A novel source of arterial valve cells linked to bicuspid aortic valve without raphe in mice

Development and maturation of the fibrous components of the arterial roots in the mouse heart

(2017) Rachel Richardson et al.   JOURNAL OF ANATOMY

Sequential Ligand-Dependent Notch Signaling Activation Regulates Valve Primordium Formation and MorphogenesisNovelty and Significance

(2016) Donal MacGrogan et al.   CIRCULATION RESEARCH

Morphogenesis of myocardial trabeculae in the mouse embryo

(2016) Gabriella Captur et al.   JOURNAL OF ANATOMY

Disrupted Slit-Robo signalling results in membranous ventricular septum defects and bicuspid aortic valves

(2015) Mathilda T.M. Mommersteeg et al.   CARDIOVASCULAR RESEARCH

Enabling research with human embryonic and fetal tissue resources

(2015) D. Gerrelli et al.   DEVELOPMENT

Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease

(2015) Brynn N. Akerberg et al.   DEVELOPMENTAL BIOLOGY

Sequential Notch activation regulates ventricular chamber development

(2015) Gaetano D’Amato et al.   NATURE CELL BIOLOGY

TBX1 regulates epithelial polarity and dynamic basal filopodia in the second heart field

(2014) A. Francou et al.   DEVELOPMENT

Heart Fields and Cardiac Morphogenesis

(2014) R. G. Kelly et al.   Cold Spring Harbor Perspectives in Medicine

Vangl2-Regulated Polarisation of Second Heart Field-Derived Cells Is Required for Outflow Tract Lengthening during Cardiac Development

(2014) Simon A. Ramsbottom et al.   PLoS Genetics

Neural crest cells are required for correct positioning of the developing outflow cushions and pattern the arterial valve leaflets

(2013) Helen M. Phillips et al.   CARDIOVASCULAR RESEARCH

Second heart field and the development of the outflow tract in human embryonic heart

(2013) Yan-Ping Yang et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Nkx2-5 lineage tracing visualizes the distribution of second heart field-derived aortic smooth muscle

(2013) Andrew W. Harmon et al.   GENESIS

Non-parallel recombination limits cre-loxP-based reporters as precise indicators of conditional genetic manipulation

(2013) Jing Liu et al.   GENESIS

Endocardial to Myocardial Notch-Wnt-Bmp Axis Regulates Early Heart Valve Development

(2013) Yidong Wang et al.   PLoS One

Normal and abnormal development of the intrapericardial arterial trunks in humans and mice

(2012) Robert H. Anderson et al.   CARDIOVASCULAR RESEARCH

Epicardially derived fibroblasts preferentially contribute to the parietal leaflets of the atrioventricular valves in the murine heart

(2012) Andy Wessels et al.   DEVELOPMENTAL BIOLOGY

Morphogenesis of outflow tract rotation during cardiac development: The pulmonary push concept

(2012) Roderick W.C. Scherptong et al.   DEVELOPMENTAL DYNAMICS

Atrioventricular valve development: New perspectives on an old theme

(2012) Annemarieke de Vlaming et al.   DIFFERENTIATION

Three-dimensional and molecular analysis of the arterial pole of the developing human heart

(2012) Aleksander Sizarov et al.   JOURNAL OF ANATOMY

Deficient Signaling via Alk2 (Acvr1) Leads to Bicuspid Aortic Valve Development

(2012) Penny S. Thomas et al.   PLoS One

Endogenous Cardiac Troponin T Modulates Ca2+-Mediated Smooth Muscle Contraction

(2012) Shunichi Kajioka et al.   Scientific Reports

Heart Valve Structure and Function in Development and Disease

(2011) Robert B. Hinton et al.   Annual Review of Physiology

Variable phenotypes of bicuspid aortic valve disease: classification by cardiovascular magnetic resonance

(2010) S. Buchner et al.   HEART

Integration of a Notch-dependent mesenchymal gene program and Bmp2-driven cell invasiveness regulates murine cardiac valve formation

(2010) Luis Luna-Zurita et al.   JOURNAL OF CLINICAL INVESTIGATION

Cardiac neural crest orchestrates remodeling and functional maturation of mouse semilunar valves

(2010) Rajan Jain et al.   JOURNAL OF CLINICAL INVESTIGATION

Partial rescue of the Tbx1 mutant heart phenotype by Fgf8: Genetic evidence of impaired tissue response to Fgf8

(2010) Francesca Vitelli et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Bicuspid Aortic Valve Disease

(2010) Samuel C. Siu et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Outflow tract cushions perform a critical valve-like function in the early embryonic heart requiring BMPRIA-mediated signaling in cardiac neural crest

(2009) Aya Nomura-Kitabayashi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Ascending Aortic Dilatation Associated With Bicuspid Aortic Valve

(2009) Thomas M. Tadros et al.   CIRCULATION

A regulatory pathway involving Notch1/β-catenin/Isl1 determines cardiac progenitor cell fate.

(2009) Chulan Kwon et al.   NATURE CELL BIOLOGY

Notch pathway regulation of chondrocyte differentiation and proliferation during appendicular and axial skeleton development

(2009) T. J. Mead et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The del22q11.2 Candidate Gene Tbx1 Controls Regional Outflow Tract Identity and Coronary Artery Patterning

(2008) Magali Théveniau-Ruissy et al.   CIRCULATION RESEARCH

Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart

(2008) Bin Zhou et al.   NATURE

Myocardium at the base of the aorta and pulmonary trunk is prefigured in the outflow tract of the heart and in subdomains of the second heart field

(2007) Fanny Bajolle et al.   DEVELOPMENTAL BIOLOGY