Signals from the brain and olfactory epithelium control shaping of the mammalian nasal capsule cartilage

Multipotent peripheral glial cells generate neuroendocrine cells of the adrenal medulla

(2017) Alessandro Furlan et al.   SCIENCE

Decoding of position in the developing neural tube from antiparallel morphogen gradients

(2017) Marcin Zagorski et al.   SCIENCE

Oriented clonal cell dynamics enables accurate growth and shaping of vertebrate cartilage

(2017) Marketa Kaucka et al.   eLife

The Shh Topological Domain Facilitates the Action of Remote Enhancers by Reducing the Effects of Genomic Distances

(2016) Orsolya Symmons et al.   DEVELOPMENTAL CELL

Cis-regulatory architecture of a brain signaling center predates the origin of chordates

(2016) Yao Yao et al.   NATURE GENETICS

Craniofacial Ciliopathies Reveal Specific Requirements for GLI Proteins during Development of the Facial Midline

(2016) Ching-Fang Chang et al.   PLoS Genetics

Achondroplasia: Manifestations and Treatment

(2016) Eric D. Shirley et al.   JOURNAL OF THE AMERICAN ACADEMY OF ORTHOPAEDIC SURGEONS

Premigratory and Migratory Neural Crest Cells Are Multipotent In Vivo

(2015) Arianna Baggiolini et al.   Cell Stem Cell

A dynamic Shh expression pattern, regulated by SHH and BMP signaling, coordinates fusion of primordia in the amniote face

(2015) D. Hu et al.   DEVELOPMENT

Signals from the brain induce variation in avian facial shape

(2015) Diane Hu et al.   DEVELOPMENTAL DYNAMICS

Sonic hedgehog from pharyngeal arch 1 epithelium is necessary for early mandibular arch cell survival and later cartilage condensation differentiation

(2015) Katherine Kretovich Billmyre et al.   DEVELOPMENTAL DYNAMICS

A molecular mechanism for the origin of a key evolutionary innovation, the bird beak and palate, revealed by an integrative approach to major transitions in vertebrate history

(2015) Bhart-Anjan S. Bhullar et al.   EVOLUTION

Assessing the potential information content of multicomponent visual signals: a machine learning approach

(2015) W. L. Allen et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Cranial neural crest cell contribution to craniofacial formation, pathology, and future directions in tissue engineering

(2014) Taylor Nicholas Snider et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Whole-Brain Imaging with Single-Cell Resolution Using Chemical Cocktails and Computational Analysis

(2014) Etsuo A. Susaki et al.   CELL

Embryonic bauplans and the developmental origins of facial diversity and constraint

(2014) N. M. Young et al.   DEVELOPMENT

Homeostasis and Effector Function of Lymphopenia-Induced "Memory-Like" T Cells in Constitutively T Cell-Depleted Mice

(2014) D. Voehringer et al.   JOURNAL OF IMMUNOLOGY

Modeling first impressions from highly variable facial images

(2014) R. J. W. Vernon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vertebrate Limb Bud Formation Is Initiated by Localized Epithelial-to-Mesenchymal Transition

(2014) J. Gros et al.   SCIENCE

Holoprosencephaly: signaling interactions between the brain and the face, the environment and the genes, and the phenotypic variability in animal models and humans

(2014) Anna Petryk et al.   Wiley Interdisciplinary Reviews-Developmental Biology

Floor plate-derived sonic hedgehog regulates glial and ependymal cell fates in the developing spinal cord

(2013) K. Yu et al.   DEVELOPMENT

An Integrated Holo-Enhancer Unit Defines Tissue and Gene Specificity of the Fgf8 Regulatory Landscape

(2013) Mirna Marinić et al.   DEVELOPMENTAL CELL

Large deletions encompassing the TCOF1 and CAMK2A genes are responsible for Treacher Collins syndrome with intellectual disability

(2013) Marie Vincent et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Smart-seq2 for sensitive full-length transcriptome profiling in single cells

(2013) Simone Picelli et al.   NATURE METHODS

Fine Tuning of Craniofacial Morphology by Distant-Acting Enhancers

(2013) C. Attanasio et al.   SCIENCE

Gene Regulatory Logic for Reading the Sonic Hedgehog Signaling Gradient in the Vertebrate Neural Tube

(2012) Nikolaos Balaskas et al.   CELL

Evolutionary crossroads in developmental biology: cyclostomes (lamprey and hagfish)

(2012) S. M. Shimeld et al.   DEVELOPMENT

Fgf8 dosage determines midfacial integration and polarity within the nasal and optic capsules

(2012) John N. Griffin et al.   DEVELOPMENTAL BIOLOGY

Adaptive evolution of facial colour patterns in Neotropical primates

(2012) S. E. Santana et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Comparative genomics of the Hedgehog loci in chordates and the origins of Shh regulatory novelties

(2012) Manuel Irimia et al.   Scientific Reports

Phase I Trial of Hedgehog Pathway Inhibitor Vismodegib (GDC-0449) in Patients with Refractory, Locally Advanced or Metastatic Solid Tumors

(2011) P. M. LoRusso et al.   CLINICAL CANCER RESEARCH

Epigenetic integration of the developing brain and face

(2011) Trish E. Parsons et al.   DEVELOPMENTAL DYNAMICS

Signaling by SHH rescues facial defects following blockade in the brain

(2011) H. Jonathan Chong et al.   DEVELOPMENTAL DYNAMICS

Mechanisms that underlie co-variation of the brain and face

(2011) Ralph S. Marcucio et al.   GENESIS

RNAscope

(2011) Fay Wang et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells

(2010) Hugo J. Snippert et al.   CELL

Congenital craniofacial anomalies

(2010) Brian J Forbes   CURRENT OPINION IN OPHTHALMOLOGY

FGF10 controls the patterning of the tracheal cartilage rings via Shh

(2010) F. G. Sala et al.   DEVELOPMENT

Molecular mechanisms of cranial neural crest cell migration and patterning in craniofacial development

(2010) M. Minoux et al.   DEVELOPMENT

A cluster of three long-range enhancers directs regional Shh expression in the epithelial linings

(2009) T. Sagai et al.   DEVELOPMENT

Regulation of Sox9 by Sonic Hedgehog (Shh) is essential for patterning and formation of tracheal cartilage

(2009) Jinhyung Park et al.   DEVELOPMENTAL DYNAMICS

Comparative gene expression analysis of avian embryonic facial structures reveals new candidates for human craniofacial disorders

(2009) S.A. Brugmann et al.   HUMAN MOLECULAR GENETICS

Notochord-derived Shh concentrates in close association with the apically positioned basal body in neural target cells and forms a dynamic gradient during neural patterning

(2008) C. E. Chamberlain et al.   DEVELOPMENT

A SHH-responsive signaling center in the forebrain regulates craniofacial morphogenesis via the facial ectoderm

(2008) D. Hu et al.   DEVELOPMENT

Development and tissue origins of the mammalian cranial base

(2008) B. McBratney-Owen et al.   DEVELOPMENTAL BIOLOGY

The neurocognitive phenotype in velo-cardio-facial syndrome: A developmental perspective

(2008) Kevin M. Antshel et al.   Developmental Disabilities Research Reviews