Review
Medicine, General & Internal
Zhenpeng Yang, Huazhen Tang, Shuai Lu, Xibo Sun, Benqiang Rao
Summary: This meta-analysis aims to clarify the relationship between serum lipid levels and the risk of colorectal cancer (CRC) by analyzing published prospective studies. The results indicate that high triglyceride (TG) and total cholesterol (TC) levels are positively associated with the incidence rate of CRC, while high-density lipoprotein cholesterol (HDL-C) levels are negatively associated with CRC incidence rate. However, no significant association was observed between low-density lipoprotein cholesterol (LDL-C) and the risk of developing CRC.
Review
Medicine, General & Internal
Shutang Zhao, Xiren Wang
Summary: This study systematically reviewed the relationship between enteral nutrition and serum inflammatory factors and cardiac function in elderly patients with heart failure (HF), aiming to provide new medical evidence for clinical treatment. The findings are expected to offer compelling evidence and improved guidance in clinic settings for the application of enteral nutrition in elderly patients with HF.
Article
Medicine, General & Internal
Xinyi Li, Xiaonan Zhang, Yaoxin Liu, Fen Shu, Sisi Shao, Ning Tan, Lei Jiang
Summary: Serum chloride concentration is a prognostic indicator in elderly patients with NIDCM, and hypochloremia is significantly associated with both in-hospital and long-term poor outcomes.
Review
Medicine, Research & Experimental
Hecheng Wang, Pengpeng Wu, Deying Jiang, Hao Zhang, Jian Zhang, Yu Zong, Yanshuo Han
Summary: This meta-analysis provides evidence that elevated levels of serum homocysteine, fibrinogen, and lipoprotein-a may increase the risk of peripheral arterial disease, and the risk increases within a certain range of serum exposure.
EUROPEAN JOURNAL OF MEDICAL RESEARCH
(2022)
Article
Medicine, General & Internal
Yves Cottin, Brahim Maalem Ben Messaoud, Antoine Monin, Pierre Guilleminot, Arnaud Bisson, Jean-Christophe Eicher, Alexandre Bodin, Julien Herbert, Yves Juilliere, Marianne Zeller, Laurent Fauchier
Summary: Patients with HF preceding AF (prevalent HF) had higher mortality and higher risk of re-hospitalization for HF, while those with AF preceding HF (incident HF) had a higher risk of ischemic stroke.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Vlad-Sabin Ivan, Roxana Buzas, Adina-Flavia Cutina Morgovan, Paul Ciubotaru, Melania Ardelean, Daniel Goje, Ilie Rosca Ciprian, Romulus Timar, Daniel Lighezan
Summary: The study examined the direct relationship between serum uric acid and ejection fraction in 303 heart failure patients, concluding that higher uric acid levels are associated with a lower ejection fraction of the left ventricle.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Ling Xie, Zhen Zhou, Hai-Xiao Chen, Xiao-Yun Yan, Jia-Qi Ye, Ying Jiang, Lei Zhou, Qing Zhang
Summary: This study aimed to investigate the correlation between serum laminin (LN) levels and clinical stages of heart failure in patients with chronic heart failure. The results showed that serum LN levels in patients with chronic heart failure were significantly increased and independently correlated with the clinical stages of heart failure. Therefore, serum LN levels could potentially serve as an early warning index of the progression and severity of heart failure.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Jawad H. Butt, Toru Kondo, Mingming Yang, Pardeep S. Jhund, Kieran F. Docherty, Muthiah Vaduganathan, Brian L. Claggett, Adrian F. Hernandez, Carolyn S. P. Lam, Silvio E. Inzucchi, Felipe A. Martinez, Rudolf A. de Boer, Mikhail N. Kosiborod, Akshay S. Desai, Lars Kober, Piotr Ponikowski, Marc S. Sabatine, Sanjiv J. Shah, Natalia Zaozerska, Ulrica Wilderang, Olof Bengtsson, Scott D. Solomon, John J. McMurray
Summary: This study aimed to assess the efficacy and safety of dapagliflozin in patients with heart failure, particularly in those with peripheral artery disease (PAD). The results showed that dapagliflozin was equally effective in patients with and without PAD and did not increase the risk of amputation.
EUROPEAN HEART JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Katsuhiko Ohori, Toshiyuki Yano, Satoshi Katano, Ryohei Nagaoka, Ryo Numazawa, Kotaro Yamano, Yusuke Fujisawa, Hidemichi Kouzu, Nobutaka Nagano, Takefumi Fujito, Ryo Nishikawa, Wataru Ohwada, Tatsuya Sato, Masato Furuhashi
Summary: Iron deficiency affects physical function in heart failure patients and shows different associations in patients with and without diabetes.
Review
Public, Environmental & Occupational Health
Senjun Jin, Chaozhou Hu, Yanmei Zheng
Summary: This study conducted a meta-analysis and found that maternal zinc levels were lower in women with preeclampsia compared to healthy pregnant women. The severity of the disease, geographical and economic context may further influence serum zinc levels and preeclampsia.
FRONTIERS IN PUBLIC HEALTH
(2022)
Review
Dentistry, Oral Surgery & Medicine
Sadeq A. i Al-Maweri, Esam Halboub, Hesham Mohammed Al-Sharani, Anas Shamala, Ahlam Al-Kamel, Mohammed Al-Wesabi, Abdullkhaleg Albashari, Amani Al-Sharani, Saleem Abdulrab
Summary: The meta-analysis found a significant association between low serum zinc levels and the occurrence of RAS. Subgroup analysis by geographic distribution showed that the association was significant in both Chinese and other populations, with a more pronounced effect in the Chinese subgroup. Trial sequential analysis confirmed the reliability of the results, while also encouraging further large-scale studies of high quality.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Cardiac & Cardiovascular Systems
Hongxuan Xu, Quan Wang, Yunqing Liu, Lingbing Meng, Huanyu Long, Li Wang, Deping Liu
Summary: The study found that both high and low uric acid levels are predictive of hypertensive heart failure, while high-density lipoprotein cholesterol and fasting blood sugar are also associated with this condition, but low-density lipoprotein cholesterol is not correlated.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Review
Biochemistry & Molecular Biology
Endalamaw Tesfa, Endalkachew Nibret, Abaineh Munshea
Summary: The study found that the maternal serum zinc levels were significantly lower in pre-eclamptic women compared to normotensive pregnant women, suggesting a potential association between zinc and the development of pre-eclampsia. However, the specific role of zinc in the pathogenesis of pre-eclampsia needs to be confirmed in large-scale clinical trials.
BIOLOGICAL TRACE ELEMENT RESEARCH
(2021)
Article
Cardiac & Cardiovascular Systems
Zhendong Cheng, Kefeng Cai, Chaoxian Xu, Qiong Zhan, Xingbo Xu, Dingli Xu, Qingchun Zeng
Summary: This study evaluated the association between serum galectin-3 and all-cause death (ACD) and cardiovascular death (CVD) in patients with chronic heart failure (CHF). The results showed that higher serum galectin-3 levels were associated with an increased risk of ACD and CVD in CHF patients. Subgroup analysis revealed that the risk was higher in the shorter follow-up group. These findings suggest that serum galectin-3 may have prognostic value and could be useful for risk classification in CHF patients.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Niels T. B. Scholte, Muhammed T. Gurgoze, Dilan Aydin, Dominic A. M. J. Theuns, Olivier C. Manintveld, Eelko Ronner, Eric Boersma, Rudolf A. de Boer, Robert M. A. van der Boon, Jasper J. Brugts
Summary: A comprehensive meta-analysis suggests that home telemonitoring systems (hTMS) can significantly reduce all-cause mortality and heart failure-related hospitalizations in heart failure patients.
EUROPEAN HEART JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Qingmei Cui, Zhongying Liu, Jianxin Li, Fangchao Liu, Xiaoge Niu, Chong Shen, Dongsheng Hu, Keyong Huang, Shufeng Chen, Yingxin Zhao, Fanghong Lu, Xiaoqing Liu, Jie Cao, Laiyuan Wang, Hongxia Ma, Ling Yu, Xianping Wu, Ying Li, Huan Zhang, Xingbo Mo, Liancheng Zhao, Zhibin Hu, Hongbing Shen, Jianfeng Huang, Xiangfeng Lu, Dongfeng Gu
Summary: This study aims to examine whether adherence to ideal cardiovascular health (CVH) can mitigate the genetic risk of coronary artery disease (CAD) in non-European populations. The results showed that individuals with a favourable CVH profile demonstrated similar relative effects across Polygenic Risk Score (PRS) categories, reducing the CAD relative risk by a similar magnitude. Individuals with high PRS achieved the greatest benefit from favourable CVH, mitigating the risk to the average level of the population. Attaining favourable CVH should be encouraged for all individuals, especially those with high genetic susceptibility.
Article
Peripheral Vascular Disease
Xuanming Hong, Ke Miao, Weihua Cao, Jun Lv, Canqing Yu, Tao Huang, Dianjianyi Sun, Chunxiao Liao, Yuanjie Pang, Zengchang Pang, Min Yu, Hua Wang, Xianping Wu, Yu Liu, Wenjing Gao, Liming Li
Summary: This study identified CpG sites associated with systolic and diastolic blood pressure and examined the temporal relationship between DNA methylation and blood pressure. The findings suggest the significance of DNA methylation in the development of hypertension.
Article
Peripheral Vascular Disease
Han Ma, Fangchao Liu, Jianxin Li, Jichun Chen, Jie Cao, Shufeng Chen, Xiaoqing Liu, Xueli Yang, Keyong Huang, Chong Shen, Ling Yu, Yingxin Zhao, Xianping Wu, Liancheng Zhao, Ying Li, Dongsheng Hu, Jianfeng Huang, Xiangfeng Lu, Dongfeng Gu
Summary: Based on a study conducted in China, the association between socioeconomic status (SES) and hypertension remains uncertain. Individuals with lower SES are at a higher risk of developing hypertension compared to those with higher SES. Moreover, women are more susceptible to the adverse effects of lower SES on hypertension.
Article
Automation & Control Systems
Ying Li, Aimin Zhang, Jingjing Huang, Zhe Xu
Summary: This paper proposes a prediction method based on a back adoptive adjustment transfer learning scheme for the degradation prediction of dry-type transformers. By constructing a deep neural network, a transfer learning module, and a back adjustment module, it can extract features, adapt to different domains, and optimize the prediction network, thereby improving prediction accuracy and addressing the problems and drawbacks of traditional methods. The proposed method also exhibits strong portability and application potential.
IEEE TRANSACTIONS ON INDUSTRIAL ELECTRONICS
(2023)
Review
Biochemistry & Molecular Biology
Ting Zhang, Qi Liu, Zhuo Li, Siqi Tang, Qimin An, Dongdong Fan, Yiwei Xiang, Xianli Wu, Zhe Jin, Jianhong Ding, Yanxia Hu, Qian Du, Jingyu Xu, Rui Xie
Summary: Ion channels are integral membrane proteins that allow the permeation of charge ions across hydrophobic phospholipid membranes. They play a crucial role in establishing membrane potential by regulating ion concentration, and are involved in various immune-related diseases in major human organs.
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Shanliang Dong, Kemiao Hong, Zhijing Zhang, Jingjing Huang, Xiongda Xie, Haoxuan Yuan, Wenhao Hu, Xinfang Xu
Summary: The construction of all-carbon quaternary stereocenters has attracted significant attention in catalytic asymmetric reactions. This study presents a rare and challenging asymmetric multi-component reaction that builds two C-C bonds on the same carbonic center to form quaternary stereocenters. The reaction is achieved through dirhodium/chiral phosphoric acid cooperative catalysis and provides a practical and atom-economic synthesis of poly-functionalized chiral ketones in good to high yields and excellent enantioselectivities. It offers an unprecedented gem-dialkylation process, which complements previous methods for constructing tertiary and quaternary stereocenters and utilizes readily available starting materials.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Energy & Fuels
Xianguo Wu, Xinyi Li, Yawei Qin, Wen Xu, Yang Liu
Summary: In this study, an intelligent optimization method integrating the BIM-DB and PSO-RF-NSGA-III methods was established for the energy saving design and optimization of near-zero-energy-consumption buildings (NZEBs). The method was applied to explore multiobjective optimization problems in four typical climate regions in China. The results showed that the PSO-RF algorithm efficiently predicted building energy consumption, carbon emissions, and thermal comfort. After optimization, the energy consumption levels in the four regions were reduced by 39.72%, 32.22%, 26.94%, and 35.37%, respectively, and other goals were also optimized. The optimized building design parameters met the standards for NZEBs, with varying influencing factors and measures across different regions.
Article
Mathematics, Applied
Xian Wu, Kaihua Xi, Aijie Cheng, Hai Xiang Lin, Jan H. H. van Schuppen
Summary: We aim to enhance the ability of coupled phase oscillators to maintain synchronization under stochastic disturbances by proposing an optimization method. We model the disturbances as Gaussian noise and measure synchronization stability using mean first hitting time. The optimization method increases the mean first hitting time and identifies vulnerable edges in the system, increasing synchronization stability.
Correction
Physics, Multidisciplinary
Yuhao Gu, Kun Jiang, Xianxin Wu, Jiangping Hu
CHINESE PHYSICS LETTERS
(2023)
Article
Multidisciplinary Sciences
Cun Li, Jingjing Huang, Yifei Yu, Zhixin Wan, Man Chun Chiu, Xiaojuan Liu, Shuxin Zhang, Jian-Piao Cai, Hin Chu, Gang Li, Jasper Fuk-Woo Chan, Kelvin Kai-Wang To, Zifeng Yang, Shibo Jiang, Kwok-yung Yuen, Hans Clevers, Jie Zhou
Summary: The high transmissibility of SARS-CoV-2 Omicron subvariants is attributed to immune escape. BA.5 showed significantly increased replicative capacity and infectivity in human respiratory epithelial cells. BA.5 has a higher entry efficiency and fusogenic activity, promoting viral spread through syncytium formation in the airway epithelium, while its replicative capacity in alveolar cells is attenuated, which may explain its milder clinical manifestation.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2023)
Article
Environmental Sciences
Yiyun Liu, Jingjing Huang, Wei Wang, Guanghong Sheng, Shisheng Wang, Jun Wu, Jianjun Li
Summary: This paper proposes a decision-making approach based on the triple bottom line concept to evaluate the sustainability of demand-oriented biogas supply programs. An indicator system is developed, with parameters quantified through emergy analysis, economic benefit assessment, and a social risk accounting method. The Charnes-Cooper-Wei-Huang model is used to calculate comprehensive sustainability, considering economic, environmental, and social indicators. The evaluation results show that the scenario of supplying real-time varying power demand using straw and livestock manure has the highest sustainability score in this case study. Managerial implications are proposed based on the results.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Psychiatry
Zelin Yuan, Huamin Liu, Xiaochun Zhang, Yong He, Shanyuan Gu, Dan Mo, Shaoli Wang, Zhiwei Huang, Keyi Wu, Rui Zhou, Qi Zhong, Yining Huang, Bifei Cao, Haowen Chen, Xianbo Wu
Summary: Previous studies have found that high uric acid (UA) is associated with enhanced patient function. This study aims to clarify the relationship between UA and cognitive impairment in patients with schizophrenia (SCZ) and explore whether UA could be used as a potential biological marker of cognition in SCZ during maintenance period. The results showed that UA is positively associated with cognitive function, and high UA is associated with enhanced cognition in patients with low anticholinergic cognitive burden (ACB).
FRONTIERS IN PSYCHIATRY
(2023)
Article
Multidisciplinary Sciences
Kun Liao, Yangguang Zhong, Zhuochen Du, Guodong Liu, Chentong Li, Xianxin Wu, Chunhua Deng, Cuicui Lu, Xingyuan Wang, Che Ting Chan, Qinghai Song, Shufeng Wang, Xinfeng Liu, Xiaoyong Hu, Qihuang Gong
Summary: In this paper, a scalable strategy is proposed to realize a robust on-chip integrated visible microlaser with improved lasing performance. The strategy is experimentally verified by demonstrating a second-order exceptional surface-tailored microlaser and further discussed for potential applications. This work lays a foundation for the development of high-speed visible-light communication and processing systems, provides a platform for the study of non-Hermitian photonics, and proposes a feasible method of joint research for non-Hermitian photonics with nonlinear optics and topological photonics.
Article
Engineering, Electrical & Electronic
Jun Pan, Xiaoou Liu, Jingjing Huang
Summary: The key idea of this paper is that under the goal of carbon emissions peak and carbon neutrality, virtual power plants (VPPs) are significant in improving grid safety and promoting clean, low-carbon energy transition. However, the intermittent output of renewable energy and the heat-based operation of combined heat and power (CHP) units in winter heating areas contradict each other and affect the peak-load regulating capacity of VPPs, leading to high carbon emissions. To solve this problem, the paper proposes a multi-level games optimal scheduling strategy of multiple VPPs considering carbon emission flow and carbon trade.
ELECTRIC POWER SYSTEMS RESEARCH
(2023)
Article
Thermodynamics
Junyu Liu, Zhiwu Wang, Weifeng Qin, Junlin Li, Zixu Zhang, Jingjing Huang
Summary: The pulse detonation turbine engine (PDTE) has the potential performance advantage, but the unsteadiness and flow losses during detonation severely limit engine performance. Adjusting the detonation initial conditions could greatly improve the performance of the PDTE. This paper numerically investigates the performance of the PDTE with different hydrogen-air mixture equivalence ratios and initial temperatures, and analyzes the turbine efficiency and PDC combustion efficiency to provide guidance for thermal efficiency analysis.
