laboratory Medicine

Complete Deletion of theramRGene in anIn Vitro-Selected Mutant of Klebsiella pneumoniae Overexpressing the AcrAB Efflux Pump

(2012) Suzanne Bialek-Davenet et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Imipenem Resistance in Klebsiella pneumoniae Is Associated to the Combination of Plasmid-Mediated CMY-4 AmpC β-Lactamase and Loss of an Outer Membrane Protein

(2012) Safia Dahmen et al.   Microbial Drug Resistance

In Vitro Selection oframRandsoxRMutants Overexpressing Efflux Systems by Fluoroquinolones as Well as Cefoxitin in Klebsiella pneumoniae

(2011) Suzanne Bialek-Davenet et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In vitro activity of CXA-101 plus tazobactam (CXA-201) against CTX-M-14– and CTX-M-15–producing Escherichia coli and Klebsiella pneumoniae

(2011) Emilia Titelman et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

In vitro activity of avibactam (NXL104) in combination with β-lactams against Gram-negative bacteria, including OXA-48 β-lactamase-producing Klebsiella pneumoniae

(2011) Z. Aktaş et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Membrane Efflux and Influx Modulate both Multidrug Resistance and Virulence of Klebsiella pneumoniae in a Caenorhabditis elegans Model

(2010) S. Bialek et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In vivo selection of imipenem-resistant Klebsiella pneumoniae producing extended-spectrum β-lactamase CTX-M-15 and plasmid-encoded DHA-1 cephalosporinase

(2010) Gaelle Cuzon et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Multidrug-Resistant Gram-Negative Infections

(2009) Helen Giamarellou et al.   DRUGS

Development of ertapenem resistance in a patient with mediastinitis caused by Klebsiella pneumoniae producing an extended-spectrum  -lactamase

(2009) D. Skurnik et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Efflux Pump, the Masked Side of ß-Lactam Resistance in Klebsiella pneumoniae Clinical Isolates

(2009) Jean-Marie Pages et al.   PLoS One

Use of tigecycline for the treatment of prolonged bacteremia due to a multiresistant VIM-1 and SHV-12 β-lactamase–producing Klebsiella pneumoniae epidemic clone

(2007) Javier Cobo et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE