ZMYND10 functions in a chaperone relay during axonemal dynein assembly

Ciliary dynein motor preassembly is regulated by Wdr92 in association with HSP90 co-chaperone, R2TP

(2018) Petra zur Lage et al.   JOURNAL OF CELL BIOLOGY

RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex

(2018) Fabrizio Martino et al.   Nature Communications

ZMYND10 stabilizes intermediate chain proteins in the cytoplasmic pre-assembly of dynein arms

(2018) Kyeong Jee Cho et al.   PLoS Genetics

Systematic studies of all PIH proteins in zebrafish reveal their distinct roles in axonemal dynein assembly

(2018) Hiroshi Yamaguchi et al.   eLife

X-linked primary ciliary dyskinesia due to mutations in the cytoplasmic axonemal dynein assembly factor PIH1D3

(2017) Chiara Olcese et al.   Nature Communications

The structure of FKBP38 in complex with the MEEVD tetratricopeptide binding-motif of Hsp90

(2017) Katie L. I. M. Blundell et al.   PLoS One

DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes

(2016) Gerard W. Dougherty et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Transport of the outer dynein arm complex to cilia requires a cytoplasmic protein Lrrc6

(2016) Yasuko Inaba et al.   GENES TO CELLS

Fine-Tuning Motile Cilia and Flagella: Evolution of the Dynein Motor Proteins from Plants to Humans at High Resolution

(2016) Martin Kollmar   MOLECULAR BIOLOGY AND EVOLUTION

c21orf59/kurly Controls Both Cilia Motility and Polarization

(2016) Kimberly M. Jaffe et al.   Cell Reports

ZMYND10 - Mutation Analysis in Slavic Patients with Primary Ciliary Dyskinesia

(2016) Małgorzata Kurkowiak et al.   PLoS One

Substrate recognition and function of the R2TP complex in response to cellular stress

(2015) Patrick von Morgen et al.   Frontiers in Genetics

A Quantitative Chaperone Interaction Network Reveals the Architecture of Cellular Protein Homeostasis Pathways

(2014) Mikko Taipale et al.   CELL

Role of the ANKMY2-FKBP38 Axis in Regulation of the Sonic Hedgehog (Shh) Signaling Pathway

(2014) Shotaro Saita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pih1d3 is required for cytoplasmic preassembly of axonemal dynein in mouse sperm

(2014) Fenglan Dong et al.   JOURNAL OF CELL BIOLOGY

Structural Basis for Phosphorylation-Dependent Recruitment of Tel2 to Hsp90 by Pih1

(2014) Mohinder Pal et al.   STRUCTURE

HEATR2 Plays a Conserved Role in Assembly of the Ciliary Motile Apparatus

(2014) Christine P. Diggle et al.   PLoS Genetics

Mutations in ZMYND10, a Gene Essential for Proper Axonemal Assembly of Inner and Outer Dynein Arms in Humans and Flies, Cause Primary Ciliary Dyskinesia

(2013) Daniel J. Moore et al.   AMERICAN JOURNAL OF HUMAN GENETICS

ZMYND10 Is Mutated in Primary Ciliary Dyskinesia and Interacts with LRRC6

(2013) Maimoona A. Zariwala et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Feasibility for a large scale mouse mutagenesis by injecting CRISPR/Cas plasmid into zygotes

(2013) Daisuke Mashiko et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

DYX1C1 is required for axonemal dynein assembly and ciliary motility

(2013) Aarti Tarkar et al.   NATURE GENETICS

The CRAPome: a contaminant repository for affinity purification–mass spectrometry data

(2013) Dattatreya Mellacheruvu et al.   NATURE METHODS

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

High-Resolution Structural Analysis Shows How Tah1 Tethers Hsp90 to the R2TP Complex

(2013) Régis Back et al.   STRUCTURE

Acute Versus Chronic Loss of Mammalian Azi1/Cep131 Results in Distinct Ciliary Phenotypes

(2013) Emma A. Hall et al.   PLoS Genetics

Structure, Function and Regulation of the Hsp90 Machinery

(2013) Johannes Buchner et al.   Biomedical Journal

Loss-of-Function Mutations in LRRC6 , a Gene Essential for Proper Axonemal Assembly of Inner and Outer Dynein Arms, Cause Primary Ciliary Dyskinesia

(2012) Esther Kott et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A simple method to obtain pure cultures of multiciliated ependymal cells from adult rodents

(2012) J. M. Grondona et al.   HISTOCHEMISTRY AND CELL BIOLOGY

FK506 Binding Protein 8 Peptidylprolyl Isomerase Activity Manages a Late Stage of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Folding and Stability

(2012) Darren M. Hutt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutations in axonemal dynein assembly factor DNAAF3 cause primary ciliary dyskinesia

(2012) Hannah M Mitchison et al.   NATURE GENETICS

The R2TP complex: Discovery and functions

(2011) Yoshito Kakihara et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Ciliary motility: The components and cytoplasmic preassembly mechanisms of the axonemal dyneins

(2011) Daisuke Kobayashi et al.   DIFFERENTIATION

FKBP38 Peptidylprolyl Isomerase Promotes the Folding of Cystic Fibrosis Transmembrane Conductance Regulator in the Endoplasmic Reticulum

(2011) Yeshavanth K. Banasavadi-Siddegowda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia-inducible Factor Prolyl-4-hydroxylase PHD2 Protein Abundance Depends on Integral Membrane Anchoring of FKBP38

(2009) Sandra Barth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS

DNAI2 Mutations Cause Primary Ciliary Dyskinesia with Defects in the Outer Dynein Arm

(2008) Niki Tomas Loges et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Sentan: A Novel Specific Component of the Apical Structure of Vertebrate Motile Cilia

(2008) Akiharu Kubo et al.   MOLECULAR BIOLOGY OF THE CELL

Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins

(2008) Heymut Omran et al.   NATURE