Setup and Validation of an MPI Signal Chain for a Drive Field Frequency of 150 kHz

In this paper, an imaging system is considered, which is part of an activity to test the feasibility of clinical (whole-body) magnetic particle imaging (MPI). Recent studies on nerve stimulation in humans indicate that drive field amplitudes have to be limited to lower values compared with preclinical MPI. Since nerve stimulation thresholds increase with frequency, the drive field frequency for the clinical demonstrator is set to 150 kHz. To date, available MPI systems usually apply drive fields at frequencies ranging from 1 to 25 kHz. We report on the technical feasibility of a signal chain setup for a drive field frequency of 150 kHz.